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Biomedical summarization requires large datasets to train for text generation. We show that while transfer learning offers a viable option for addressing this challenge, an in-domain pre-training does not always offer advantages in a BioASQ…

Computation and Language · Computer Science 2023-07-11 Dima Galat , Marian-Andrei Rizoiu

Commonsense reasoning benchmarks have been largely solved by fine-tuning language models. The downside is that fine-tuning may cause models to overfit to task-specific data and thereby forget their knowledge gained during pre-training.…

Computation and Language · Computer Science 2021-09-08 Kaixin Ma , Filip Ilievski , Jonathan Francis , Satoru Ozaki , Eric Nyberg , Alessandro Oltramari

We explore how continued pre-training on domain-specific corpora influences large language models, revealing that training on the raw corpora endows the model with domain knowledge, but drastically hurts its prompting ability for question…

Computation and Language · Computer Science 2024-07-26 Daixuan Cheng , Shaohan Huang , Furu Wei

The development of large language models leads to the formation of a pre-train-then-align paradigm, in which the model is typically pre-trained on a large text corpus and undergoes a tuning stage to align the model with human preference or…

Computation and Language · Computer Science 2025-03-19 Kaiser Sun , Mark Dredze

Deep learning techniques have revolutionised medical imaging, improving diagnostic accuracy and enabling both more accurate and earlier disease detection. However, the relationship between pre-training strategies and downstream performance…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Felix Krones

Large language models are classically trained in stages: pretraining on raw text followed by post-training for instruction following and reasoning. However, this separation creates a fundamental limitation: many desirable behaviors such as…

Pre-trained machine learning (ML) models have shown great performance for a wide range of applications, in particular in natural language processing (NLP) and computer vision (CV). Here, we study how pre-training could be used for…

Machine Learning · Computer Science 2024-01-05 Shashank Subramanian , Peter Harrington , Kurt Keutzer , Wahid Bhimji , Dmitriy Morozov , Michael Mahoney , Amir Gholami

In data-rich domains such as vision, language, and speech, deep learning prevails to deliver high-performance task-specific models and can even learn general task-agnostic representations for efficient finetuning to downstream tasks.…

Machine Learning · Computer Science 2023-12-07 Pin-Yu Chen

The recent success of question answering systems is largely attributed to pre-trained language models. However, as language models are mostly pre-trained on general domain corpora such as Wikipedia, they often have difficulty in…

Computation and Language · Computer Science 2019-09-19 Wonjin Yoon , Jinhyuk Lee , Donghyeon Kim , Minbyul Jeong , Jaewoo Kang

Pre-training is a widely used approach to develop models that are robust to distribution shifts. However, in practice, its effectiveness varies: fine-tuning a pre-trained model improves robustness significantly in some cases but not at all…

Machine Learning · Computer Science 2024-12-24 Benjamin Cohen-Wang , Joshua Vendrow , Aleksander Madry

The rate at which medical questions are asked online far exceeds the capacity of qualified people to answer them, and many of these questions are not unique. Identifying same-question pairs could enable questions to be answered more…

Machine Learning · Computer Science 2019-11-18 Clara McCreery , Namit Katariya , Anitha Kannan , Manish Chablani , Xavier Amatriain

Large language models are versatile tools but are not suitable for small inference budgets. Small models have more efficient inference, but their lower capacity means that their performance can be good only if one limits their scope to a…

Machine Learning · Computer Science 2024-11-01 David Grangier , Angelos Katharopoulos , Pierre Ablin , Awni Hannun

Pretraining DNA language models (DNALMs) on the full human genome is resource-intensive, yet often considered necessary for strong downstream performance. Inspired by recent findings in NLP and long-context modeling, we explore an…

Genomics · Quantitative Biology 2025-06-24 Sohan Mupparapu , Parameswari Krishnamurthy , Ratish Puduppully

In the last decade, the generalization and adaptation abilities of deep learning models were typically evaluated on fixed training and test distributions. Contrary to traditional deep learning, large language models (LLMs) are (i) even more…

Computation and Language · Computer Science 2024-10-17 Fırat Öncel , Matthias Bethge , Beyza Ermis , Mirco Ravanelli , Cem Subakan , Çağatay Yıldız

Recent approaches to Open-domain Question Answering refer to an external knowledge base using a retriever model, optionally rerank passages with a separate reranker model and generate an answer using another reader model. Despite performing…

Computation and Language · Computer Science 2022-10-31 Haejun Lee , Akhil Kedia , Jongwon Lee , Ashwin Paranjape , Christopher D. Manning , Kyoung-Gu Woo

Biomedical Question Answering aims to obtain an answer to the given question from the biomedical domain. Due to its high requirement of biomedical domain knowledge, it is difficult for the model to learn domain knowledge from limited…

Computation and Language · Computer Science 2022-06-29 Yuxuan Lu , Jingya Yan , Zhixuan Qi , Zhongzheng Ge , Yongping Du

Medical image visual question answering (VQA) is a task to answer clinical questions, given a radiographic image, which is a challenging problem that requires a model to integrate both vision and language information. To solve medical VQA…

Computer Vision and Pattern Recognition · Computer Science 2022-11-28 Pengfei Li , Gang Liu , Lin Tan , Jinying Liao , Shenjun Zhong

There is growing interest in the automated extraction of relevant information from clinical dialogues. However, it is difficult to collect and construct large annotated resources for clinical dialogue tasks. Recent developments in natural…

Computation and Language · Computer Science 2022-06-07 Zhengyuan Liu , Pavitra Krishnaswamy , Nancy F. Chen

With the growing amount of text in health data, there have been rapid advances in large pre-trained models that can be applied to a wide variety of biomedical tasks with minimal task-specific modifications. Emphasizing the cost of these…

Language models pretrained on text from a wide variety of sources form the foundation of today's NLP. In light of the success of these broad-coverage models, we investigate whether it is still helpful to tailor a pretrained model to the…

Computation and Language · Computer Science 2020-05-07 Suchin Gururangan , Ana Marasović , Swabha Swayamdipta , Kyle Lo , Iz Beltagy , Doug Downey , Noah A. Smith
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