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Modeling biological soft tissue is complex in part due to material heterogeneity. Microstructural patterns, which play a major role in defining the mechanical behavior of these tissues, are both challenging to characterize, and difficult to…

Machine Learning · Computer Science 2022-07-19 Hiba Kobeissi , Saeed Mohammadzadeh , Emma Lejeune

Fibre-reinforced hydrogels are promising materials for biomedical applications due to their strength, toughness, and tunability. However, it remains unclear how to design fibre-reinforced hydrogels for use in specific applications due to…

Soft Condensed Matter · Physics 2025-03-26 Matthew G. Hennessy , Tom Shearer , Axel C. Moore

Over times shorter than that required for relaxation of enthalpy, a liquid can exhibit striking heterogeneities. The picture of these heterogeneities is complex with transient patches of rigidity, irregular yet persistent, intersected by…

Soft Condensed Matter · Physics 2010-09-30 Peter Harrowell

We propose a three dimensional mechanical model of embryonic tissue dynamics. Mechanically coupled adherent cells are represented as particles interconnected with elastic beams which can exert non-central forces and torques. Tissue…

Biological Physics · Physics 2015-06-22 Andras Czirok , Dona Greta Isai

Observations of glassy dynamics in experiments on confluent cellular tissue have inspired a wealth of computational and theoretical research to model their emergent collective behavior. Initial studies of the physical properties of several…

Soft Condensed Matter · Physics 2024-09-04 Helen S. Ansell , Chengling Li , Daniel M. Sussman

Granular materials are of critical interest to many robotic tasks in planetary science, construction, and manufacturing. However, the dynamics of granular materials are complex and often computationally very expensive to simulate. We…

Robotics · Computer Science 2023-06-05 David Millard , Daniel Pastor , Joseph Bowkett , Paul Backes , Gaurav S. Sukhatme

Granular materials are ubiquitous in nature and industry; their mechanical behavior has been of academic and engineering interest for centuries. One of the reasons for their rather complex mechanical behavior is that stresses exerted on a…

Soft Condensed Matter · Physics 2024-03-26 Chandan Shakya , Jasper van der Gucht , Joshua A. Dijksman

Ferrogels and magnetoelastomers are composite materials obtained by embedding magnetic particles of mesoscopic size in a crosslinked polymeric matrix. They combine the reversible elastic deformability of polymeric materials with the high…

Due to current technological challenges, including the complexity of precise control, low long-term survival and success rates, difficulty in maintaining function over extended periods, and high energy consumption, the construction of…

Chemical Physics · Physics 2024-08-19 Hanqing Dai , Wenqing Dai , Yuanyuan Chen , Wanlu Zhang , Yimeng Wang , Ruiqian Guo , Guoqi Zhang

Porous and flexible actuating materials are important in the development of smart systems. We report here a facile method to prepare scalable, flexible actuating porous membranes based on a poly(ionic liquid)-modified tissue paper. The…

Applied Physics · Physics 2017-05-23 Huijuan Lin , Jiang Gong , Han Miao , Ryan Guterman , Haojie Song , Qiang Zhao , John W. C. Dunlop , Jiayin Yuan

The global increase in materials consumption calls for innovative materials, with tailored performance and multi-functionality, that are environmentally sustainable. Composites from renewable resources offer solutions to fulfil these…

Applied Physics · Physics 2019-09-05 Eleftheria Roumeli , Luca Bonanomi , Rodinde Hendrickx , Katherine Rinaldi , Chiara Daraio

Biological cells are built up from many different constituents of varying size and stiffness which all contribute to the cell's mechanical properties. Despite this heterogeneity, in the analysis of experimental measurements such as atomic…

Biological Physics · Physics 2023-05-18 Sebastian Wohlrab , Sebastian J. Müller , Stephan Gekle

Cells control fluid flows with a spatial and temporal precision that far exceeds the capabilities of current microfluidic technologies. Cells achieve this superior spatio-temporal control by harnessing dynamic networks of cytoskeleton and…

Soft Condensed Matter · Physics 2025-05-26 Fan Yang , Shichen Liu , Heun Jin Lee , Rob Phillips , Matt Thomson

Flexible photonics offers the possibility to realize wearable sensors by bridging the advantages of flexible materials and photonic sensing elements. Recently, optical resonators have emerged as a tool to improve its over sensitivity by…

Optics · Physics 2023-12-22 Ningyuan Nie , Yu-Cheng Chen

Incorporating nanomaterials into hydrogels allows for the creation of versatile materials with properties that can be precisely tailored by manipulating their nanoscale structures, leading to a wide range of bulk properties. Investigating…

Soft Condensed Matter · Physics 2024-11-13 Irfan Khan , Snigdharani Panda , Sugam Kumar , Sunita Srivastava

Natural systems integrate the work of many sub-units (cells) toward a large-scale unified goal (morphological and behavioral), which can counteract the effects of unexpected experiences, damage, or simply changes in tasks demands. In this…

The dynamics of cellular aggregates is driven by the interplay of mechanochemical processes and cellular activity. Although deterministic models may capture mechanical features, local chemical fluctuations trigger random cell responses,…

Soft Condensed Matter · Physics 2024-01-17 Ana Carpio , Elena Cebrian

Soft biological tissues exhibit a remarkable resilience to large mechanical loads, a property which is associated with the strain stiffening capability of the biopolymer networks that structurally support the tissues. Yet, recent studies…

Soft Condensed Matter · Physics 2024-03-19 Jake Song , Elad Deiss-Yehiely , Serra Yesilata , Gareth H. McKinley

Implantable hydrogels should ideally possess mechanical properties matched to the surrounding tissues to enable adequate mechanical function while regeneration occurs. This can be challenging, especially when degradable systems with high…

Tissues and Organs · Quantitative Biology 2024-03-19 Michael Phillips , Giuseppe Tronci , Christopher M. Pask , Stephen J. Russell

In analogy with classic rigidity problems of networks and frames, the elastic properties of hydrogels made of DNA nanostars (DNAns) are expected to strongly depend on the precise geometry of their building blocks. However, it is currently…

Soft Condensed Matter · Physics 2025-02-03 Yair Augusto Gutierrez Fosado