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The paper presents a novel, principled approach to train recurrent neural networks from the Reservoir Computing family that are robust to missing part of the input features at prediction time. By building on the ensembling properties of…

Machine Learning · Computer Science 2017-05-09 Davide Bacciu , Francesco Crecchi , Davide Morelli

Hydrofluoroolefins are considered the most promising next-generation refrigerants due to their extremely low global warming potential values, which can effectively mitigate the global warming effect. However, the lack of reliable…

Machine Learning · Computer Science 2025-07-30 Gang Wang , Peng Hu

Media compression standards have reached a plateau in terms of the rate-distortion-complexity trade-off, limiting the ability to offload expensive AI perception to the cloud in applications like robotics, wearables, and remote sensing.…

Image and Video Processing · Electrical Eng. & Systems 2026-05-29 Dan Jacobellis , Neeraja J. Yadwadkar

A statistical model of protein families, called profile conditional random fields (CRFs), is proposed. This model may be regarded as an integration of the profile hidden Markov model (HMM) and the Finkelstein-Reva (FR) theory of protein…

Biomolecules · Quantitative Biology 2009-06-01 Akira R. Kinjo

We consider error-correcting coding for deoxyribonucleic acid (DNA)-based storage using nanopore sequencing. We model the DNA storage channel as a sampling noise channel where the input data is chunked into $M$ short DNA strands, which are…

Information Theory · Computer Science 2024-06-21 Lorenz Welter , Roman Sokolovskii , Thomas Heinis , Antonia Wachter-Zeh , Eirik Rosnes , Alexandre Graell i Amat

The method of "random Fourier features (RFF)" has become a popular tool for approximating the "radial basis function (RBF)" kernel. The variance of RFF is actually large. Interestingly, the variance can be substantially reduced by a simple…

Machine Learning · Computer Science 2017-02-22 Ping Li

In this work, we study an integrated fault detection and classification framework called FARM for fast, accurate, and robust online chemical process monitoring. The FARM framework integrates the latest advancements in statistical process…

Signal Processing · Electrical Eng. & Systems 2025-10-31 Alireza Miraliakbar , Fangyuan Ma , Zheyu Jiang

Computational RNA secondary structure prediction is rather well established. However, such prediction algorithms always depend on a large number of experimentally measured parameters. Here, we study how sensitive structure prediction…

Quantitative Methods · Quantitative Biology 2007-05-23 D. M. Layton , R. Bundschuh

Accurate prediction of liquid viscosity is essential for process design and simulation, yet remains challenging for novel molecules. Conventional group-contribution models struggle with isomer discrimination, large molecules, and parameter…

Electrospinning is a versatile nanofabrication technique whose outcomes emerge from a complex, high-dimensional interplay between solution properties, processing parameters, and environmental conditions. Optimizing this parameter space for…

Databases · Computer Science 2026-05-13 Mehrab Mahdian , Ferenc Ender , Tamas Pardy

The ubiquitous time-delay estimation (TDE) problem becomes nontrivial when sensors are non-co-located and communication between them is limited. Building on the recently proposed "extremum encoding" compression-estimation scheme, we address…

Signal Processing · Electrical Eng. & Systems 2024-12-25 Amir Weiss , Yuval Kochman , Gregory W. Wornell

RNA co-transcriptionality, where RNA is spliced or folded during transcription from DNA templates, offers promising potential for molecular programming. It enables programmable folding of nano-scale RNA structures and has recently been…

Formal Languages and Automata Theory · Computer Science 2025-07-01 Da-Jung Cho , Szilárd Zsolt Fazekas , Shinnosuke Seki , Max Wiedenhöft

Purpose: This study aimed to enhance protein sequence classification using natural language processing (NLP) techniques while addressing the impact of sequence similarity on model performance. We compared various machine learning and deep…

Quantitative Methods · Quantitative Biology 2025-05-26 Huma Perveen , Julie Weeds

Bayesian inference methods rely on numerical algorithms for both model selection and parameter inference. In general, these algorithms require a high computational effort to yield reliable estimates. One of the major challenges in…

Quantitative Methods · Quantitative Biology 2018-08-09 Patricio Maturana , Brendon J. Brewer , Steffen Klaere , Remco Bouckaert

Recurrent neural networks (RNNs) are a widely used tool for modeling sequential data, yet they are often treated as inscrutable black boxes. Given a trained recurrent network, we would like to reverse engineer it--to obtain a quantitative,…

Machine Learning · Computer Science 2019-12-06 Niru Maheswaranathan , Alex Williams , Matthew D. Golub , Surya Ganguli , David Sussillo

This paper revisits the Neonatal Convolutional Neural Network (N-CNN) by optimizing its hyperparameters and evaluating how they affect its classification metrics, explainability and reliability, discussing their potential impact in clinical…

Foundation models for single-cell RNA sequencing (scRNA-seq) have shown promising capabilities in capturing gene expression patterns. However, current approaches face critical limitations: they ignore biological prior knowledge encoded in…

Machine Learning · Computer Science 2025-03-04 Mufan Qiu , Xinyu Hu , Fengwei Zhan , Sukwon Yun , Jie Peng , Ruichen Zhang , Bhavya Kailkhura , Jiekun Yang , Tianlong Chen

With the development of large language models, fine-tuning has emerged as an effective method to enhance performance in specific scenarios by injecting domain-specific knowledge. In this context, model merging techniques provide a solution…

Computation and Language · Computer Science 2025-09-18 Zijian Li , Xiaocheng Feng , Huixin Liu , Yichong Huang , Ting Liu , Bing Qin

Feedforward neural networks (FNNs) can be viewed as non-linear regression models, where covariates enter the model through a combination of weighted summations and non-linear functions. Although these models have some similarities to the…

Methodology · Statistics 2024-05-02 Andrew McInerney , Kevin Burke

Sequence labeling is a widely used method for named entity recognition and information extraction from unstructured natural language data. In clinical domain one major application of sequence labeling involves extraction of medical entities…

Computation and Language · Computer Science 2016-08-03 Abhyuday Jagannatha , Hong Yu