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Current histopathological grading of prostate cancer relies primarily on glandular architecture, largely overlooking the tumor microenvironment. Here, we present PROTAS, a deep learning framework that quantifies reactive stroma (RS) in…

Prostate cancer is the most prevalent cancer among men in Western countries, with 1.1 million new diagnoses every year. The gold standard for the diagnosis of prostate cancer is a pathologists' evaluation of prostate tissue. To potentially…

Image and Video Processing · Electrical Eng. & Systems 2020-10-23 Hans Pinckaers , Wouter Bulten , Jeroen van der Laak , Geert Litjens

Many skin lesion analysis (SLA) methods recently focused on developing a multi-modal-based multi-label classification method due to two factors. The first is multi-modal data, i.e., clinical and dermoscopy images, which can provide…

Computer Vision and Pattern Recognition · Computer Science 2023-07-06 Peng Tang , Yang Nan , Tobias Lasser

Cancer survival prediction is an active area of research that can help prevent unnecessary therapies and improve patient's quality of life. Gene expression profiling is being widely used in cancer studies to discover informative biomarkers…

Machine Learning · Computer Science 2016-11-18 Hamid Reza Hassanzadeh , John H. Phan , May D. Wang

The interpretation of prostate MRI suffers from low agreement across radiologists due to the subtle differences between cancer and normal tissue. Image registration addresses this issue by accurately mapping the ground-truth cancer labels…

To read the final version please go to IEEE TGRS on IEEE Xplore. Convolutional neural networks (CNNs) have been attracting increasing attention in hyperspectral (HS) image classification, owing to their ability to capture spatial-spectral…

Computer Vision and Pattern Recognition · Computer Science 2021-07-07 Danfeng Hong , Lianru Gao , Jing Yao , Bing Zhang , Antonio Plaza , Jocelyn Chanussot

Graph Neural Networks (GNNs) have achieved impressive performance in collaborative filtering. However, GNNs tend to yield inferior performance when the distributions of training and test data are not aligned well. Also, training GNNs…

Machine Learning · Computer Science 2023-07-19 Huiyuan Chen , Chin-Chia Michael Yeh , Yujie Fan , Yan Zheng , Junpeng Wang , Vivian Lai , Mahashweta Das , Hao Yang

Deep learning is a powerful tool for whole slide image (WSI) analysis. Typically, when performing supervised deep learning, a WSI is divided into small patches, trained and the outcomes are aggregated to estimate disease grade. However,…

Computer Vision and Pattern Recognition · Computer Science 2022-05-20 Yi Zheng , Rushin H. Gindra , Emily J. Green , Eric J. Burks , Margrit Betke , Jennifer E. Beane , Vijaya B. Kolachalama

The current study detects different morphologies related to prostate pathology using deep learning models; these models were evaluated on 2,121 hematoxylin and eosin (H&E) stain histology images captured using bright field microscopy, which…

A significant challenge in solid tumors is reliably distinguishing confounding pathologies from malignant neoplasms on routine imaging. While radiomics methods seek surrogate markers of lesion heterogeneity on CT/MRI, many aggregate…

Graph convolutional networks (GCNs) have recently achieved great empirical success in learning graph-structured data. To address its scalability issue due to the recursive embedding of neighboring features, graph topology sampling has been…

Machine Learning · Computer Science 2023-12-12 Hongkang Li , Meng Wang , Sijia Liu , Pin-Yu Chen , Jinjun Xiong

Prostate cancer is one of the most prevalent cancers worldwide. One of the key factors in reducing its mortality is based on early detection. The computer-aided diagnosis systems for this task are based on the glandular structural analysis…

Image and Video Processing · Electrical Eng. & Systems 2021-05-25 Julio Silva-Rodríguez , Elena Payá-Bosch , Gabriel García , Adrián Colomer , Valery Naranjo

The rapid progress in image classification has been largely driven by the adoption of Graph Convolutional Networks (GCNs), which offer a robust framework for handling complex data structures. This study introduces a novel approach that…

Computer Vision and Pattern Recognition · Computer Science 2025-08-22 Mustafa Mohammadi Gharasuie , Luis Rueda

Graphs are widely used to model the relational structure of data, and the research of graph machine learning (ML) has a wide spectrum of applications ranging from drug design in molecular graphs to friendship recommendation in social…

Machine Learning · Computer Science 2022-08-23 Kaize Ding , Jianling Wang , Jundong Li , James Caverlee , Huan Liu

Graph Convolutional Networks (GCNs) have shown significant improvements in semi-supervised learning on graph-structured data. Concurrently, unsupervised learning of graph embeddings has benefited from the information contained in random…

Machine Learning · Computer Science 2018-02-27 Sami Abu-El-Haija , Amol Kapoor , Bryan Perozzi , Joonseok Lee

Graphical models are commonly used to discover associations within gene or protein networks for complex diseases such as cancer. Most existing methods estimate a single graph for a population, while in many cases, researchers are interested…

Readability or difficulty estimation of words and documents has been investigated independently in the literature, often assuming the existence of extensive annotated resources for the other. Motivated by our analysis showing that there is…

Computation and Language · Computer Science 2021-04-28 Yoshinari Fujinuma , Masato Hagiwara

Graph Convolutional Networks (GCNs) have become a crucial tool on learning representations of graph vertices. The main challenge of adapting GCNs on large-scale graphs is the scalability issue that it incurs heavy cost both in computation…

Computer Vision and Pattern Recognition · Computer Science 2018-11-20 Wenbing Huang , Tong Zhang , Yu Rong , Junzhou Huang

We propose an automated method for detecting aggressive prostate cancer(CaP) (Gleason score >=7) based on a comprehensive analysis of the lesion and the surrounding normal prostate tissue which has been simultaneously captured in…

Computer Vision and Pattern Recognition · Computer Science 2016-12-02 Imon Banerjee , Lewis Hahn , Geoffrey Sonn , Richard Fan , Daniel L. Rubin

Predicting properties of nodes in a graph is an important problem with applications in a variety of domains. Graph-based Semi-Supervised Learning (SSL) methods aim to address this problem by labeling a small subset of the nodes as seeds and…

Machine Learning · Computer Science 2019-02-13 Shikhar Vashishth , Prateek Yadav , Manik Bhandari , Partha Talukdar