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With the accelerating availability of multimodal surgical data and real-time computation, Surgical Digital Twins (SDTs) have emerged as virtual counterparts that mirror, predict, and inform decisions across pre-, intra-, and postoperative…

In explainable artificial intelligence (XAI) research, the predominant focus has been on interpreting models for experts and practitioners. Model agnostic and local explanation approaches are deemed interpretable and sufficient in many…

Artificial Intelligence · Computer Science 2024-02-01 Adarsa Sivaprasad , Ehud Reiter , Nava Tintarev , Nir Oren

This paper discusses and explores the potential and relevance of recent developments in artificial intelligence (AI) and digital twins for health and well-being in low-resource African countries. We use the case of public health emergency…

Artificial Intelligence · Computer Science 2023-07-11 Deshendran Moodley , Christopher Seebregts

Clinical decision support systems (CDSS) augmented with artificial intelligence (AI) models are emerging as potentially valuable tools in healthcare. Despite their promise, the development and implementation of these systems typically…

Human-Computer Interaction · Computer Science 2023-03-08 Grace Golden , Christina Popescu , Sonia Israel , Kelly Perlman , Caitrin Armstrong , Robert Fratila , Myriam Tanguay-Sela , David Benrimoh

Major depressive disorder is a debilitating disease affecting 264 million people worldwide. While many antidepressant medications are available, few clinical guidelines support choosing among them. Decision support tools (DSTs) embodying…

Digital Twin (DT) technology has emerged as a transformative approach in healthcare, but its application in personalized patient care remains limited. This paper aims to present a practical implementation of DT in the management of chronic…

Quantitative Methods · Quantitative Biology 2025-07-17 Javad M Alizadeh , Mukesh K Patel , Huanmei Wu

Artificial intelligence and medicine have a longstanding and proficuous relationship. In the present work we develop a brief assessment of this relationship with specific focus on machine learning, in which we highlight some critical points…

Artificial Intelligence · Computer Science 2018-11-13 Flavio S Correa da Silva , Frederico P Costa , Antonio F Iemma

Actionable Cognitive Twins are the next generation Digital Twins enhanced with cognitive capabilities through a knowledge graph and artificial intelligence models that provide insights and decision-making options to the users. The knowledge…

Artificial Intelligence · Computer Science 2021-03-25 Jože M. Rožanec , Jinzhi Lu , Jan Rupnik , Maja Škrjanc , Dunja Mladenić , Blaž Fortuna , Xiaochen Zheng , Dimitris Kiritsis

With the increasing adoption of Artificial Intelligence (AI) systems in high-stake domains, such as healthcare, effective collaboration between domain experts and AI is imperative. To facilitate effective collaboration between domain…

Human-Computer Interaction · Computer Science 2024-05-24 Aditya Bhattacharya , Simone Stumpf , Katrien Verbert

Digital Twins technology is revolutionizing decision-making in scientific research by integrating models and simulations with real-time data. Unlike traditional Structural Health Monitoring methods, which rely on computationally intensive…

Computer Vision and Pattern Recognition · Computer Science 2024-10-10 Mehrdad Shafiei Dizaji

Digitalisation is one of the main drivers of most economic sectors nowadays and the digital twin, as a reification of digitalisation for complex systems has attracted much attention from both academics and industry. There have been studies…

Systems and Control · Electrical Eng. & Systems 2024-10-04 Guanyu Xiong , Yan Gao , Haijiang Li

Artificial intelligence-augmented technology represents a considerable opportunity for improving healthcare delivery. Significant progress has been made to demonstrate the value of complex models to enhance clinicians` efficiency in…

Human-Computer Interaction · Computer Science 2025-04-08 Mohammad Golam Kibria , Lauren Kucirka , Javed Mostafa

We develop a methodology to create data-driven predictive digital twins for optimal risk-aware clinical decision-making. We illustrate the methodology as an enabler for an anticipatory personalized treatment that accounts for uncertainties…

Computational Engineering, Finance, and Science · Computer Science 2024-06-18 Anirban Chaudhuri , Graham Pash , David A. Hormuth , Guillermo Lorenzo , Michael Kapteyn , Chengyue Wu , Ernesto A. B. F. Lima , Thomas E. Yankeelov , Karen Willcox

The growing adoption of artificial intelligence in healthcare has raised concerns about the transparency and trustworthiness of AI-driven medical diagnosis systems. Many existing models operate as black boxes, limiting clinicians' ability…

Human-Computer Interaction · Computer Science 2026-04-21 Altynbek Seitenov , Ainur Nurzhanova , Azhar Bekbussinova , Yerassyl Bolatkan

Digital Twins (DTs) are increasingly deployed across application domains, yet the treatment of trust-related issues remains unevenly addressed. To examine whether and how trust is discussed in the current landscape, we conducted a…

Computers and Society · Computer Science 2026-05-12 Chi Fai David Lam , Aad van Moorsel , Zoya Pourmirza

With the advances of IoT developments, copious sensor data are communicated through wireless networks and create the opportunity of building Digital Twins to mirror and simulate the complex physical world. Digital Twin has long been…

Machine Learning · Computer Science 2023-04-21 Jiadi Du , Tie Luo

Artificial Intelligence is rapidly advancing and radically impacting everyday life, driven by the increasing availability of computing power. Despite this trend, the adoption of AI in real-world healthcare is still limited. One of the main…

Artificial Intelligence · Computer Science 2024-12-02 Akshat Dubey , Zewen Yang , Georges Hattab

Clinical Decision Support Systems (CDSSs) provide reasoning and inquiry guidance for physicians, yet they face notable challenges, including high maintenance costs and low generalization capability. Recently, Large Language Models (LLMs)…

Computation and Language · Computer Science 2026-04-24 Yue Guo , Fanfu Wang , Jianwei Lv , Xincheng Shi , Yuchen Li , Youya Wang , Yunsheng Zeng , Yujing Liu , Yunhao Qiao , Gen Li , Junfeng Wang , Bo Yuan

Conversational diagnosis requires multi-turn history-taking, where an agent asks clarifying questions to refine differential diagnoses under incomplete information. Existing approaches often rely on the parametric knowledge of a model or…

Artificial Intelligence · Computer Science 2026-02-04 Jeongmoon Won , Seungwon Kook , Yohan Jo

From birth to death, we all experience surprisingly ubiquitous changes over time due to aging. If we can predict aging in the digital domain, that is, the digital twin of the human body, we would be able to detect lesions in their very…

Image and Video Processing · Electrical Eng. & Systems 2022-08-24 Hisaichi Shibata , Shouhei Hanaoka , Yukihiro Nomura , Naoto Hayashi , Osamu Abe
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