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Fetal Magnetic Resonance Imaging at low field strengths is emerging as an exciting direction in perinatal health. Clinical low field (0.55T) scanners are beneficial for fetal imaging due to their reduced susceptibility-induced artefacts,…
Tissue mechanics--stiffness, density and impedance contrast--are broadly informative biomarkers across diseases, yet routine CT, MRI, and B-mode ultrasound rarely quantify them directly. While ultrasound tomography (UT) is intrinsically…
Purpose: To demonstrate an ultrashort echo time magnetic resonance fingerprinting (UTE-MRF) method that can simultaneously quantify tissue relaxometries for muscle and bone in musculoskeletal systems and tissue components in brain and…
Purpose: To develop a framework to reconstruct large-scale volumetric dynamic MRI from rapid continuous and non-gated acquisitions, with applications to pulmonary and dynamic contrast enhanced (DCE) imaging. Theory and Methods: The problem…
Parallel imaging is ubiquitous in MRI, enabling diverse applications such as ultra-high-resolution functional and quantitative imaging with greater temporal resolution or reduced scan times respectively. Successful unfolding is contingent…
A sparse modeling approach is proposed for analyzing scanning tunneling microscopy topography data, which contains numerous peaks corresponding to surface atoms. The method, based on the relevance vector machine with $\mathrm{L}_1$…
Quantitative Magnetic Resonance Imaging (MRI) is based on a two-steps approach: estimation of the magnetic moments distribution inside the body, followed by a voxel-by-voxel quantification of the human tissue properties. This splitting…
Purpose: To develop a motion-robust and geometrically-accurate quantitative CEST approach using radial k-space sampling, locally low-rank reconstruction and neural network quantification. Methods: The acquisition schedule was generated via…
Statistical shape modeling (SSM) is an essential tool for analyzing variations in anatomical morphology. In a typical SSM pipeline, 3D anatomical images, gone through segmentation and rigid registration, are represented using…
Magnetic Resonance Imaging (MRI) of hard biological tissues is challenging due to the fleeting lifetime and low strength of their response to resonant stimuli, especially at low magnetic fields. Consequently, the impact of MRI on some…
We propose a new objective numerical figure of merit to aid in the evaluation and comparison of tissue-selective images generated from dual-energy radiography systems. A metric is developed through identification of the requirements of a…
Quantitative ultrasound, e.g., speed-of-sound (SoS) in tissues, provides information about tissue properties that have diagnostic value. Recent studies showed the possibility of extracting SoS information from pulse-echo ultrasound raw data…
Quantitative ultrasound (QUS) methods provide a promising framework that can non-invasively and inexpensively be used to predict or assess the tumour response to cancer treatment. The first step in using the QUS methods is to select a…
In this paper we estimate the dynamic parameters of a time-varying coefficient model through radial kernel functions in the context of a longitudinal study. Our proposal is based on a linear combination of weighted kernel functions…
Quantitative mapping of magnetic resonance (MR) parameters have been shown as valuable methods for improved assessment of a range of diseases. Due to the need to image an anatomic structure multiple times, parameter mapping usually requires…
Purpose: To develop a rapid, high-resolution and distortion-free technique for simultaneous water-fat separation, $R_{2}^{*}$ and $B_{0}$ mapping of the fetal brain at 3T. Methods: A 2D multi-echo radial FLASH sequence with blip gradients…
Resonant ultrasound spectroscopy (RUS) is a powerful technique for measuring the full elastic tensor of a given material in a single experiment. Previously, this technique was limited to regularly-shaped samples such as rectangular…
Purpose: To achieve automatic hyperparameter estimation for the joint recovery of quantitative MR images, we propose a Bayesian formulation of the reconstruction problem that incorporates the signal model. Additionally, we investigate the…
This paper presents an iterative inversion algorithm for computed tomography image reconstruction that performs well in terms of accuracy and speed using limited data. The computational method combines an image domain technique and…
Time delay estimation (TDE) between two radio-frequency (RF) frames is one of the major steps of quasi-static ultrasound elastography, which detects tissue pathology by estimating its mechanical properties. Regularized optimization-based…