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We propose the Graph Context Encoder (GCE), a simple but efficient approach for graph representation learning based on graph feature masking and reconstruction. GCE models are trained to efficiently reconstruct input graphs similarly to a…

Machine Learning · Computer Science 2021-06-21 Oriel Frigo , Rémy Brossard , David Dehaene

The growth in the use of computationally intensive statistical procedures, especially with Big Data, has necessitated the usage of parallel computation on diverse platforms such as multicore, GPU, clusters and clouds. However, slowdown due…

Computation · Statistics 2014-09-23 Norman Matloff

It is common practice for chemists to search chemical databases based on substructures of compounds for finding molecules with desired properties. The purpose of de novo molecular generation is to generate instead of search. Existing…

Chemical Physics · Physics 2021-02-10 Ryuichiro Hataya , Hideki Nakayama , Kazuki Yoshizoe

Graph signals are widely used to describe vertex attributes or features in graph-structured data, with applications spanning the internet, social media, transportation, sensor networks, and biomedicine. Graph signal processing (GSP) has…

Signal Processing · Electrical Eng. & Systems 2025-05-22 Yu Zhang , Linyu Peng , Bing-Zhao Li

Energy-Based Models (EBMs) have proven to be a highly effective approach for modelling densities on finite-dimensional spaces. Their ability to incorporate domain-specific choices and constraints into the structure of the model through…

Machine Learning · Computer Science 2023-02-24 Jen Ning Lim , Sebastian Vollmer , Lorenz Wolf , Andrew Duncan

Graph computational tasks are inherently challenging and often demand the development of advanced algorithms for effective solutions. With the emergence of large language models (LLMs), researchers have begun investigating their potential…

Computation and Language · Computer Science 2025-01-24 Chang Gong , Wanrui Bian , Zhijie Zhang , Weiguo Zheng

Nowadays, data-intensive applications are gaining popularity and, together with this trend, processing-in-memory (PIM)-based systems are being given more attention and have become more relevant. This paper describes an analytical modeling…

Hardware Architecture · Computer Science 2021-07-23 Ronny Ronen , Adi Eliahu , Orian Leitersdorf , Natan Peled , Kunal Korgaonkar , Anupam Chattopadhyay , Ben Perach , Shahar Kvatinsky

In silico tools are important for generating novel hypotheses and exploring alternatives in de novo metabolic pathway design. However, while many computational frameworks have been proposed for retrobiosynthesis, few successful examples of…

Machine Learning · Computer Science 2026-04-16 Peter Zhiping Zhang , Jeffrey D. Varner

It is shown in "SIAM J. Sci. Comput. 39 (2017):B424-B441" that free-form curves used in computer aided geometric design can usually be represented as the solutions of linear differential systems and points and derivatives on the curves can…

Numerical Analysis · Computer Science 2019-11-05 Xunnian Yang , Jialin Hong

Applied process calculi include advanced programming constructs such as type systems, communication with pattern matching, encryption primitives, concurrent constraints, nondeterminism, process creation, and dynamic connection topologies.…

Logic in Computer Science · Computer Science 2017-01-11 Johannes Borgström , Ramūnas Gutkovas , Joachim Parrow , Björn Victor , Johannes Åman Pohjola

Our work introduces an innovative approach to graph learning by leveraging Hyperdimensional Computing. Graphs serve as a widely embraced method for conveying information, and their utilization in learning has gained significant attention.…

Machine Learning · Computer Science 2024-03-20 Pere Verges , Igor Nunes , Mike Heddes , Tony Givargis , Alexandru Nicolau

Peptides offer great biomedical potential and serve as promising drug candidates. Currently, the majority of approved peptide drugs are directly derived from well-explored natural human peptides. It is quite necessary to utilize advanced…

Biomolecules · Quantitative Biology 2024-01-29 Yipin Lei , Xu Wang , Meng Fang , Han Li , Xiang Li , Jianyang Zeng

Graph coloring is often used in parallelizing scientific computations that run in distributed and multi-GPU environments; it identifies sets of independent data that can be updated in parallel. Many algorithms exist for graph coloring on a…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-07-02 Ian Bogle , Erik G Boman , Karen D Devine , Sivasankaran Rajamanickam , George M Slota

In this report, we present a new programming model based on Pipelines and Operators, which are the building blocks of programs written in PiCo, a DSL for Data Analytics Pipelines. In the model we propose, we use the term Pipeline to denote…

Programming Languages · Computer Science 2017-05-05 Maurizio Drocco , Claudia Misale , Guy Tremblay , Marco Aldinucci

We present here a set of examples, classes and tools which can be used for statistical analysis in Graphics Processing Units (GPU). This includes binned and unbinned maximum likelihood fits, pseudo-experiment generation, convolutions,…

Recent research has made significant progress in optimizing diffusion models for downstream objectives, which is an important pursuit in fields such as graph generation for drug design. However, directly applying these models to graph…

Machine Learning · Computer Science 2024-10-28 Yijing Liu , Chao Du , Tianyu Pang , Chongxuan Li , Min Lin , Wei Chen

Generative deep learning has become pivotal in molecular design for drug discovery, materials science, and chemical engineering. A widely used paradigm is to pretrain neural networks on string representations of molecules and fine-tune them…

Machine Learning · Computer Science 2025-03-21 Jonathan Pirnay , Jan G. Rittig , Alexander B. Wolf , Martin Grohe , Jakob Burger , Alexander Mitsos , Dominik G. Grimm

Graph embedding aims at learning a vector-based representation of vertices that incorporates the structure of the graph. This representation then enables inference of graph properties. Existing graph embedding techniques, however, do not…

Graph embedding techniques have been increasingly deployed in a multitude of different applications that involve learning on non-Euclidean data. However, existing graph embedding models either fail to incorporate node attribute information…

Machine Learning · Computer Science 2021-06-22 Chenhui Deng , Zhiqiang Zhao , Yongyu Wang , Zhiru Zhang , Zhuo Feng

Systematic discovery of optimization paths in quantum circuit simplification remains a challenge. Today, ZX-calculus, a computing model for quantum circuit transformation, is attracting attention for its highly abstract graph-based…

Programming Languages · Computer Science 2025-11-20 Kayo Tei , Haruto Mishina , Naoki Yamamoto , Kazunori Ueda