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Recent years have seen a phenomenal rise in performance and applications of transformer neural networks. The family of transformer networks, including Bidirectional Encoder Representations from Transformer (BERT), Generative Pretrained…

Machine Learning · Computer Science 2023-07-18 Krishna Teja Chitty-Venkata , Sparsh Mittal , Murali Emani , Venkatram Vishwanath , Arun K. Somani

Phylogenetics is the study of the evolutionary relationships between organisms. One of the main challenges in the field is to take biological data for a group of organisms and to infer an evolutionary tree, a graph that represents these…

Populations and Evolution · Quantitative Biology 2019-06-05 Elizabeth Gross , Colby Long , Joseph Rusinko

Descriptive and inferential social network analysis has become common in public administration studies of network governance and management. A large literature has developed in two broad categories: antecedents of network structure, and…

Social and Information Networks · Computer Science 2024-09-02 Travis A. Whetsell , Michael D. Siciliano

A system level view of cellular processes for human and several organisms can be cap- tured by analyzing molecular interaction networks. A molecular interaction network formed of differentially expressed genes and their interactions helps…

Molecular Networks · Quantitative Biology 2016-11-09 Jeethu V. Devasia , Priya Chandran

Statistical inference of genetic regulatory networks is essential for understanding temporal interactions of regulatory elements inside the cells. For inferences of large networks, identification of network structure is typical achieved…

Quantitative Methods · Quantitative Biology 2008-04-07 Heng Lian

Real-world information networks are increasingly occurring across various disciplines including online social networks and citation networks. These network data are generally characterized by sparseness, nonlinearity and heterogeneity…

Machine Learning · Computer Science 2021-09-17 Amina Amara , Mohamed Ali Hadj Taieb , Mohamed Ben Aouicha

Gaussian Graphical Models (GGMs) have been used to construct genetic regulatory networks where regularization techniques are widely used since the network inference usually falls into a high-dimension-low-sample-size scenario. Yet, finding…

Methodology · Statistics 2013-04-24 Shuang Li , Li Hsu , Jie Peng , Pei Wang

We consider the problem of identifying the topology of a weighted, undirected network $\mathcal G$ from observing snapshots of multiple independent consensus dynamics. Specifically, we observe the opinion profiles of a group of agents for a…

Social and Information Networks · Computer Science 2019-02-12 Santiago Segarra , Michael T. Schaub , Ali Jadbabaie

Despite theoretical advantages, causal methods for Gene Regulatory Network (GRN) inference from single-cell RNA-seq data consistently fail to match or outperform correlation-based baselines in many realistic benchmarks, a persistent puzzle…

Machine Learning · Computer Science 2026-05-07 Miguel Fernandez-de-Retana , Ruben Sanchez-Corcuera , Unai Zulaika , Aritz Bilbao-Jayo , Aitor Almeida

Probabilistic inference is a fundamental task in modern machine learning. Recent advances in tensor network (TN) contraction algorithms have enabled the development of better exact inference methods. However, many common inference tasks in…

Machine Learning · Computer Science 2024-09-10 Martin Roa-Villescas , Xuanzhao Gao , Sander Stuijk , Henk Corporaal , Jin-Guo Liu

Inference of the network structure (e.g., routing topology) and dynamics (e.g., link performance) is an essential component in many network design and management tasks. In this paper we propose a new, general framework for analyzing and…

Networking and Internet Architecture · Computer Science 2019-11-13 Jian Ni , Sekhar Tatikonda

Inferring the network topology from the dynamics is a fundamental problem with wide applications in geology, biology and even counter-terrorism. Based on the propagation process, we present a simple method to uncover the network topology.…

Physics and Society · Physics 2013-11-21 An Zeng

Constructing gene interaction networks (GINs) from high-throughput gene expression data is an important and challenging problem in systems biology. Existing algorithms produce networks that either have undirected and unweighted edges, or…

Genomics · Quantitative Biology 2016-03-15 Nitin Kumar Singh , M. Eren Ahsen , Shiva Mankala , Hyun-Seok Kim , Michael A. White , M. Vidyasagar

Graphs are a powerful data structure to represent relational data and are widely used to describe complex real-world data structures. Probabilistic Graphical Models (PGMs) have been well-developed in the past years to mathematically model…

Artificial Intelligence · Computer Science 2023-01-31 Chenqing Hua , Sitao Luan , Qian Zhang , Jie Fu

Gene expression-based heterogeneity analysis has been extensively conducted. In recent studies, it has been shown that network-based analysis, which takes a system perspective and accommodates the interconnections among genes, can be more…

Methodology · Statistics 2023-08-09 Rong Li , Qingzhao Zhang , Shuangge Ma

Recent genomic and bioinformatic advances have motivated the development of numerous random network models purporting to describe graphs of biological, technological, and sociological origin. The success of a model has been evaluated by how…

Molecular Networks · Quantitative Biology 2007-05-23 Manuel Middendorf , Etay Ziv , Carter Adams , Jen Hom , Robin Koytcheff , Chaya Levovitz , Gregory Woods , Linda Chen , Chris Wiggins

We introduce a novel gene regulatory network (GRN) inference method that integrates optimal transport (OT) with a deep-learning structural inference model. Advances in next-generation sequencing enable detailed yet destructive gene…

Computational Engineering, Finance, and Science · Computer Science 2024-09-24 Tsz Pan Tong , Aoran Wang , George Panagopoulos , Jun Pang

Gene regulatory network (GRN) inference serves as a cornerstone for deciphering cellular decision-making processes. Early approaches rely exclusively on gene expression data, thus their predictive power remain fundamentally constrained by…

Molecular Networks · Quantitative Biology 2025-11-25 Rui Peng , Yuchen Lu , Qichen Sun , Yuxing Lu , Chi Zhang , Ziru Liu , Jinzhuo Wang

Graph Neural Networks (GNNs) are widely used in many modern applications, necessitating explanations for their decisions. However, the complexity of GNNs makes it difficult to explain predictions. Even though several methods have been…

Machine Learning · Computer Science 2022-11-04 Tien-Cuong Bui , Van-Duc Le , Wen-Syan Li , Sang Kyun Cha

While machine learning is traditionally a resource intensive task, embedded systems, autonomous navigation, and the vision of the Internet of Things fuel the interest in resource-efficient approaches. These approaches aim for a carefully…

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