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To understand how genetic variants in human genomes manifest in phenotypes -- traits like height or diseases like asthma -- geneticists have sequenced and measured hundreds of thousands of individuals. Geneticists use this data to build…

Machine Learning · Computer Science 2025-07-01 Alan N. Amin , Andres Potapczynski , Andrew Gordon Wilson

Variant calling, the problem of estimating whether a position in a DNA sequence differs from a reference sequence, given noisy, redundant, overlapping short sequences that cover that position, is fundamental to genomics. We propose a deep…

Genomics · Quantitative Biology 2020-03-17 Nikolai Yakovenko , Avantika Lal , Johnny Israeli , Bryan Catanzaro

Prediction of mRNA gene-expression profiles directly from routine whole-slide images (WSIs) using deep learning models could potentially offer cost-effective and widely accessible molecular phenotyping. While such WSI-based gene-expression…

Genomics · Quantitative Biology 2024-10-03 Fredrik K. Gustafsson , Mattias Rantalainen

DNA sequencing to identify genetic variants is becoming increasingly valuable in clinical settings. Assessment of variants in such sequencing data is commonly implemented through Bayesian heuristic algorithms. Machine learning has shown…

The data scarcity problem in emotion recognition from electroencephalography (EEG) leads to difficulty in building an affective model with high accuracy using machine learning algorithms or deep neural networks. Inspired by emerging deep…

Signal Processing · Electrical Eng. & Systems 2020-06-18 Yun Luo , Li-Zhen Zhu , Zi-Yu Wan , Bao-Liang Lu

Generative recommendation plays a crucial role in personalized systems, predicting users' future interactions from their historical behavior sequences. A critical yet underexplored factor in training these models is data augmentation, the…

Machine Learning · Computer Science 2026-05-21 Geon Lee , Bhuvesh Kumar , Clark Mingxuan Ju , Tong Zhao , Kijung Shin , Neil Shah , Liam Collins

Sequence-to-Sequence (S2S) models recently started to show state-of-the-art performance for automatic speech recognition (ASR). With these large and deep models overfitting remains the largest problem, outweighing performance improvements…

Audio and Speech Processing · Electrical Eng. & Systems 2020-02-04 Thai-Son Nguyen , Sebastian Stueker , Jan Niehues , Alex Waibel

Weak supervision combines the advantages of training on real data with the ability to exploit signal properties. However, training a neural network using weak supervision often requires an excessive amount of signal data, which severely…

High Energy Physics - Phenomenology · Physics 2024-12-23 Zong-En Chen , Cheng-Wei Chiang , Feng-Yang Hsieh

Data augmentation is usually adopted to increase the amount of training data, prevent overfitting and improve the performance of deep models. However, in practice, random data augmentation, such as random image cropping, is low-efficiency…

Computer Vision and Pattern Recognition · Computer Science 2019-03-26 Tao Hu , Honggang Qi , Qingming Huang , Yan Lu

Generative models excel in creating realistic images, yet their dependency on extensive datasets for training presents significant challenges, especially in domains where data collection is costly or challenging. Current data-efficient…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Yuta Mimura

Data augmentation is a ubiquitous technique for increasing the size of labeled training sets by leveraging task-specific data transformations that preserve class labels. While it is often easy for domain experts to specify individual…

Machine Learning · Statistics 2018-12-10 Alexander J. Ratner , Henry R. Ehrenberg , Zeshan Hussain , Jared Dunnmon , Christopher Ré

Genome-wide association studies (GWAS) have identified hundreds of loci at very stringent levels of statistical significance across many different human traits. However, it is now clear that very large samples (n~10^4-10^5) are needed to…

Genomics · Quantitative Biology 2013-08-20 Inti Pedroso

Data augmentation is a powerful tool for improving deep learning-based image classifiers for plant stress identification and classification. However, selecting an effective set of augmentations from a large pool of candidates remains a key…

Computer Vision and Pattern Recognition · Computer Science 2024-06-21 Nasla Saleem , Aditya Balu , Talukder Zaki Jubery , Arti Singh , Asheesh K. Singh , Soumik Sarkar , Baskar Ganapathysubramanian

Data augmentations are useful in closing the sim-to-real domain gap when training on synthetic data. This is because they widen the training data distribution, thus encouraging the model to generalize better to other domains. Many image…

Computer Vision and Pattern Recognition · Computer Science 2024-03-12 Bram Vanherle , Nick Michiels , Frank Van Reeth

Deep artificial neural networks require a large corpus of training data in order to effectively learn, where collection of such training data is often expensive and laborious. Data augmentation overcomes this issue by artificially inflating…

Machine Learning · Computer Science 2017-08-22 Luke Taylor , Geoff Nitschke

Whole and targeted sequencing of human genomes is a promising, increasingly feasible tool for discovering genetic contributions to risk of complex diseases. A key step is calling an individual's genotype from the multiple aligned short read…

Applications · Statistics 2012-06-29 Baiyu Zhou , Alice S. Whittemore

Metagenomics characterizes the taxonomic diversity of microbial communities by sequencing DNA directly from an environmental sample. One of the main challenges in metagenomics data analysis is the binning step, where each sequenced read is…

Quantitative Methods · Quantitative Biology 2015-05-27 Kévin Vervier , Pierre Mahé , Maud Tournoud , Jean-Baptiste Veyrieras , Jean-Philippe Vert

Data augmentation is a technique to generate new training data based on existing data. We evaluate the simple and cost-effective method of concatenating the original data examples to build new training instances. Continued training with…

Computation and Language · Computer Science 2023-06-12 Tsz Kin Lam , Shigehiko Schamoni , Stefan Riezler

Genomic selection (GS), as a critical crop breeding strategy, plays a key role in enhancing food production and addressing the global hunger crisis. The predominant approaches in GS currently revolve around employing statistical methods for…

Machine Learning · Computer Science 2024-06-25 Renqi Chen , Wenwei Han , Haohao Zhang , Haoyang Su , Zhefan Wang , Xiaolei Liu , Hao Jiang , Wanli Ouyang , Nanqing Dong

The training of molecular models of quantum mechanical properties based on statistical machine learning requires large datasets which exemplify the map from chemical structure to molecular property. Intelligent a priori selection of…

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