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High-throughput omics profiling advancements have greatly enhanced cancer patient stratification. However, incomplete data in multi-omics integration presents a significant challenge, as traditional methods like sample exclusion or…

Genomics · Quantitative Biology 2024-01-17 Shihao Ma , Andy G. X. Zeng , Benjamin Haibe-Kains , Anna Goldenberg , John E Dick , Bo Wang

Integrated principal components analysis, or iPCA, is an unsupervised learning technique for grouped vector data recently defined by Tang and Allen. Like PCA, iPCA computes new axes that best explain the variance of the data, but iPCA is…

Statistics Theory · Mathematics 2023-07-04 Cole Franks , Visu Makam

The problem of complex data analysis is a central topic of modern statistical science and learning systems and is becoming of broader interest with the increasing prevalence of high-dimensional data. The challenge is to develop statistical…

Machine Learning · Statistics 2018-03-05 Faicel Chamroukhi , Hien D. Nguyen

Joint analysis of multiple phenotypes can increase statistical power in genetic association studies. Principal component analysis, as a popular dimension reduction method, especially when the number of phenotypes is high-dimensional, has…

Applications · Statistics 2018-06-18 Zhonghua Liu , Xihong Lin

It becomes an interesting problem to identify subgroup structures in data analysis as populations are probably heterogeneous in practice. In this paper, we consider M-estimators together with both concave and pairwise fusion penalties,…

Methodology · Statistics 2020-05-04 Chao Cheng , Xingdong Feng

Multivariate data are typically represented by a rectangular matrix (table) in which the rows are the objects (cases) and the columns are the variables (measurements). When there are many variables one often reduces the dimension by…

Methodology · Statistics 2021-01-13 Mia Hubert , Peter J. Rousseeuw , Wannes Van den Bossche

With the advancement of high-throughput biotechnologies, we increasingly accumulate biomedical data about diseases, especially cancer. There is a need for computational models and methods to sift through, integrate, and extract new…

Quantitative Methods · Quantitative Biology 2020-07-03 Thomas Gaudelet , Noel Malod-Dognin , Natasa Przulj

Distributed algorithms and theories are called for in this era of big data. Under weaker local signal-to-noise ratios, we improve upon the celebrated one-round distributed principal component analysis (PCA) algorithm designed in the spirit…

Methodology · Statistics 2025-07-01 ZeYu Li , Xinsheng Zhang , Wang Zhou

Graph-based multi-view clustering aiming to obtain a partition of data across multiple views, has received considerable attention in recent years. Although great efforts have been made for graph-based multi-view clustering, it remains a…

Computer Vision and Pattern Recognition · Computer Science 2022-11-11 Yiming Wang , Dongxia Chang , Zhiqiang Fu , Yao Zhao

Multi-view data are becoming common in real-world modeling tasks and many multi-view data clustering algorithms have thus been proposed. The existing algorithms usually focus on the cooperation of different views in the original space but…

Machine Learning · Computer Science 2019-08-14 Zhaohong Deng , Ruixiu Liu , Te Zhang , Peng Xu , Kup-Sze Choi , Bin Qin , Shitong Wang

Data comes in many forms. From a shallow perspective, they can be viewed as being either in structured (e.g., as a relation, as key-value pairs) or unstructured (e.g., text, image) formats. So far, machines have been fairly good at…

Computation and Language · Computer Science 2026-03-31 Md Ataur Rahman , Dimitris Sacharidis , Oscar Romero , Sergi Nadal

Graph-based multi-view clustering has achieved better performance than most non-graph approaches. However, in many real-world scenarios, the graph structure of data is not given or the quality of initial graph is poor. Additionally,…

Machine Learning · Computer Science 2022-09-23 Erlin Pan , Zhao Kang

In many settings, we have multiple data sets (also called views) that capture different and overlapping aspects of the same phenomenon. We are often interested in finding patterns that are unique to one or to a subset of the views. For…

Machine Learning · Computer Science 2015-07-15 Rong Ge , James Zou

Principal component analysis (PCA) is one of the most popular dimension reduction techniques in statistics and is especially powerful when a multivariate distribution is concentrated near a lower-dimensional subspace. Multivariate extreme…

Methodology · Statistics 2025-07-15 Felix Reinbott , Anja Janßen

Multivariate binary data is becoming abundant in current biological research. Logistic principal component analysis (PCA) is one of the commonly used tools to explore the relationships inside a multivariate binary data set by exploiting the…

Methodology · Statistics 2020-10-15 Yipeng Song , Johan A. Westerhuis , Age K. Smilde

In this paper, we develop an algorithm for federated principal component analysis (PCA) with emphases on both communication efficiency and data privacy. Generally speaking, federated PCA algorithms based on direct adaptations of classic…

Optimization and Control · Mathematics 2024-10-29 Lei Wang , Xin Liu , Yin Zhang

Principal component analysis (PCA) is a fundamental tool for analyzing multivariate data. Here the focus is on dimension reduction to the principal subspace, characterized by its projection matrix. The classical principal subspace can be…

Methodology · Statistics 2026-05-29 Fabio Centofanti , Mia Hubert , Peter J. Rousseeuw

Principal Component Analysis (PCA) is a very successful dimensionality reduction technique, widely used in predictive modeling. A key factor in its widespread use in this domain is the fact that the projection of a dataset onto its first…

Machine Learning · Statistics 2017-05-19 Xianghui Luo , Robert J. Durrant

There are a multitude of methods to perform multi-set correlated component analysis (MCCA), including some that require iterative solutions. The methods differ on the criterion they optimize and the constraints placed on the solutions. This…

Machine Learning · Statistics 2018-02-13 Lucas C Parra

Efficient representations of data are essential for processing, exploration, and human understanding, and Principal Component Analysis (PCA) is one of the most common dimensionality reduction techniques used for the analysis of large,…

Computation · Statistics 2023-11-06 Olga Dorabiala , Aleksandr Aravkin , J. Nathan Kutz