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Accurate molecular subtype classification is essential for personalized breast cancer treatment, yet conventional immunohistochemical analysis relies on invasive biopsies and is prone to sampling bias. Although dynamic contrast-enhanced…

Computer Vision and Pattern Recognition · Computer Science 2026-01-13 Sen Zeng , Hong Zhou , Zheng Zhu , Yang Liu

Breast cancer is the most common malignant tumor among women and the second cause of cancer-related death. Early diagnosis in clinical practice is crucial for timely treatment and prognosis. Dynamic contrast-enhanced magnetic resonance…

Image and Video Processing · Electrical Eng. & Systems 2024-05-13 Zixian Li , Yuming Zhong , Yi Wang

An automatic segmentation algorithm for delineation of the gross tumour volume and pathologic lymph nodes of head and neck cancers in PET/CT images is described. The proposed algorithm is based on a convolutional neural network using the…

Image and Video Processing · Electrical Eng. & Systems 2019-08-05 Yngve Mardal Moe , Aurora Rosvoll Groendahl , Martine Mulstad , Oliver Tomic , Ulf Indahl , Einar Dale , Eirik Malinen , Cecilia Marie Futsaether

Deep transfer learning using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) has shown strong predictive power in characterization of breast lesions. However, pretrained convolutional neural networks (CNNs) require 2D inputs,…

Medical Physics · Physics 2019-11-11 Qiyuan Hu , Heather M. Whitney , Maryellen L. Giger

The diagnosis and segmentation of tumors using any medical diagnostic tool can be challenging due to the varying nature of this pathology. Magnetic Reso- nance Imaging (MRI) is an established diagnostic tool for various diseases and…

Computer Vision and Pattern Recognition · Computer Science 2017-11-01 Tanvi Gupta , Pranay Manocha , Tapan K. Gandhi , RK Gupta , BK Panigrahi

Pap smear testing has been widely used for detecting cervical cancers based on the morphology properties of cell nuclei in microscopic image. An accurate nuclei segmentation could thus improve the success rate of cervical cancer screening.…

Computer Vision and Pattern Recognition · Computer Science 2019-05-15 Jie Zhao , Quanzheng Li , Xiang Li , Hongfeng Li , Li Zhang

Dynamic Contrast-enhanced magnetic resonance imaging (DCE-MRI) is a tissue perfusion imaging technique. Some versatile free-breathing DCE-MRI techniques combining compressed sensing (CS) and parallel imaging with golden-angle radial…

Medical Physics · Physics 2020-07-08 Yuhan Hu , Xinlin Zhang , Li Feng , Dicheng Chen , Zhiping Yan , Xiaoyong Shen , Gen Yan , Lin Ou-yang , Xiaobo Qu

Most MRI liver segmentation methods use a structural 3D scan as input, such as a T1 or T2 weighted scan. Segmentation performance may be improved by utilizing both structural and functional information, as contained in dynamic contrast…

Image and Video Processing · Electrical Eng. & Systems 2019-08-23 Mariëlle J. A. Jansen , Hugo J. Kuijf , Josien P. W. Pluim

Magnetic Resonance Imaging (MRI) is essential for noninvasive generation of high-quality images of human tissues. Accurate segmentation of MRI data is critical for medical applications like brain anatomy analysis and disease detection.…

Optimization and Control · Mathematics 2025-10-17 Laura Antonelli , Valentina De Simone , Marco Viola

Deep learning has gained significant attention in medical image segmentation. However, the limited availability of annotated training data presents a challenge to achieving accurate results. In efforts to overcome this challenge, data…

Image and Video Processing · Electrical Eng. & Systems 2024-08-16 Aghiles Kebaili , Jérôme Lapuyade-Lahorgue , Pierre Vera , Su Ruan

Tumor volume segmentation on MRI is a challenging and time-consuming process that is performed manually in typical clinical settings. This work presents an approach to automated delineation of head and neck tumors on MRI scans, developed in…

Image and Video Processing · Electrical Eng. & Systems 2025-01-10 Andrei Iantsen

Inspired by the success of Convolutional Neural Networks (CNN), we develop a novel Computer Aided Detection (CADe) system using CNN for Glioblastoma Multiforme (GBM) detection and segmentation from multi channel MRI data. A two-stage…

Computer Vision and Pattern Recognition · Computer Science 2018-06-21 Subhasis Banerjee , Sushmita Mitra , Anmol Sharma , B. Uma Shankar

Convolutional Neural Networks (CNNs) have been recently employed to solve problems from both the computer vision and medical image analysis fields. Despite their popularity, most approaches are only able to process 2D images while most…

Computer Vision and Pattern Recognition · Computer Science 2016-06-16 Fausto Milletari , Nassir Navab , Seyed-Ahmad Ahmadi

Brain tumors analysis is important in timely diagnosis and effective treatment to cure patients. Tumor analysis is challenging because of tumor morphology like size, location, texture, and heteromorphic appearance in the medical images. In…

Image and Video Processing · Electrical Eng. & Systems 2022-02-14 Mirza Mumtaz Zahoor , Shahzad Ahmad Qureshi , Saddam Hussain Khan , Asifullah Khan

In the field of medical image segmentation, challenges such as indistinct lesion features, ambiguous boundaries,and multi-scale characteristics have long revailed. This paper proposes an improved method named Intensity-Spatial Dual Masked…

Image and Video Processing · Electrical Eng. & Systems 2025-02-17 Yuexing Ding , Jun Wang , Hongbing Lyu

Purpose: To improve the quality of images obtained via dynamic contrast-enhanced MRI (DCE-MRI) that include motion artifacts and blurring using a deep learning approach. Methods: A multi-channel convolutional neural network (MARC) based…

Computer Vision and Pattern Recognition · Computer Science 2020-03-02 Daiki Tamada , Marie-Luise Kromrey , Hiroshi Onishi , Utaroh Motosugi

Molecularly targeted contrast enhanced ultrasound (mCEUS) is a clinically promising approach for early cancer detection through targeted imaging of VEGFR2 (KDR) receptors. We have developed computational enhancement techniques for mCEUS…

Image and Video Processing · Electrical Eng. & Systems 2020-06-23 Andrew A. Berlin , Mon Young , Ahmed El Kaffas , Sam Gambhir , Amelie Lutz , Maria Luigia Storto , Juergen Willmann

Segmentation of colorectal cancerous regions from 3D Magnetic Resonance (MR) images is a crucial procedure for radiotherapy which conventionally requires accurate delineation of tumour boundaries at an expense of labor, time and…

Computer Vision and Pattern Recognition · Computer Science 2021-05-25 Yi-Jie Huang , Qi Dou , Zi-Xian Wang , Li-Zhi Liu , Ying Jin , Chao-Feng Li , Lisheng Wang , Hao Chen , Rui-Hua Xu

As the rapid growth of high-speed and deep-tissue imaging in biomedical research, it is urgent to find a robust and effective denoising method to retain morphological features for further texture analysis and segmentation. Conventional…

Image and Video Processing · Electrical Eng. & Systems 2019-04-16 Sheng-Yong Niu , Lun-Zhang Guo , Yue Li , Tzung-Dau Wang , Yu Tsao , Tzu-Ming Liu

Imaging in clinical oncology trials provides a wealth of information that contributes to the drug development process, especially in early phase studies. This paper focuses on kinetic modeling in DCE-MRI, inspired by mixed-effects models…

Applications · Statistics 2020-04-22 Volker J. Schmid , Brandon Whitcher , Anwar R. Padhani , N. Jane Taylor , Guang-Zhong Yang