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We investigate the information-theoretical limits of inference tasks in epidemic spreading on graphs in the thermodynamic limit. The typical inference tasks consist in computing observables of the posterior distribution of the epidemic…

Physics and Society · Physics 2023-12-25 Alfredo Braunstein , Louise Budzynski , Matteo Mariani

There is no consensus in the field of synthetic data on concise metrics for quality evaluations or benchmarks on large health datasets, such as historical epidemiological data. This study presents an evaluation of seven recent models from…

Machine Learning · Computer Science 2026-04-20 Jean-Baptiste Escudié , Benjamin Barnes , Stefan Meisegeier , Klaus Kraywinkel , Fabian Prasser , Nils Körber

Spatial connectivity is an important consideration when modelling infectious disease data across a geographical region. Connectivity can arise for many reasons, including shared characteristics between regions, and human or vector movement.…

Methodology · Statistics 2022-06-06 Sophie A Lee , Theodoros Economou , Rachel Lowe

Due to increased awareness of data protection and corresponding laws many data, especially involving sensitive personal information, are not publicly accessible. Accordingly, many data collecting agencies only release aggregated data, e.g.…

Methodology · Statistics 2022-04-12 Rajbir-Singh Nirwan , Nils Bertschinger

Network-based models of epidemic spread have become increasingly popular in recent decades. Despite a rich foundation of such models, few low-dimensional systems for modeling SIS-type diseases have been proposed that manage to capture the…

Dynamical Systems · Mathematics 2021-01-01 Carl Corcoran , Alan Hastings

Safe and reliable disclosure of information from confidential data is a challenging statistical problem. A common approach considers the generation of synthetic data, to be disclosed instead of the original data. Efficient approaches ought…

Methodology · Statistics 2024-03-04 Larissa N. A. Martins , Flávio B. Gonçalves , Thais P. Galletti

In recent years, disease mapping studies have become a routine application within geographical epidemiology and are typically analysed within a Bayesian hierarchical model formulation. A variety of model formulations for the latent level…

Methodology · Statistics 2016-01-07 Andrea Riebler , Sigrunn H. Sørbye , Daniel Simpson , Håvard Rue

Epidemiological models describe the spread of an infectious disease within a population. They capture microscopic details on how the disease is passed on among individuals in various different ways, while making predictions about the state…

Populations and Evolution · Quantitative Biology 2024-02-27 Stefan Hohenegger , Francesco Sannino

The COVID-19 pandemic provides new motivation for a classic problem in epidemiology: estimating the empirical rate of transmission during an outbreak (formally, the time-varying reproduction number) from case counts. While standard methods…

Methodology · Statistics 2020-12-08 Bryan Wilder , Michael J. Mina , Milind Tambe

The COronaVIrus Disease 2019 (COVID-19) pandemic that has had the world in its grip from the beginning of 2020, has resulted in an unprecedented level of public interest and media attention on the field of mathematical epidemiology. Ever…

Other Quantitative Biology · Quantitative Biology 2022-03-25 Sitabhra Sinha

Computationally expensive simulators, implementing mathematical models in computer codes, are commonly approximated using statistical emulators. We develop and assess novel emulation methods for systems best modelled via a chain, series or…

Methodology · Statistics 2021-08-26 Samuel E. Jackson , David C. Woods

Infectious disease modeling is used to forecast epidemics and assess the effectiveness of intervention strategies. Although the core assumption of mass-action models of homogeneously mixed population is often implausible, they are…

Physics and Society · Physics 2024-08-29 Thien-Minh Le , Jukka-Pekka Onnela

Stochasticity and spatial heterogeneity are of great interest recently in studying the spread of an infectious disease. The presented method solves an inverse problem to discover the effectively decisive topology of a heterogeneous network…

Artificial Intelligence · Computer Science 2015-03-13 Yoshiharu Maeno

Nonlinear mixed effects models have become a standard platform for analysis when data is in the form of continuous and repeated measurements of subjects from a population of interest, while temporal profiles of subjects commonly follow a…

Methodology · Statistics 2022-03-04 Se Yoon Lee

Datasets are rarely a realistic approximation of the target population. Say, prevalence is misrepresented, image quality is above clinical standards, etc. This mismatch is known as sampling bias. Sampling biases are a major hindrance for…

The epidemic threshold is probably the most studied quantity in the modelling of epidemics on networks. For a large class of networks and dynamics the epidemic threshold is well studied and understood. However, it is less so for clustered…

Physics and Society · Physics 2018-06-19 Rosanna C. Barnard , Luc Berthouze , Péter L. Simon , István Z. Kiss

Deterministic compartmental models are predominantly used in the modeling of infectious diseases, though stochastic models are considered more realistic, yet are complicated to estimate due to missing data. In this paper we present a novel…

Computation · Statistics 2022-06-22 Shuying Wang , Stephen G. Walker

Understanding the spread of any disease is a highly complex and interdisciplinary exercise as biological, social, geographic, economic, and medical factors may shape the way a disease moves through a population and options for its eventual…

Populations and Evolution · Quantitative Biology 2016-12-14 Aristides Moustakas

Complex data features, such as unmodelled censored event times and variables with time-dependent effects, are common in cancer recurrence studies and pose challenges for Bayesian survival modelling. Current methodologies for predictive…

Methodology · Statistics 2026-01-12 Saku Suorsa , Aki Vehtari

A Bayesian network is a graphical model that encodes probabilistic relationships among variables of interest. When used in conjunction with statistical techniques, the graphical model has several advantages for data analysis. One, because…

Machine Learning · Computer Science 2022-01-11 David Heckerman
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