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Heterogeneous high-performance computing (HPC) systems offer novel architectures which accelerate specific workloads through judicious use of specialized coprocessors. A promising architectural approach for future scientific computations is…

As quantum computing hardware systems continue to advance, the research and development of performant, scalable, and extensible software architectures, languages, models, and compilers is equally as important in order to bring this novel…

Quantum Physics · Physics 2024-06-06 Daniel Claudino , Alexander J. McCaskey , Dmitry I. Lyakh

Recent computations involving quantum processing units (QPUs) have demonstrated a series of challenges inherent to hybrid classical-quantum programming, compilation, execution, and verification and validation. Despite considerable progress,…

Quantum Physics · Physics 2018-05-24 Alexander McCaskey , Eugene Dumitrescu , Dmitry Liakh , Travis Humble

This paper presents a comprehensive software stack architecture for integrating quantum computing (QC) capabilities with High-Performance Computing (HPC) environments. While quantum computers show promise as specialized accelerators for…

Noisy gate-model quantum processing units (QPUs) are currently available from vendors over the cloud, and digital quantum programming approaches exist to run low-depth circuits on physical hardware. These digital representations are…

Quantum Physics · Physics 2020-03-28 Thien Nguyen , Alexander McCaskey

The connection and eventual integration of High-Performance Computing (HPC) with Quantum Computing (QC) represents a transformative advancement in computational technology, promising significant enhancements in solving complex, previously…

The technology of Quantum Computing (QC) is continuously evolving, as researchers explore new technologies and the public gains access to quantum computers with an increasing number of qubits. In addition, the research community and…

Quantum Computing (QC) refers to an emerging paradigm that inherits and builds with the concepts and phenomena of Quantum Mechanic (QM) with the significant potential to unlock a remarkable opportunity to solve complex and computationally…

Quantum computing promises potential for science and industry by solving certain computationally complex problems faster than classical computers. Quantum computing systems evolved from monolithic systems towards modular architectures…

Quantum Physics · Physics 2023-08-15 Nishant Saurabh , Shantenu Jha , Andre Luckow

High-performance computing (HPC) has evolved over decades through multiple architectural transitions, from vector supercomputers to massively parallel CPU clusters and GPU-accelerated systems, continuously expanding the frontier of…

Quantum Physics · Physics 2026-04-23 Suman Raj , Siva Sai , Yogesh Simmhan , Kyle Chard , Rajkumar Buyya

This paper introduces a vision for Quantum Software Development lifecycle, proposing a hybrid full-stack iterative model that integrates quantum and classical computing. Addressing the current challenges in Quantum Computing (QC) such as…

Software Engineering · Computer Science 2025-04-09 Arif Ali Khan , Davide Taibi , Muhammad Azeem Akbar

Quantum computers have demonstrated utility in simulating quantum systems beyond brute-force classical approaches. As the community builds on these demonstrations to explore using quantum computing for applied research, algorithms and…

Quantum computing is rapidly progressing from theoretical promise to practical implementation, offering significant computational advantages for tasks in optimization, simulation, cryptography, and machine learning. However, its integration…

Quantum computers are often treated as experimental add-ons that are loosely coupled to classical infrastructure through high-level interpreted languages and cloud-like orchestration. However, future deployments in both, high-performance…

Quantum Physics · Physics 2025-07-28 Ralf Ramsauer , Wolfgang Mauerer

Quantum computing (QC) is anticipated to provide a speedup over classical HPC approaches for specific problems in optimization, simulation, and machine learning. With the advances in quantum computing toward practical applications, the need…

Quantum Physics · Physics 2022-10-26 Jernej Rudi Finžgar , Philipp Ross , Leonhard Hölscher , Johannes Klepsch , Andre Luckow

We define some of the programming and system-level challenges facing the application of quantum processing to high-performance computing. Alongside barriers to physical integration, prominent differences in the execution of quantum and…

Quantum Physics · Physics 2017-12-06 Keith A. Britt , Fahd A. Mohiyaddin , Travis S. Humble

Quantum computing (QC) holds the potential to solve classically intractable problems. Although there has been significant progress towards the availability of quantum hardware, a software infrastructure to integrate them is still missing.…

Quantum Physics · Physics 2025-06-17 Zhaobin Zhu , Cedric Gaberle , Sarah M. Neuwirth , Thomas Lippert , Manpreet S. Jattana

In the expanding field of Quantum Computing (QC), efficient and seamless integration of QC and high performance computing (HPC) elements (e.g., quantum hardware, classical hardware, and software infrastructure on both sides) plays a crucial…

Quantum Physics · Physics 2023-09-08 Philipp Seitz , Amr Elsharkawy , Xiao-Ting Michelle To , Martin Schulz

Quantum computing (QC) introduces a novel mode of computation with the possibility of greater computational power that remains to be exploited - presenting exciting opportunities for high performance computing (HPC) applications. However,…

Quantum computing vendors are beginning to open up application programming interfaces for direct pulse-level quantum control. With this, programmers can begin to describe quantum kernels of execution via sequences of arbitrary pulse shapes.…

Quantum Physics · Physics 2020-06-05 Thien Nguyen , Anthony Santana , Alexander McCaskey
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