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We investigate the impact of choosing regressors and molecular representations for the construction of fast machine learning (ML) models of thirteen electronic ground-state properties of organic molecules. The performance of each…

This study investigates explainable machine learning algorithms for identifying depression from speech. Grounded in evidence from speech production that depression affects motor control and vowel generation, pre-trained vowel-based…

Machine Learning · Computer Science 2024-10-25 Kexin Feng , Theodora Chaspari

Recently, template-based (TB) and template-free (TF) molecule graph learning methods have shown promising results to retrosynthesis. TB methods are more accurate using pre-encoded reaction templates, and TF methods are more scalable by…

Machine Learning · Computer Science 2022-02-17 Zhangyang Gao , Cheng Tan , Lirong Wu , Stan Z. Li

Use of large language models such as ChatGPT (GPT-4/GPT-5) for mental health support has grown rapidly, emerging as a promising route to assess and help people with mood disorders like depression. However, we have a limited understanding of…

Design of new drugs is a challenging process: a candidate molecule should satisfy multiple conditions to act properly and make the least side-effect -- perfect candidates selectively attach to and influence only targets, leaving off-targets…

Biomolecules · Quantitative Biology 2024-05-07 Andrij Rovenchak , Maksym Druchok

In today's fast-paced world, the rates of stress and depression present a surge. Social media provide assistance for the early detection of mental health conditions. Existing methods mainly introduce feature extraction approaches and train…

Computation and Language · Computer Science 2023-07-07 Loukas Ilias , Spiros Mouzakitis , Dimitris Askounis

Machine learning and deep learning have gained popularity and achieved immense success in Drug discovery in recent decades. Historically, machine learning and deep learning models were trained on either structural data or chemical…

Machine Learning · Statistics 2019-09-18 Huy Ngoc Pham , Trung Hoang Le

This study explores the application potential of a deep learning model based on the CNN-LSTM framework in forecasting the sales volume of cancer drugs, with a focus on modeling complex time series data. As advancements in medical technology…

Computational Engineering, Finance, and Science · Computer Science 2025-06-30 Yinghan Li , Yilin Yao , Junghua Lin , Nanxi Wang

Machine learning (ML) has revolutionized medical prognostics by integrating advanced algorithms with clinical data to enhance disease prediction, risk assessment, and patient outcome forecasting. This comprehensive review critically…

Machine Learning · Computer Science 2024-08-06 Michael Fascia

Survival prognosis is crucial for medical informatics. Practitioners often confront small-sized clinical data, especially cancer patient cases, which can be insufficient to induce useful patterns for survival predictions. This study deals…

Machine Learning · Computer Science 2025-01-23 Yonghao Zhao , Changtao Li , Chi Shu , Qingbin Wu , Hong Li , Chuan Xu , Tianrui Li , Ziqiang Wang , Zhipeng Luo , Yazhou He

The design of high-entropy alloys (HEA) with desired properties is challenging due to their large compositional space. While various machine learning (ML) models can predict specific HEA solid-solution phases (SS), predicting high-entropy…

Materials Science · Physics 2023-06-27 Jie Qi , Diego Ibarra Hoyos , S. Joseph Poon

Peptide receptor radionuclide therapy (PRRT) is an established treatment for metastatic neuroendocrine tumors (NETs), yet long-term disease control occurs only in a subset of patients. Predicting progression-free survival (PFS) could…

In silico prediction of cardiotoxicity with high sensitivity and specificity for potential drug molecules can be of immense value. Hence, building machine learning classification models, based on some features extracted from the molecular…

Quantitative Methods · Quantitative Biology 2021-06-09 Aditya Sarkar , Arnav Bhavsar

Nowadays, speech emotion recognition (SER) plays a vital role in the field of human-computer interaction (HCI) and the evolution of artificial intelligence (AI). Our proposed DCRF-BiLSTM model is used to recognize seven emotions: neutral,…

Sound · Computer Science 2026-01-15 Shahana Yasmin Chowdhury , Bithi Banik , Md Tamjidul Hoque , Shreya Banerjee

Objective: EEG-based methods can predict speech intelligibility, but their accuracy and robustness lag behind behavioral tests, which typically show test-retest differences under 1 dB. We introduce the multi-decoder method to predict speech…

Signal Processing · Electrical Eng. & Systems 2026-02-04 Rien Sonck , Bernd Accou , Tom Francart , Jonas Vanthornhout

3\b{eta}-O-phthalic ester of betulinic acid is of great importance in anticancer studies. However, the optimization of its reaction conditions requires a large number of experimental works. To simplify the number of times of optimization in…

Machine Learning · Computer Science 2015-11-13 Run Wang , Qiaoli Mo , Qian Zhang , Fudi Chen , Dazuo Yang

This work proposes an attention-based sequence-to-sequence model for handwritten word recognition and explores transfer learning for data-efficient training of HTR systems. To overcome training data scarcity, this work leverages models…

Computer Vision and Pattern Recognition · Computer Science 2022-09-13 Dmitrijs Kass , Ekta Vats

Explainable ML for molecular toxicity prediction is a promising approach for efficient drug development and chemical safety. A predictive ML model of toxicity can reduce experimental cost and time while mitigating ethical concerns by…

Quantitative Methods · Quantitative Biology 2022-04-15 Bhanushee Sharma , Vijil Chenthamarakshan , Amit Dhurandhar , Shiranee Pereira , James A. Hendler , Jonathan S. Dordick , Payel Das

Disease classification is a crucial element of biomedical research. Recent studies have demonstrated that machine learning techniques, such as Support Vector Machine (SVM) modeling, produce similar or improved predictive capabilities in…

Machine Learning · Statistics 2017-08-02 Jessica M. Rudd

Heart disease is a serious global health issue that claims millions of lives every year. Early detection and precise prediction are critical to the prevention and successful treatment of heart related issues. A lot of research utilizes…

Machine Learning · Computer Science 2024-07-30 Rahul Karmakar , Udita Ghosh , Arpita Pal , Sattwiki Dey , Debraj Malik , Priyabrata Sain