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Deep learning models, such as the fully convolutional network (FCN), have been widely used in 3D biomedical segmentation and achieved state-of-the-art performance. Multiple modalities are often used for disease diagnosis and quantification.…

Image and Video Processing · Electrical Eng. & Systems 2019-08-23 Yu Chen , Jiawei Chen , Dong Wei , Yuexiang Li , Yefeng Zheng

Retinal blood vessel segmentation can extract clinically relevant information from fundus images. As manual tracing is cumbersome, algorithms based on Convolution Neural Networks have been developed. Such studies have used small publicly…

Image and Video Processing · Electrical Eng. & Systems 2024-06-24 Jeremiah Fadugba , Patrick Köhler , Lisa Koch , Petru Manescu , Philipp Berens

Existing multi-modal learning methods on fundus and OCT images mostly require both modalities to be available and strictly paired for training and testing, which appears less practical in clinical scenarios. To expand the scope of clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Lehan Wang , Chongchong Qi , Chubin Ou , Lin An , Mei Jin , Xiangbin Kong , Xiaomeng Li

The Segment Anything Model (SAM) has gained popularity as a versatile image segmentation method, thanks to its strong generalization capabilities across various domains. However, when applied to optic disc (OD) and optic cup (OC)…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Jinchen Yu , Yongwei Nie , Fei Qi , Wenxiong Liao , Hongmin Cai

Optical Coherence Tomography (OCT) is a novel and effective screening tool for ophthalmic examination. Since collecting OCT images is relatively more expensive than fundus photographs, existing methods use multi-modal learning to complement…

Image and Video Processing · Electrical Eng. & Systems 2023-08-02 Lehan Wang , Weihang Dai , Mei Jin , Chubin Ou , Xiaomeng Li

Accurate segmentation of the blood vessels of the retina is an important step in clinical diagnosis of ophthalmic diseases. Many deep learning frameworks have come up for retinal blood vessels segmentation tasks. However, the complex…

Image and Video Processing · Electrical Eng. & Systems 2022-04-08 Ting Zhang , Jun Li , Yi Zhao , Nan Chen , Han Zhou , Hongtao Xu , Zihao Guan , Changcai Yang , Lanyan Xue , Riqing Chen , Lifang Wei

Deep learning models have the capacity to fundamentally revolutionize medical imaging analysis, and they have particularly interesting applications in computer-aided diagnosis. We attempt to use deep learning neural networks to diagnose…

Machine Learning · Computer Science 2020-02-24 Rohit Jammula , Vishnu Rajan Tejus , Shreya Shankar

A fundus image usually contains the optic disc, pathologies and other structures in addition to vessels to be segmented. This study proposes a deep network for vessel segmentation, whose architecture is inspired by inception modules. The…

Image and Video Processing · Electrical Eng. & Systems 2019-11-21 Fatmatulzehra Uslu

Accurate retinal vessel segmentation is a challenging problem in color fundus image analysis. An automatic retinal vessel segmentation system can effectively facilitate clinical diagnosis and ophthalmological research. Technically, this…

Image and Video Processing · Electrical Eng. & Systems 2021-03-26 Muyi Sun , Guanhong Zhang

Multiple-surface segmentation in Optical Coherence Tomography (OCT) images is a challenge problem, further complicated by the frequent presence of weak image boundaries. Recently, many deep learning (DL) based methods have been developed…

Image and Video Processing · Electrical Eng. & Systems 2022-10-13 Hui Xie , Weiyu Xu , Xiaodong Wu

Retinal lesions play a vital role in the accurate classification of retinal abnormalities. Many researchers have proposed deep lesion-aware screening systems that analyze and grade the progression of retinopathy. However, to the best of our…

Computer Vision and Pattern Recognition · Computer Science 2020-08-17 Taimur Hassan , Muhammad Usman Akram , Naoufel Werghi

Vessel segmentation of retinal images is a key diagnostic capability in ophthalmology. This problem faces several challenges including low contrast, variable vessel size and thickness, and presence of interfering pathology such as…

Image and Video Processing · Electrical Eng. & Systems 2020-02-19 Venkateswararao Cherukuri , Vijay Kumar BG , Raja Bala , Vishal Monga

While recent advances in deep learning have significantly advanced the state of the art for vessel detection in color fundus (CF) images, the success for detecting vessels in fluorescein angiography (FA) has been stymied due to the lack of…

Computer Vision and Pattern Recognition · Computer Science 2020-05-12 Li Ding , Mohammad H. Bawany , Ajay E. Kuriyan , Rajeev S. Ramchandran , Charles C. Wykoff , Gaurav Sharma

Automatic quantification of perifoveal vessel densities in optical coherence tomography angiography (OCT-A) images face challenges such as variable intra- and inter-image signal to noise ratios, projection artefacts from outer vasculature…

Optical coherence tomography (OCT) is a commonly-used method of extracting high resolution retinal information. Moreover there is an increasing demand for the automated retinal layer segmentation which facilitates the retinal disease…

Image and Video Processing · Electrical Eng. & Systems 2020-09-30 Zeyu Fu , Yang Sun , Xiangyu Zhang , Scott Stainton , Shaun Barney , Jeffry Hogg , William Innes , Satnam Dlay

Optical Coherence Tomography (OCT) is essential for diagnosing conditions such as glaucoma, diabetic retinopathy, and age-related macular degeneration. Accurate retinal layer segmentation enables quantitative biomarkers critical for…

Image and Video Processing · Electrical Eng. & Systems 2025-09-10 S M Asiful Islam Saky , Ugyen Tshering

Optical Coherence Tomography Angiography (OCT-A) is a non-invasive imaging technique, and has been increasingly used to image the retinal vasculature at capillary level resolution. However, automated segmentation of retinal vessels in OCT-A…

Image and Video Processing · Electrical Eng. & Systems 2020-12-10 Yuhui Ma , Huaying Hao , Huazhu Fu , Jiong Zhang , Jianlong Yang , Jiang Liu , Yalin Zheng , Yitian Zhao

Purpose: This study introduces the first adaptation of RETFound for joint optic disc (OD) and optic cup (OC) segmentation. RETFound is a well-known foundation model developed for fundus camera and optical coherence tomography images, which…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Zhenyi Zhao , Muthu Rama Krishnan Mookiah , Emanuele Trucco

Purpose: Optical Coherence Tomography Angiography (OCT-A) permits visualization of the changes to the retinal circulation due to diabetic retinopathy (DR), a microvascular complication of diabetes. We demonstrate accurate segmentation of…

Image and Video Processing · Electrical Eng. & Systems 2021-01-13 Julian Lo , Morgan Heisler , Vinicius Vanzan , Sonja Karst , Ivana Zadro Matovinovic , Sven Loncaric , Eduardo V. Navajas , Mirza Faisal Beg , Marinko V. Sarunic

Deep learning-based image segmentation and detection models have largely improved the efficiency of analyzing retinal landmarks such as optic disc (OD), optic cup (OC), and fovea. However, factors including ophthalmic disease-related…

Image and Video Processing · Electrical Eng. & Systems 2023-05-22 Huaqing He , Li Lin , Zhiyuan Cai , Pujin Cheng , Xiaoying Tang
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