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Objective: In this paper, we develop a personalized real-time risk scoring algorithm that provides timely and granular assessments for the clinical acuity of ward patients based on their (temporal) lab tests and vital signs; the proposed…

Artificial Intelligence · Computer Science 2016-10-28 Ahmed M. Alaa , Jinsung Yoon , Scott Hu , Mihaela van der Schaar

Log-symmetric regression models are particularly useful when the response variable is continuous, strictly positive and asymmetric. In this paper, we proposed a class of log-symmetric regression models in the context of correlated errors.…

Methodology · Statistics 2018-10-22 Helton Saulo , Roberto Vila

Modern electronic health records (EHRs) provide data to answer clinically meaningful questions. The growing data in EHRs makes healthcare ripe for the use of machine learning. However, learning in a clinical setting presents unique…

Machine Learning · Computer Science 2019-12-09 Marzyeh Ghassemi , Tristan Naumann , Peter Schulam , Andrew L. Beam , Irene Y. Chen , Rajesh Ranganath

Clinical outcome prediction based on the Electronic Health Record (EHR) plays a crucial role in improving the quality of healthcare. Conventional deep sequential models fail to capture the rich temporal patterns encoded in the longand…

Machine Learning · Computer Science 2019-08-27 Luchen Liu , Haoran Li , Zhiting Hu , Haoran Shi , Zichang Wang , Jian Tang , Ming Zhang

Risk assessment tools in healthcare commonly employ point-based scoring systems that map patients to ordinal risk categories via thresholds. While electronic health record (EHR) data presents opportunities for data-driven optimization of…

Machine Learning · Computer Science 2026-04-20 Fardin Ganjkhanloo , Emmett Springer , Erik H. Hoyer , Daniel L. Young , Kimia Ghobadi

Point processes are stochastic models generating interacting points or events in time, space, etc. Among characteristics of these models, first-order intensity and conditional intensity functions are often considered. We focus on…

Statistics Theory · Mathematics 2023-05-24 Jean-François Coeurjolly , Ismaïla Ba , Achmad Choiruddin

We consider the learning of multi-agent Hawkes processes, a model containing multiple Hawkes processes with shared endogenous impact functions and different exogenous intensities. In the framework of stochastic maximum likelihood…

Machine Learning · Statistics 2018-02-15 Hongteng Xu , Xu Chen , Lawrence Carin

Risk mining technologies seek to find relevant textual extractions that capture entity-risk relationships. However, when high volume data sets are processed, a multitude of relevant extractions can be returned, shifting the focus to how…

Computation and Language · Computer Science 2019-09-24 Berk Ekmekci , Eleanor Hagerman , Blake Howald

Prognostication for lung cancer, a leading cause of mortality, remains a complex task, as it needs to quantify the associations of risk factors and health events spanning a patient's entire life. One challenge is that an individual's…

Machine Learning · Statistics 2025-08-28 Stephen Salerno , Yi Li

One of the key challenges when developing a predictive model is the capability to describe the domain knowledge and the cause-effect relationships in a simple way. Decision rules are a useful and important methodology in this context,…

Machine Learning · Computer Science 2021-10-19 Francisco Valente , Jorge Henriques , Simão Paredes , Teresa Rocha , Paulo de Carvalho , João Morais

Missingness in variables that define study eligibility criteria is a seldom addressed challenge in electronic health record (EHR)-based settings. It is typically the case that patients with incomplete eligibility information are excluded…

We develop a personalized real time risk scoring algorithm that provides timely and granular assessments for the clinical acuity of ward patients based on their (temporal) lab tests and vital signs. Heterogeneity of the patients population…

Machine Learning · Computer Science 2016-05-04 Ahmed M. Alaa , Jinsung Yoon , Scott Hu , Mihaela van der Schaar

Critically ill patients in regular wards are vulnerable to unanticipated adverse events which require prompt transfer to the intensive care unit (ICU). To allow for accurate prognosis of deteriorating patients, we develop a novel…

Machine Learning · Computer Science 2017-05-16 Ahmed M. Alaa , Scott Hu , Mihaela van der Schaar

The problem of finding the expected value of a statistic of a locally stable point process in a bounded region is addressed. We propose an adaptive importance sampling for solving the problem. In our proposal, we restrict the importance…

Machine Learning · Statistics 2025-03-04 Hee-Geon Kang , Sunggon Kim

The large amount of time clinicians spend sifting through patient notes and documenting in electronic health records (EHRs) is a leading cause of clinician burnout. By proactively and dynamically retrieving relevant notes during the…

Information Retrieval · Computer Science 2023-08-17 Sharon Jiang , Shannon Shen , Monica Agrawal , Barbara Lam , Nicholas Kurtzman , Steven Horng , David Karger , David Sontag

The integration of physiological computing into mixed-initiative human-robot interaction systems offers valuable advantages in autonomous task allocation by incorporating real-time features as human state observations into the…

The objective of this work is to develop an Electronic Medical Record (EMR) data processing tool that confers clinical context to Machine Learning (ML) algorithms for error handling, bias mitigation and interpretability. We present…

Research is a tertiary priority in the EHR, where the priorities are patient care and billing. Because of this, the data is not standardized or formatted in a manner easily adapted to machine learning approaches. Data may be missing for a…

Machine Learning · Computer Science 2017-07-25 Brett K. Beaulieu-Jones

The log-likelihood of a generative model often involves both positive and negative terms. For a temporal multivariate point process, the negative term sums over all the possible event types at each time and also integrates over all the…

Machine Learning · Computer Science 2020-11-03 Hongyuan Mei , Tom Wan , Jason Eisner

We investigate applications of deep neural networks to a point process having an intensity with mixing covariates processes as input. Our generic model includes Cox-type models and marked point processes as well as multivariate point…

Statistics Theory · Mathematics 2025-04-23 Yoshihiro Gyotoku , Ioane Muni Toke , Nakahiro Yoshida
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