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Natural language processing (NLP) of clinical trial documents can be useful in new trial design. Here we identify entity types relevant to clinical trial design and propose a framework called CT-BERT for information extraction from clinical…

Quantitative Methods · Quantitative Biology 2021-10-20 Xiong Liu , Greg L. Hersch , Iya Khalil , Murthy Devarakonda

Crucial information about the practice of healthcare is recorded only in free-form text, which creates an enormous opportunity for high-impact NLP. However, annotated healthcare datasets tend to be small and expensive to obtain, which…

Computation and Language · Computer Science 2019-04-09 Yifeng Tao , Bruno Godefroy , Guillaume Genthial , Christopher Potts

Several biomedical language models have already been developed for clinical language inference. However, these models typically utilize general vocabularies and are trained on relatively small clinical corpora. We sought to evaluate the…

Computation and Language · Computer Science 2022-10-14 Madhumita Sushil , Dana Ludwig , Atul J. Butte , Vivek A. Rudrapatna

Medication errors most commonly occur at the ordering or prescribing stage, potentially leading to medical complications and poor health outcomes. While it is possible to catch these errors using different techniques; the focus of this work…

Computation and Language · Computer Science 2022-01-11 Yu Jiang , Christian Poellabauer

The rapidly increasing volume of electronic health record (EHR) data underscores a pressing need to unlock biomedical knowledge from unstructured clinical texts to support advancements in data-driven clinical systems, including patient…

Computation and Language · Computer Science 2025-10-21 Manuela Daniela Danu , George Marica , Constantin Suciu , Lucian Mihai Itu , Oladimeji Farri

The objective of this study is to develop natural language processing (NLP) models that can analyze patients' drug reviews and accurately classify their satisfaction levels as positive, neutral, or negative. Such models would reduce the…

Computation and Language · Computer Science 2023-08-09 Yue Ling

A considerable number of texts encountered daily are somehow connected with each other. For example, Wikipedia articles refer to other articles via hyperlinks, scientific papers relate to others via citations or (co)authors, while tweets…

Computation and Language · Computer Science 2025-08-08 Albert Roethel , Maria Ganzha , Anna Wróblewska

Large pre-trained language models (LMs) have been widely adopted in biomedical and clinical domains, introducing many powerful LMs such as bio-lm and BioELECTRA. However, the applicability of these methods to real clinical use cases is…

Computation and Language · Computer Science 2022-11-16 Samuel Cahyawijaya , Bryan Wilie , Holy Lovenia , Huan Zhong , MingQian Zhong , Yuk-Yu Nancy Ip , Pascale Fung

Large language models (LLMs) such as GPT-4o and o1 have demonstrated strong performance on clinical natural language processing (NLP) tasks across multiple medical benchmarks. Nonetheless, two high-impact NLP tasks - structured tabular…

Clinical notes in Electronic Health Records (EHR) present rich documented information of patients to inference phenotype for disease diagnosis and study patient characteristics for cohort selection. Unsupervised user embedding aims to…

Computation and Language · Computer Science 2022-03-30 Xiaolei Huang , Franck Dernoncourt , Mark Dredze

Recently, pretrained language models based on BERT have been introduced for the French biomedical domain. Although these models have achieved state-of-the-art results on biomedical and clinical NLP tasks, they are constrained by a limited…

Computation and Language · Computer Science 2024-02-27 Adrien Bazoge , Emmanuel Morin , Beatrice Daille , Pierre-Antoine Gourraud

We introduce NoteChat, a novel cooperative multi-agent framework leveraging Large Language Models (LLMs) to generate patient-physician dialogues. NoteChat embodies the principle that an ensemble of role-specific LLMs, through structured…

Computation and Language · Computer Science 2025-01-30 Junda Wang , Zonghai Yao , Zhichao Yang , Huixue Zhou , Rumeng Li , Xun Wang , Yucheng Xu , Hong Yu

The recent adoption of Electronic Health Records (EHRs) by health care providers has introduced an important source of data that provides detailed and highly specific insights into patient phenotypes over large cohorts. These datasets, in…

A growing body of work uses Natural Language Processing (NLP) methods to automatically generate medical notes from audio recordings of doctor-patient consultations. However, there are very few studies on how such systems could be used in…

Deep learning (DL) based predictive models from electronic health records (EHR) deliver impressive performance in many clinical tasks. Large training cohorts, however, are often required to achieve high accuracy, hindering the adoption of…

Computation and Language · Computer Science 2020-05-27 Laila Rasmy , Yang Xiang , Ziqian Xie , Cui Tao , Degui Zhi

This paper describes novel models tailored for a new application, that of extracting the symptoms mentioned in clinical conversations along with their status. Lack of any publicly available corpus in this privacy-sensitive domain led us to…

Computation and Language · Computer Science 2019-06-07 Nan Du , Kai Chen , Anjuli Kannan , Linh Tran , Yuhui Chen , Izhak Shafran

Biomedical text mining is becoming increasingly important as the number of biomedical documents and web data rapidly grows. Recently, word representation models such as BERT has gained popularity among researchers. However, it is difficult…

Computation and Language · Computer Science 2023-01-26 Ningyu Zhang , Qianghuai Jia , Kangping Yin , Liang Dong , Feng Gao , Nengwei Hua

Recent advances in natural language processing (NLP) can be largely attributed to the advent of pre-trained language models such as BERT and RoBERTa. While these models demonstrate remarkable performance on general datasets, they can…

Objective: Text mining of clinical notes embedded in electronic medical records is increasingly used to extract patient characteristics otherwise not or only partly available, to assess their association with relevant health outcomes. As…

Computation and Language · Computer Science 2023-01-18 Madhumita Sushil , Atul J. Butte , Ewoud Schuit , Maarten van Smeden , Artuur M. Leeuwenberg

Electronic phenotyping is the task of ascertaining whether an individual has a medical condition of interest by analyzing their medical record and is foundational in clinical informatics. Increasingly, electronic phenotyping is performed…

Machine Learning · Statistics 2019-01-08 Daisy Yi Ding , Chloé Simpson , Stephen Pfohl , Dave C. Kale , Kenneth Jung , Nigam H. Shah
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