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We introduce a novel graph-based Retrieval-Augmented Generation (RAG) framework specifically designed for the medical domain, called \textbf{MedGraphRAG}, aimed at enhancing Large Language Model (LLM) capabilities for generating…

Computer Vision and Pattern Recognition · Computer Science 2024-10-17 Junde Wu , Jiayuan Zhu , Yunli Qi , Jingkun Chen , Min Xu , Filippo Menolascina , Vicente Grau

Large language models (LLMs) are rapidly transforming various domains, including biomedicine and healthcare, and demonstrate remarkable potential from scientific research to new drug discovery. Graph-based retrieval-augmented generation…

Quantitative Methods · Quantitative Biology 2025-11-14 Guofeng Meng , Li Shen , Qiuyan Zhong , Wei Wang , Haizhou Zhang , Xiaozhen Wang

Knowledge Graphs have been one of the fundamental methods for integrating heterogeneous data sources. Integrating heterogeneous data sources is crucial, especially in the biomedical domain, where central data-driven tasks such as drug…

Machine Learning · Computer Science 2020-12-22 Islam Akef Ebeid , Majdi Hassan , Tingyi Wanyan , Jack Roper , Abhik Seal , Ying Ding

Large language models (LLMs) are transforming the way information is retrieved with vast amounts of knowledge being summarized and presented via natural language conversations. Yet, LLMs are prone to highlight the most frequently seen…

Computation and Language · Computer Science 2024-02-20 Julien Delile , Srayanta Mukherjee , Anton Van Pamel , Leonid Zhukov

Biomedical networks (or graphs) are universal descriptors for systems of interacting elements, from molecular interactions and disease co-morbidity to healthcare systems and scientific knowledge. Advances in artificial intelligence,…

Machine Learning · Computer Science 2025-02-07 Michelle M. Li , Kexin Huang , Marinka Zitnik

The vast amount of biomedical information available today presents a significant challenge for investigators seeking to digest, process, and understand these findings effectively. Large Language Models (LLMs) have emerged as powerful tools…

Computation and Language · Computer Science 2024-07-19 Alexander R. Pelletier , Joseph Ramirez , Irsyad Adam , Simha Sankar , Yu Yan , Ding Wang , Dylan Steinecke , Wei Wang , Peipei Ping

Large language models (LLMs) have significantly advanced the field of natural language generation. However, they frequently generate unverified outputs, which compromises their reliability in critical applications. In this study, we propose…

Computation and Language · Computer Science 2025-02-18 Alexandru Lecu , Adrian Groza , Lezan Hawizy

Retrieval-Augmented Generation (RAG) systems for biomedical literature are typically evaluated using ranking metrics like Mean Reciprocal Rank (MRR), which measure how well the system identifies the single most relevant chunk. We argue that…

Artificial Intelligence · Computer Science 2026-03-25 Pouria Mortezaagha , Arya Rahgozar

Large language models (LLMs) have demonstrated remarkable capabilities in a wide range of tasks, yet their application to specialized domains remains challenging due to the need for deep expertise. Retrieval-Augmented generation (RAG) has…

Computation and Language · Computer Science 2025-09-30 Qinggang Zhang , Shengyuan Chen , Yuanchen Bei , Zheng Yuan , Huachi Zhou , Zijin Hong , Hao Chen , Yilin Xiao , Chuang Zhou , Junnan Dong , Yi Chang , Xiao Huang

Digital libraries provide different access paths, allowing users to explore their collections. For instance, paper recommendation suggests literature similar to some selected paper. Their implementation is often cost-intensive, especially…

Information Retrieval · Computer Science 2024-12-23 Hermann Kroll , Christin K. Kreutz , Bill Matthias Thang , Philipp Schaer , Wolf-Tilo Balke

Recent studies show that Generative Relevance Feedback (GRF), using text generated by Large Language Models (LLMs), can enhance the effectiveness of query expansion. However, LLMs can generate irrelevant information that harms retrieval…

Information Retrieval · Computer Science 2023-06-19 Iain Mackie , Ivan Sekulic , Shubham Chatterjee , Jeffrey Dalton , Fabio Crestani

Clinical decision-making agents can benefit from reusing prior decision experience. However, many memory-augmented methods store experiences as independent records without explicit relational structure, which may introduce noisy retrieval,…

Artificial Intelligence · Computer Science 2026-03-24 Xiao Han , Yuzheng Fan , Sendong Zhao , Haochun Wang , Bing Qin

Automated entity relation extraction (RE) from literature provides an important source for constructing biomedical database, which is more efficient and extensible than manual curation. However, existing RE models usually ignore the…

Computation and Language · Computer Science 2019-06-25 Lixiang Hong , JinJian Lin , Jiang Tao , Jianyang Zeng

Large Language Models (LLMs) are being adopted at an unprecedented rate, yet still face challenges in knowledge-intensive domains like biomedicine. Solutions such as pre-training and domain-specific fine-tuning add substantial computational…

In this study, we investigate using graph neural network (GNN) representations to enhance contextualized representations of pre-trained language models (PLMs) for keyphrase extraction from lengthy documents. We show that augmenting a PLM…

Computation and Language · Computer Science 2023-05-17 Roberto Martínez-Cruz , Debanjan Mahata , Alvaro J. López-López , José Portela

Autonomous robot exploration (ARE) is the process of a robot autonomously navigating and mapping an unknown environment. Recent Reinforcement Learning (RL)-based approaches typically formulate ARE as a sequential decision-making problem…

Robotics · Computer Science 2025-09-17 Haozhan Ni , Jingsong Liang , Chenyu He , Yuhong Cao , Guillaume Sartoretti

This paper proposes a medical literature summary generation method based on the BERT model to address the challenges brought by the current explosion of medical information. By fine-tuning and optimizing the BERT model, we develop an…

Computation and Language · Computer Science 2024-10-29 Jiacheng Hu , Yiru Cang , Guiran Liu , Meiqi Wang , Weijie He , Runyuan Bao

Document screening is a central task within Evidenced Based Medicine, which is a clinical discipline that supplements scientific proof to back medical decisions. Given the recent advances in DL (Deep Learning) methods applied to Information…

Information Retrieval · Computer Science 2021-04-20 Alexandros Ioannidis

Knowledge graphs and large language models (LLMs) are key tools for biomedical knowledge integration and reasoning, facilitating structured organization of scientific articles and discovery of complex semantic relationships. However,…

Computation and Language · Computer Science 2025-04-01 Yichun Feng , Jiawei Wang , Ruikun He , Lu Zhou , Yixue Li

Large Language Models (LLMs) have swiftly emerged as vital resources for different applications in the biomedical and healthcare domains; however, these models encounter issues such as generating inaccurate information or hallucinations.…

Computation and Language · Computer Science 2024-05-06 Mingchen Li , Halil Kilicoglu , Hua Xu , Rui Zhang
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