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A Bayesian non-parametric framework for studying time-to-event data is proposed, where the prior distribution is allowed to depend on an additional random source, and may update with the sample size. Such scenarios are natural, for…

Methodology · Statistics 2025-05-06 Martin Bladt , Jorge González Cázares

Adaptive experiment is widely adopted to estimate conditional average treatment effect (CATE) in clinical trials and many other scenarios. While the primary goal in experiment is to maximize estimation accuracy, due to the imperative of…

Methodology · Statistics 2024-02-06 Jiachun Li , Kaining Shi , David Simchi-Levi

Causal discovery is to learn cause-effect relationships among variables given observational data and is important for many applications. Existing causal discovery methods assume data sufficiency, which may not be the case in many real world…

Machine Learning · Computer Science 2022-06-20 Zijun Cui , Naiyu Yin , Yuru Wang , Qiang Ji

We recently developed a new method riAFT-BART to draw causal inferences about population treatment effect on patient survival from clustered and censored survival data while accounting for the multilevel data structure. The practical…

Methodology · Statistics 2023-08-14 Liangyuan Hu

The recently proposed statistical finite element (statFEM) approach synthesises measurement data with finite element models and allows for making predictions about the unknown true system response. We provide a probabilistic error analysis…

Statistics Theory · Mathematics 2025-06-17 Toni Karvonen , Fehmi Cirak , Mark Girolami

The purpose of this paper is to provide guidelines for empirical researchers who use a class of bivariate threshold crossing models with dummy endogenous variables. A common practice employed by the researchers is the specification of the…

Econometrics · Economics 2019-03-06 Sukjin Han , Sungwon Lee

Given the cost and duration of phase III and phase IV clinical trials, the development of statistical methods for go/no-go decisions is vital. In this paper, we introduce a Bayesian methodology to compute the probability of success based on…

Methodology · Statistics 2020-10-27 Ethan M. Alt , Matthew A. Psioda , Joseph G. Ibrahim

Time series data provided by single-molecule Forster resonance energy transfer (sm-FRET) experiments offer the opportunity to infer not only model parameters describing molecular complexes, e.g. rate constants, but also information about…

Quantitative Methods · Quantitative Biology 2015-05-13 Jonathan E. Bronson , Jingyi Fei , Jake M. Hofman , Ruben L. Gonzalez, , Chris H. Wiggins

Safety evaluation is an essential component of clinical trials. To protect study participants, these studies often implement safety stopping rules that will halt the trial if an excessive number of toxicity events occur. Existing safety…

Methodology · Statistics 2025-10-06 Michael J. Martens , Qinghua Lian , Brent R. Logan

Bayesian Causal Forests (BCF) is a causal inference machine learning model based on a highly flexible non-parametric regression and classification tool called Bayesian Additive Regression Trees (BART). Motivated by data from the Trends in…

Machine Learning · Statistics 2023-03-10 Nathan McJames , Andrew Parnell , Yong Chen Goh , Ann O'Shea

A model-assisted semiparametric method of estimating finite population totals is investigated to improve the precision of survey estimators by incorporating multivariate auxiliary information. The proposed superpopulation model is a…

Methodology · Statistics 2019-03-19 Lily Wang

Data increasingly take the form of a multi-way array, or tensor, in several biomedical domains. Such tensors are often incompletely observed. For example, we are motivated by longitudinal microbiome studies in which several timepoints are…

Methodology · Statistics 2024-11-01 Ziren Jiang , Gen Li , Eric F. Lock

We have used Bayesian Optimisation (BO) to find hyper-parameters in an existing biologically plausible population neural network. The 8-dimensional optimal hyper-parameter combination should be such that the network dynamics simulate the…

Quantitative Methods · Quantitative Biology 2021-04-14 Mahak Kothari , Swapna Sasi , Jun Chen , Elham Zareian , Basabdatta Sen Bhattacharya

This paper develops a finite population framework for analyzing causal effects in settings with imperfect compliance where multiple treatments affect the outcome of interest. Two prominent examples are factorial designs and panel…

Methodology · Statistics 2026-01-26 Pedro Picchetti

Accurate force fields are essential for reliable molecular simulations. These models are refined against quantum mechanical calculations and experimental measurements, which are subject to random and systematic errors. Bayesian Inference of…

Chemical Physics · Physics 2025-11-04 Robert M. Raddi , Vincent A. Voelz

Bayesian model-averaged meta-analysis allows quantification of evidence for both treatment effectiveness $\mu$ and across-study heterogeneity $\tau$. We use the Cochrane Database of Systematic Reviews to develop discipline-wide empirical…

We propose some extensions to semi-parametric models based on Bayesian additive regression trees (BART). In the semi-parametric BART paradigm, the response variable is approximated by a linear predictor and a BART model, where the linear…

Machine Learning · Statistics 2026-03-10 Estevão B. Prado , Andrew C. Parnell , Keefe Murphy , Nathan McJames , Ann O'Shea , Rafael A. Moral

The Family Planning Estimation Tool (FPET) is used in low- and middle-income countries to produce estimates and short-term forecasts of family planning indicators, such as modern contraceptive use and unmet need for contraceptives.…

Accurate and timely population data are essential for disaster response and humanitarian planning, but traditional censuses often cannot capture rapid demographic changes. Social media data offer a promising alternative for dynamic…

We propose an approximate hierarchical Bayes approach that uses the Natural Exponential Family with Quadratic Variance Function in combining information from multiple sources to improve traditional survey estimates of finite population…

Methodology · Statistics 2025-12-25 Soumojit Das , Partha Lahiri
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