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Evidence suggests Rapid-Eye-Movement (REM) Sleep Behaviour Disorder (RBD) is an early predictor of Parkinson's disease. This study proposes a fully-automated framework for RBD detection consisting of automated sleep staging followed by RBD…

Machine Learning · Computer Science 2018-11-13 Navin Cooray , Fernando Andreotti , Christine Lo , Mkael Symmonds , Michele T. M. Hu , Maarten De Vos

Isolated rapid eye movement sleep behavior disorder (iRBD) is a major prodromal marker of $\alpha$-synucleinopathies, often preceding the clinical onset of Parkinson's disease, dementia with Lewy bodies, or multiple system atrophy. While…

Isolated REM sleep behavior disorder (iRBD) is a key prodromal marker of Parkinson's disease (PD), and video-polysomnography (vPSG) remains the diagnostic gold standard. However, manual sleep staging is particularly challenging in…

Numerous sleep disorders are characterised by movement during sleep, these include rapid-eye movement sleep behaviour disorder (RBD) and periodic limb movement disorder. The process of diagnosing movement related sleep disorders requires…

Quantitative Methods · Quantitative Biology 2023-02-16 Navin Cooray , Zhenglin Li , Jinzhuo Wang , Christine Lo , Mahnaz Arvaneh , Mkael Symmonds , Michele Hu , Maarten De Vos , Lyudmila S Mihaylova

Parkinson's disease (PD), a severe and progressive neurological illness, affects millions of individuals worldwide. For effective treatment and management of PD, an accurate and early diagnosis is crucial. This study presents a deep…

Signal Processing · Electrical Eng. & Systems 2023-08-16 Niloufar Delfan , Mohammadreza Shahsavari , Sadiq Hussain , Robertas Damaševičius , U. Rajendra Acharya

Resting-state EEG (rs-EEG) has been demonstrated to aid in Parkinson's disease (PD) diagnosis. In particular, the power spectral density (PSD) of low-frequency bands ({\delta} and {\theta}) and high-frequency bands ({\alpha} and \b{eta})…

Signal Processing · Electrical Eng. & Systems 2023-03-03 Anna Kurbatskaya , Alberto Jaramillo-Jimenez , John Fredy Ochoa-Gomez , Kolbjørn Brønnick , Alvaro Fernandez-Quilez

Parkinsons Disease (PD) is a neurodegenerative disorder resulting in motor deficits due to advancing degeneration of dopaminergic neurons. PD patients report experiencing tremor, rigidity, visual impairment, bradykinesia, and several…

Computer Vision and Pattern Recognition · Computer Science 2023-04-05 Krish Desai

In universal environment, a patient-friendly inexpensive method is needed to realize the early diagnosis of depression, which is believed to be an effective way to reduce the mortality of depression. The purpose of this study is only to…

Signal Processing · Electrical Eng. & Systems 2020-02-28 Qiuxia Shi , Ang Liu , Rongyan Chen , Jian Shen , Qinglin Zhao , Bin Hu

Parkinson's disease (PD) is one of the major public health problems in the world. It is a well-known fact that around one million people suffer from Parkinson's disease in the United States whereas the number of people suffering from…

Machine Learning · Computer Science 2016-10-27 Kamal Nayan Reddy Challa , Venkata Sasank Pagolu , Ganapati Panda , Babita Majhi

Preclinical sleep research remains constrained by labor intensive, manual vigilance state classification and inter rater variability, limiting throughput and reproducibility. This study presents an automated framework developed by Team…

Signal Processing · Electrical Eng. & Systems 2025-07-22 Sankalp Jajee , Gaurav Kumar , Homayoun Valafar

One of the most catastrophic neurological disorders worldwide is Parkinson's Disease. Along with it, the treatment is complicated and abundantly expensive. The only effective action to control the progression is diagnosing it in the early…

Machine Learning · Computer Science 2023-10-23 Md. Taufiqul Haque Khan Tusar , Md. Touhidul Islam , Abul Hasnat Sakil

In the status quo, dementia is yet to be cured. Precise diagnosis prior to the onset of the symptoms can prevent the rapid progression of the emerging cognitive impairment. Recent progress has shown that Electroencephalography (EEG) is the…

In this paper, we aimed at reviewing several different approaches present today in the search for more accurate diagnostic and treatment management in mental healthcare. Our focus is on mood disorders, and in particular on the major…

Neurons and Cognition · Quantitative Biology 2019-03-28 Milena Cukic Radenkovic

In this paper, we propose a novel method and a practical approach to predicting early onsets of sleep syndromes, including restless leg syndrome, insomnia, based on an algorithm that is comprised of two modules. A Fast Fourier Transform is…

Neurons and Cognition · Quantitative Biology 2021-07-09 Tim Cvetko , Tinkara Robek

As sleep disorders are becoming more prevalent there is an urgent need to classify sleep stages in a less disturbing way.In particular, sleep-stage classification using simple sensors, such as single-channel electroencephalography (EEG),…

Signal Processing · Electrical Eng. & Systems 2023-02-27 Iksoo Choi , Wonyong Sung

Understanding the sleep quality and architecture is essential to human being's health, which is usually represented using multiple sleep stages. A standard sleep stage determination requires Electroencephalography (EEG) signals during the…

Signal Processing · Electrical Eng. & Systems 2019-09-26 Yuezhou Zhang , Zhicheng Yang , Ke Lan , Xiaoli Liu , Zhengbo Zhang , Peiyao Li , Desen Cao , Jiewen Zheng , Jianli Pan

Accurate sleep stage classification is essential for diagnosing sleep disorders, particularly in aging populations. While traditional polysomnography (PSG) relies on electroencephalography (EEG) as the gold standard, its complexity and need…

Computer Vision and Pattern Recognition · Computer Science 2025-06-10 Olivier Papillon , Rafik Goubran , James Green , Julien Larivière-Chartier , Caitlin Higginson , Frank Knoefel , Rébecca Robillard

Diagnosing sleep disorders is an important focus in neuroscience and engineering, as these conditions involve issues such as insufficient sleep, frequent awakenings, and difficulty reaching deep sleep. Accurate detection based on brain…

Neurons and Cognition · Quantitative Biology 2025-09-03 Mohammad Reza Yousefi , Reza Rahimi

The brain electrical activity presents several short events during sleep that can be observed as distinctive micro-structures in the electroencephalogram (EEG), such as sleep spindles and K-complexes. These events have been associated with…

Signal Processing · Electrical Eng. & Systems 2020-10-06 Nicolás I. Tapia , Pablo A. Estévez

Sleep studies are imperative to recapitulate phenotypes associated with sleep loss and uncover mechanisms contributing to psychopathology. Most often, investigators manually classify the polysomnography into vigilance states, which is…

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