English
Related papers

Related papers: Heterogeneities Shape Passive Intracellular Transp…

200 papers

In this work, we investigate the large-scale transport properties of a passive scalar advected by a turbulent fluid, modelled as a superposition of divergence-free vector fields, each weighted by an independent symmetric…

Mathematical Physics · Physics 2026-02-25 Paolo Cifani , Franco Flandoli , Lorenzo Marino

The motility of adherent eukaryotic cells is driven by the dynamics of the actin cytoskeleton. Despite the common force-generating actin machinery, different cell types often show diverse modes of locomotion that differ in their shape…

Biological Physics · Physics 2022-07-15 T. Moldenhawer , E. Moreno , D. Schindler , S. Flemming , M. Holschneider , W. Huisinga , S. Alonso , C. Beta

Cytoplasmic dyneins transport cellular organelles by moving on a microtubule filament. It has been found recently that depending on the applied force and the concentration of the adenosine triphosphate (ATP) molecules, dynein's step size…

Statistical Mechanics · Physics 2009-11-13 Sutapa Mukherji

Transport of dense core vesicles (DCVs) in neurons is crucial for distributing molecules like neuropeptides and growth factors. We studied the experimental trajectories of dynein-driven directed movement of DCVs in the ALA neuron C. elegans…

Subcellular Processes · Quantitative Biology 2025-03-04 Anna Gavrilova , Nickolay Korabel , Victoria J. Allan , Sergei Fedotov

Spatial distributions of morphogens provide positional information in developing systems, but how the distributions are established and maintained remains an open problem. Transport by diffusion has been the traditional mechanism, but…

Cell Behavior · Quantitative Biology 2022-11-23 Jay A. Stotsky , Hans G. Othmer

The integration of motile cells into biohybrid microrobots offers unique properties such as sensitive responses to external stimuli, resilience, and intrinsic energy supply. Here we study biohybrid microtransporters that are driven by…

Biological Physics · Physics 2023-11-08 Setareh Sharifi Panah , Robert Großmann , Valentino Lepro , Carsten Beta

The process of diffusion is the most elementary stochastic transport process. Brownian motion, the representative model of diffusion, played a important role in the advancement of scientific fields such as physics, chemistry, biology and…

Statistical Mechanics · Physics 2015-08-11 Alexandre Bovet

Last year in [Phys. Rev. E 102, 042121 (2020)] the authors studied an overdamped dynamics of nonequilibrium noise driven Brownian particle dwelling in a spatially periodic potential and discovered a novel class of Brownian, yet non-Gaussian…

Statistical Mechanics · Physics 2021-12-22 Karol Białas , Jakub Spiechowicz

Several theoretical models based on totally asymmetric simple exclusion process (TASEP) have been extensively utilized to study various non-equilibrium transport phenomena. Inspired by the the role of microtubule-transported vesicles in…

Statistical Mechanics · Physics 2021-02-03 Akriti Jindal , Atul Kumar Verma , Arvind Kumar Gupta

On long enough timescales, chaotic diffusion has the potential to significantly alter the appearance of a dynamical system. The solar system is no exception: diffusive processes take part in the transportation of small bodies and provide…

Earth and Planetary Astrophysics · Physics 2023-06-14 Emese Kővári , Emese Forgács-Dajka , Tamás Kovács , Csaba Kiss , Zsolt Sándor

Transport of nanoscale objects in complex, structured environments plays a key role in a wide range of processes, from biomolecular dynamics in extracellular spaces to transport in porous materials such as filters and catalysts. While…

The spontaneous generation of electrical activity underpins a number of essential physiological processes, and is observed even in tissues where specialized pacemaker cells have not been identified. The emergence of periodic oscillations in…

Adaptation and Self-Organizing Systems · Physics 2022-02-01 Ria Ghosh , Shakti N. Menon

We show how the nonlinear interaction effects `volume filling' and `adhesion' can be incorporated into the fractional subdiffusive transport of cells and individual organisms. To this end, we use microscopic random walk models with…

Statistical Mechanics · Physics 2015-01-20 Peter Straka , Sergei Fedotov

Cyclic loading is a common feature in poroelastic systems, the material response depending non-trivially on the exact form of boundary conditions, pore structure, and mechanical properties. The situation becomes more complex when…

Soft Condensed Matter · Physics 2025-10-08 Zoe C. Godard , Derek E. Moulton , Sarah L. Waters

The stochastic motion in a nonhomogeneous medium with traps is studied and diffusion properties of that system are discussed. The particle is subjected to a stochastic stimulation obeying a general L\'evy stable statistics and experiences…

Statistical Mechanics · Physics 2015-06-11 Tomasz Srokowski

Observations of single epidermal cells on flat adhesive substrates have revealed two distinct morphological and functional states, namely a non-migrating symmetric unpolarized state and a migrating asymmetric polarized state. These states…

Biological Physics · Physics 2010-04-14 Wolfgang Alt , Martin Bock , Christoph Möhl

In cell membranes, proteins and lipids diffuse in a highly crowded and heterogeneous landscape, where aggregates and dense domains of proteins or lipids obstruct the path of diffusing molecules. In general, hindered motion gives rise to…

Soft Condensed Matter · Physics 2010-06-16 Margaret R. Horton , Felix Höfling , Joachim O. Rädler , Thomas Franosch

We consider the diffusion-advection problem in two simple cellular flow models (often invoked as examples for subdiffusive tracer's motion) and concentrate on the intermediate time range, in which the tracer's motion indeed may show…

Fluid Dynamics · Physics 2016-09-28 Patrick Pöschke , Igor M. Sokolov , Alexander A. Nepomnyashchy , Michael A. Zaks

We analyze the nonlinear waves that propagate on a microtubule that is tethered at its minus end due to kinesin walking on it, as is seen during the fluid mixing caused by cytoplasmic streaming in Drosophila oocytes.The model we use assumes…

Biomolecules · Quantitative Biology 2012-07-11 J. M. Deutsch , M. E. Brunner , William M. Saxton

Cell migration is a fundamental process for life and is highly dependent on the dynamical and mechanical properties of the cytoskeleton. Intensive physical and biochemical crosstalk between actin, microtubules, and intermediate filaments…

Biological Physics · Physics 2024-01-17 James P. Conboy , Irene Istúriz Petitjean , Anouk van der Net , Gijsje H. Koenderink