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For nearly any challenging scientific problem evaluation of the likelihood is problematic if not impossible. Approximate Bayesian computation (ABC) allows us to employ the whole Bayesian formalism to problems where we can use simulations…

Computation · Statistics 2011-07-04 Chris Barnes , Sarah Filippi , Michael P. H. Stumpf , Thomas Thorne

Mathematical models are invaluable for understanding and predicting how biological systems behave, although their construction requires specifying mechanisms and relationships that are often not perfectly known. In the presence of multiple…

Infectious disease remains, despite centuries of work to control and mitigate its effects, a major problem facing humanity. This paper reviews the mathematical modelling of infectious disease epidemics on networks, starting from the…

Popular Physics · Physics 2015-06-03 Thomas House

Wildlife disease surveillance programs and research studies track infection and identify risk factors for wild populations, humans, and agriculture. Often, several types of samples are collected from individuals to provide more complete…

Bayesian estimation is a powerful theoretical paradigm for the operation of quantum sensors. However, the Bayesian method for statistical inference generally suffers from demanding calibration requirements that have so far restricted its…

Quantum Physics · Physics 2021-09-22 Samuel P. Nolan , Augusto Smerzi , Luca Pezzè

The Bayesian approach to data analysis provides a powerful way to handle uncertainty in all observations, model parameters, and model structure using probability theory. Probabilistic programming languages make it easier to specify and fit…

Modeling the spread of infections on networks is a well-studied and important field of research. Most infection and diffusion models require a real value or probability on the edges of the network as an input, but this is rarely available…

Social and Information Networks · Computer Science 2017-06-26 Andras Bota , Lauren Gardner

Chain Event Graphs (CEGs) are a widely applicable class of probabilistic graphical model that can represent context-specific independence statements and asymmetric unfoldings of events in an easily interpretable way. Existing model…

Methodology · Statistics 2022-06-20 Peter Strong , Jim Q Smith

Recent work has focused attention on statistical inference for the population distribution of the number of sexual partners based on survey data. The characteristics of these distributions are of interest as components of mathematical…

Disordered Systems and Neural Networks · Physics 2007-05-23 Mark S. Handcock , James Holland Jones , Martina Morris

The analysis of multivariate functional curves has the potential to yield important scientific discoveries in domains such as healthcare, medicine, economics and social sciences. However, it is common for real-world settings to present…

Methodology · Statistics 2024-07-23 Tui Nolan , Sylvia Richardson , Hélène Ruffieux

Background: Recently developed techniques to study the spread of infectious diseases through networks make assumptions that the initial proportion infected is infinitesimal and the population behavior is static throughout the epidemic. The…

Populations and Evolution · Quantitative Biology 2012-08-17 Joel C. Miller

We study several bayesian inference problems for irreversible stochastic epidemic models on networks from a statistical physics viewpoint. We derive equations which allow to accurately compute the posterior distribution of the time…

Quantitative Methods · Quantitative Biology 2014-03-28 Fabrizio Altarelli , Alfredo Braunstein , Luca Dall'Asta , Alejandro Lage-Castellanos , Riccardo Zecchina

Mathematical modeling of disease outbreaks can infer the future trajectory of an epidemic, which can inform policy decisions. Another task is inferring the origin of a disease, which is relatively difficult with current mathematical models.…

Physics and Society · Physics 2022-08-31 Mehrad Ansari , David Soriano-Paños , Gourab Ghoshal , Andrew D. White

To be fully useful for public health practice, models for epidemic response must be able to do more than predict -- it is also important to incorporate the mechanisms underlying transmission dynamics to enable policymakers and practitioners…

Quantitative Methods · Quantitative Biology 2025-05-26 Jiale Tan , Marisa C. Eisenberg

The analysis of population-wide datasets can provide insight on the health status of large populations so that public health officials can make data-driven decisions. The analysis of such datasets often requires highly parameterized models…

Applications · Statistics 2021-02-03 Dorota Młynarczyk , Carmen Armero , Virgilio Gómez-Rubio , Pedro Puig

The humanity has been facing a plethora of challenges associated with infectious diseases, which kill more than 6 million people a year. Although continuous efforts have been applied to relieve the potential damages from such misfortunate…

Artificial Intelligence · Computer Science 2019-05-07 Cheol Young Park , Shou Matsumoto , Jubyung Ha , YoungWon Park

Bayesian modeling helps applied researchers articulate assumptions about their data and develop models tailored for specific applications. Thanks to good methods for approximate posterior inference, researchers can now easily build, use,…

Methodology · Statistics 2023-11-22 Gemma E. Moran , David M. Blei , Rajesh Ranganath

Epidemic models are powerful tools in understanding infectious disease. However, as they increase in size and complexity, they can quickly become computationally intractable. Recent progress in modelling methodology has shown that surrogate…

Machine Learning · Computer Science 2023-03-13 Giovanni Charles , Timothy M. Wolock , Peter Winskill , Azra Ghani , Samir Bhatt , Seth Flaxman

The early detection of infectious disease outbreaks is a crucial task to protect population health. To this end, public health surveillance systems have been established to systematically collect and analyse infectious disease data. A…

Applications · Statistics 2019-02-27 Benedikt Zacher , Irina Czogiel

Continuous time Bayesian networks are investigated with a special focus on their ability to express causality. A framework is presented for doing inference in these networks. The central contributions are a representation of the intensity…

Machine Learning · Statistics 2016-01-26 Jonas Hallgren , Timo Koski