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AlphaFold has achieved groundbreaking advancements in protein structure prediction, exerting profound influence across biology, medicine, and drug discovery. However, its reliance on multiple sequence alignment (MSA) is inherently…

Quantum Physics · Physics 2025-06-03 Rong Chen , Quan-Xin Mei , Wen-Ding Zhao , Lin Yao , Hao-Xiang Yang , Shun-Yao Zhang , Jiao Chen , Hong-Lin Li

Collaborative filtering models generally perform better than content-based filtering models and do not require careful feature engineering. However, in the cold-start scenario collaborative information may be scarce or even unavailable,…

Information Retrieval · Computer Science 2022-05-13 Artyom Nikitin , Andrei Chertkov , Rafael Ballester-Ripoll , Ivan Oseledets , Evgeny Frolov

In this paper, we develop a way to encode several NP-Complete problems in Abstract Argumentation to Quadratic Unconstrained Binary Optimization (QUBO) problems. In this form, a solution for a QUBO problem involves minimizing a quadratic…

Quantum Physics · Physics 2024-09-10 Marco Baioletti , Francesco Santini

The QED-C suite of Application-Oriented Benchmarks provides the ability to gauge performance characteristics of quantum computers as applied to real-world applications. Its benchmark programs sweep over a range of problem sizes and inputs,…

Machine Learning (ML) has been widely applied across numerous domains due to its ability to automatically identify informative patterns from data for various tasks. The availability of large-scale data and advanced computational power…

Quantitative investment aims to maximize the return and minimize the risk in a sequential trading period over a set of financial instruments. Recently, inspired by rapid development and great potential of AI technologies in generating…

General Finance · Quantitative Finance 2020-09-24 Xiao Yang , Weiqing Liu , Dong Zhou , Jiang Bian , Tie-Yan Liu

The Quantum Alternating Operator Ansatz is a generalization of the Quantum Approximate Optimization Algorithm (QAOA) designed for finding approximate solutions to combinatorial optimization problems with hard constraints. In this paper, we…

Quantum Physics · Physics 2021-07-02 Jeremy Cook , Stephan Eidenbenz , Andreas Bärtschi

Clustering financial assets based on return correlations is a fundamental task in portfolio optimization and statistical arbitrage. However, classical clustering methods often fall short when dealing with signed correlation structures,…

Quantum Physics · Physics 2026-02-25 Shivam Sharma , Supreeth Mysore Venkatesh , Pushkin Kachroo

Classical program analysis techniques, such as abstract interpretation and symbolic execution, are essential for ensuring software correctness, optimizing performance, and enabling compiler optimizations. However, these techniques face…

Quantum Physics · Physics 2025-10-14 Yicheng Guang , Pietro Zanotta , Kai Zhou , Yueqi Chen , Ramin Ayanzadeh

Leveraging quantum computers for optimization problems holds promise across various application domains. Nevertheless, utilizing respective quantum computing solvers requires describing the optimization problem according to the Quadratic…

Quantum Physics · Physics 2025-10-15 Deborah Volpe , Nils Quetschlich , Mariagrazia Graziano , Giovanna Turvani , Robert Wille

When trying to use quantum-enhanced methods for optimization problems, the sheer number of options inhibits its adoption by industrial end users. Expert knowledge is required for the formulation and encoding of the use case, the selection…

Quantum Physics · Physics 2025-05-27 Benedikt Poggel , Xiomara Runge , Adelina Bärligea , Jeanette Miriam Lorenz

Hybrid quantum-classical algorithms hold great promise for solving quantum control problems on near-term quantum computers. In this work, we employ the hybrid framework that integrates digital quantum simulation with classical optimization…

Quantum Physics · Physics 2025-07-01 Tangyou Huang , Jing-Jun Zhu , Zhong-Yi Ni

The quantum internet holds transformative potential for global communication by harnessing the principles of quantum information processing. Despite significant advancements in quantum communication technologies, the efficient distribution…

Quantum Physics · Physics 2025-03-06 Lamarana Jallow , Majid Iqbal Khan

Quantum convolutional neural networks (QCNNs) represent a promising approach in quantum machine learning, paving new directions for both quantum and classical data analysis. This approach is particularly attractive due to the absence of the…

Quantum Physics · Physics 2025-08-06 Changwon Lee , Israel F. Araujo , Dongha Kim , Junghan Lee , Siheon Park , Ju-Young Ryu , Daniel K. Park

Quadratic Unconstrained Binary Optimization (QUBO) is a generic technique to model various NP-hard Combinatorial Optimization problems (CO) in the form of binary variables. Ising Hamiltonian is used to model the energy function of a system.…

Machine Learning · Computer Science 2023-12-13 Redwan Ahmed Rizvee , Raheeb Hassan , Md. Mosaddek Khan

Quantum annealing has emerged as a powerful tool for solving combinatorial optimization problems efficiently, making use of the principles of quantum mechanics. Companies are increasingly investing in the market of quantum computers,…

Quantum Physics · Physics 2025-09-29 Lorenzo Mazzei , Giada Beccari , Mirko Laruina , Marco Cococcioni

Quantum Approximate Optimization Algorithm (QAOA) is one of the most short-term promising quantum-classical algorithm to solve unconstrained combinatorial optimization problems. It alternates between the execution of a parametrized quantum…

Optimization and Control · Mathematics 2024-11-18 Camille Grange , Marion Lavignac , Valentina Pozzoli , Eric Bourreau

Modular quantum computing architectures are a promising alternative to monolithic QPU (Quantum Processing Unit) designs for scaling up quantum devices. They refer to a set of interconnected QPUs or cores consisting of tightly coupled…

It is hoped that quantum computers will offer advantages over classical computers for combinatorial optimization. Here, we introduce a feedback-based strategy for quantum optimization, where the results of qubit measurements are used to…

Quantum Physics · Physics 2023-01-05 Alicia B. Magann , Kenneth M. Rudinger , Matthew D. Grace , Mohan Sarovar

Alternative Current Optimal Power Flow (AC-OPF) is essential for efficient power system planning and real-time operation but remains an NP-hard and non-convex optimization problem with significant computational challenges. This paper…

Systems and Control · Electrical Eng. & Systems 2025-03-03 Ze Hu , Ziqing Zhu , Linghua Zhu , Xiang Wei , Siqi Bu , Ka Wing Chan