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Aims. We aim to improve a previous model for the prediction of column densities and deuterium fractions of non- and singly deuterated methanol. Thereby, we try to identify crucial chemical and physical parameters, for which the study of…

Astrophysics of Galaxies · Physics 2023-12-20 W. Riedel , O. Sipilä , E. Redaelli , P. Caselli , A. I. Vasyunin , F. Dulieu , N. Watanabe

Methanol is a key species in astrochemistry since it is the most abundant organic molecule in the ISM and is thought to be the mother molecule of many complex organic species. Estimating the deuteration of methanol around young protostars…

Deuterium fractionation, as studied through mono-deuterated methanol, is frequently used as a diagnostic tool to trace the physical conditions and chemical evolution of interstellar sources. This study investigates methanol deuteration in…

Solar and Stellar Astrophysics · Physics 2025-06-10 Shaoshan Zeng , Jae-Hong Jeong , Takahiro Oyama , Jeong-Eun Lee , Yao-Lun Yang , Nami Sakai

Dendritic cells (DCs) display the unique ability to activate naive T cells and to initiate primary T cell responses revealed in DC-T cell alloreactions. DCs frequently operate under stress conditions. Oxidative stress enhances the…

The study of compounds with antioxidant capabilities is of great interest to the scientific community, as it has implications in several areas, from Agricultural Sciences to Biological Sciences, including Food Engineering, Medicine and…

The effects of purification methods and its hypolipidemic function on the total flavonoids of Aurea Helianthus flower were investigated. Liquid-liquid extraction of ethanol extract from Aurea Helianthus flower was carried out by using…

Biomolecules · Quantitative Biology 2019-07-01 Hyon-il Ri , Chol-song Kim , Un-hak Pak , Myong-su Kang , Tae-mun Kim

Cold cores are an early step of star formation, characterized by densities > 10$^4$ cm$^{-3}$, low temperatures (< 15 K), and very low external UV radiation. We investigate the physico-chemical processes at play to tracing the origin of…

Astrophysics of Galaxies · Physics 2023-01-04 A. Taillard , V. WakelaM , P. Gratier , E. Dartois , M. Chabot , J. A. Noble , J. V. Keane , A. C. A. Boogert , D. Harsono

Anti-staphylococcal penicillins (ASPs) are recommended as first-line agents in methicillin-susceptible Staphylococcus aureus (MSSA) bacteraemia. Concerns about their safety profile have contributed to the increased use of cefazolin. The…

Reducing antibiotic usage in livestock animals has become an urgent issue worldwide to prevent antimicrobial resistance. Here, abuse of chlortetracycline (CTC), a versatile antibacterial agent, on the performance, blood components, fecal…

Efficient syntheses of some new substituted pyrazoline derivatives linked to substituted benzimidazole scaffold were performed by multistep reaction sequences. All the synthesized compounds were characterized using elemental analysis and…

Biomolecules · Quantitative Biology 2020-05-05 Gopal Krishna Padhy , Jagadeesh Panda , Ajaya Kumar Behera

Quantitative characterization of biophysical alterations caused by viral infection remains at an early stage. In this study, we examined the mechanical response of Vero cells after exposure to an attenuated Measles Vaccine Virus using…

The study of deuteration in pre-stellar cores is important to understand the physical and chemical initial conditions in the process of star formation. In particular, observations toward pre-stellar cores of methanol and deuterated…

Background: Esophageal cancer poses a significant global health challenge, with the incidence of esophageal adenocarcinoma (EAC), a predominant subtype, increasing notably in Western countries. Cathepsins, a family of lysosomal proteolytic…

Tissues and Organs · Quantitative Biology 2025-04-03 Jialin Li , Shaokang Yang , Xinliang Gao , Mingbo Tang , Xiaobo Ma , Suyan Tian , Wei Liu

The interest in milk originating from donkeys is growing worldwide due to its claimed functional and nutritional properties, especially for sensitive population groups, such as infants with cow milk protein allergy. The current study aimed…

Quantitative Methods · Quantitative Biology 2020-09-07 P. Papademas , E. Kamilari , M. Aspri , D. A Anagnostopoulos , P. Mousikos , A. Kamilaris , D. Tsaltas

Neopetrosia exigua has received great attention in natural product chemistry. The diversity of N. exigua constituents has been demonstrated by the continued discovery of novel bioactive metabolites such as antimicrobial metabolites. In this…

Biomolecules · Quantitative Biology 2019-12-12 Ibrahim Majali , Haitham N. Qaralleh , Syed Z. Idid , Shahbudin Saad , Deny Susanti , Osama Y. Althunibat

Recent observations indicate that organic molecules are prevalent towards starless and prestellar cores. Deuteration of these molecules has not been well-studied during the starless phase. Published observations of singly-deuterated…

Astrophysics of Galaxies · Physics 2020-12-02 Hannah E. Ambrose , Yancy L. Shirley , Samantha Scibelli

Dictyostelium discoideum is an ideal organism to test the pathogenicity of Pseudomonas aeruginosa, since its eukaryote nature allows for comparisons to be made to human health. Additionally, D. discoideum naturally feeds on bacteria and has…

Cell Behavior · Quantitative Biology 2018-06-28 Asher Parvu , Katherine Ortiz

Cellular microrheology has shown that cancer cells with high metastatic potential are softer compared to non-tumorigenic normal cells. These findings rely on measuring the apparent Young modulus of whole cells using primarily atomic force…

Biological Physics · Physics 2024-03-19 Marie Dessard , Jean-Baptiste Manneville , Jean-François Berret

The ALMA interferometer, with its unprecedented combination of high-sensitivity and high-angular resolution, allows for (sub-)mm wavelength mapping of protostellar systems at Solar System scales. Astrochemistry has benefited from imaging…

In this research, we investigated the efficacy of Metformin, the most commonly administered type-2 diabetes drug for triple negative breast cancer (TNBC) treatment, due to its various anticancer properties. It is a plant-based bio-compound,…

Biomolecules · Quantitative Biology 2024-04-23 Praveen Sahu , Ignacio G. Camarillo , Pragatheiswar Giri , Raji Sundararajan