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The scarcity of labeled data is a major bottleneck for developing accurate and robust deep learning-based models for histopathology applications. The problem is notably prominent for the task of metastasis detection in lymph nodes, due to…

Image and Video Processing · Electrical Eng. & Systems 2021-09-21 Apostolia Tsirikoglou , Karin Stacke , Gabriel Eilertsen , Jonas Unger

Digitization of histopathology slides has led to several advances, from easy data sharing and collaborations to the development of digital diagnostic tools. Deep learning (DL) methods for classification and detection have shown great…

Image and Video Processing · Electrical Eng. & Systems 2020-05-25 Apostolia Tsirikoglou , Karin Stacke , Gabriel Eilertsen , Martin Lindvall , Jonas Unger

Assessing the presence of potentially malignant lymph nodes aids in estimating cancer progression, and identifying surrounding benign lymph nodes can assist in determining potential metastatic pathways for cancer. For quantitative analysis,…

Computer Vision and Pattern Recognition · Computer Science 2025-04-16 Litingyu Wang , Yijie Qu , Xiangde Luo , Wenjun Liao , Shichuan Zhang , Guotai Wang

Deep learning (DL) has proven highly effective for ultrasound-based computer-aided diagnosis (CAD) of breast cancers. In an automaticCAD system, lesion detection is critical for the following diagnosis. However, existing DL-based methods…

Image and Video Processing · Electrical Eng. & Systems 2023-06-13 Jian Wang , Liang Qiao , Shichong Zhou , Jin Zhou , Jun Wang , Juncheng Li , Shihui Ying , Cai Chang , Jun Shi

Pathologists find tedious to examine the status of the sentinel lymph node on a large number of pathological scans. The examination process of such lymph node which encompasses metastasized cancer cells is histopathologically organized.…

Computer Vision and Pattern Recognition · Computer Science 2019-06-25 Amit Kumar Jaiswal , Ivan Panshin , Dimitrij Shulkin , Nagender Aneja , Samuel Abramov

Metastasis on lymph nodes (LNs), the most common way of spread for primary tumor cells, is a sign of increased mortality. However, metastatic LNs are time-consuming and challenging to detect even for professional radiologists due to their…

Image and Video Processing · Electrical Eng. & Systems 2023-01-10 Chaoyi Wu , Feng Chang , Xiao Su , Zhihan Wu , Yanfeng Wang , Ling Zhu , Ya Zhang

Pathological lymph node delineation is crucial in cancer diagnosis, progression assessment, and treatment planning. The MICCAI 2023 Lymph Node Quantification Challenge published the first public dataset for pathological lymph node…

Computer Vision and Pattern Recognition · Computer Science 2024-06-24 Stefan M. Fischer , Johannes Kiechle , Daniel M. Lang , Jan C. Peeken , Julia A. Schnabel

Computer aided diagnostics often requires analysis of a region of interest (ROI) within a radiology scan, and the ROI may be an organ or a suborgan. Although deep learning algorithms have the ability to outperform other methods, they rely…

Image and Video Processing · Electrical Eng. & Systems 2021-12-08 Sankaran Iyer , Alan Blair , Laughlin Dawes , Daniel Moses , Christopher White , Arcot Sowmya

Lymph node (LN) metastasis status is one of the most critical prognostic and cancer staging factors for patients with resectable pancreatic ductal adenocarcinoma (PDAC), or in general, for any types of solid malignant tumors. Preoperative…

Image and Video Processing · Electrical Eng. & Systems 2023-01-05 Zhilin Zheng , Xu Fang , Jiawen Yao , Mengmeng Zhu , Le Lu , Lingyun Huang , Jing Xiao , Yu Shi , Hong Lu , Jianping Lu , Ling Zhang , Chengwei Shao , Yun Bian

The evaluation of lymph node metastases plays a crucial role in achieving precise cancer staging, influencing subsequent decisions regarding treatment options. Lymph node detection poses challenges due to the presence of unclear boundaries…

Computer Vision and Pattern Recognition · Computer Science 2024-06-07 Sofija Engelson , Jan Ehrhardt , Timo Kepp , Joshua Niemeijer , Heinz Handels

Breast cancer is a major concern for women's health globally, with axillary lymph node (ALN) metastasis identification being critical for prognosis evaluation and treatment guidance. This paper presents a deep learning (DL) classification…

Image and Video Processing · Electrical Eng. & Systems 2023-10-09 Glejdis Shkëmbi , Johanna P. Müller , Zhe Li , Katharina Breininger , Peter Schüffler , Bernhard Kainz

Multi-modal Learning has attracted widespread attention in medical image analysis. Using multi-modal data, whole slide images (WSIs) and clinical information, can improve the performance of deep learning models in the diagnosis of axillary…

Image and Video Processing · Electrical Eng. & Systems 2024-01-04 Shichuan Zhang , Sunyi Zheng , Zhongyi Shui , Honglin Li , Lin Yang

Deep learning classifiers for characterization of whole slide tissue morphology require large volumes of annotated data to learn variations across different tissue and cancer types. As is well known, manual generation of digital pathology…

Image and Video Processing · Electrical Eng. & Systems 2019-07-10 Shahira Abousamra , Le Hou , Rajarsi Gupta , Chao Chen , Dimitris Samaras , Tahsin Kurc , Rebecca Batiste , Tianhao Zhao , Shroyer Kenneth , Joel Saltz

Automatic lymph node segmentation is the cornerstone for advances in computer vision tasks for early detection and staging of cancer. Traditional segmentation methods are constrained by manual delineation and variability in operator…

Image and Video Processing · Electrical Eng. & Systems 2025-06-11 Jingguo Qu , Xinyang Han , Man-Lik Chui , Yao Pu , Simon Takadiyi Gunda , Ziman Chen , Jing Qin , Ann Dorothy King , Winnie Chiu-Wing Chu , Jing Cai , Michael Tin-Cheung Ying

Understanding the progression of cancer is crucial for defining treatments for patients. The objective of this study is to automate the detection of metastatic liver disease from free-style computed tomography (CT) radiology reports. Our…

Machine Learning · Computer Science 2023-10-31 Maede Ashofteh Barabadi , Xiaodan Zhu , Wai Yip Chan , Amber L. Simpson , Richard K. G. Do

Training a neural network with a large labeled dataset is still a dominant paradigm in computational histopathology. However, obtaining such exhaustive manual annotations is often expensive, laborious, and prone to inter and Intra-observer…

Computer Vision and Pattern Recognition · Computer Science 2021-11-03 Chetan L. Srinidhi , Seung Wook Kim , Fu-Der Chen , Anne L. Martel

This work is an endeavor to develop a deep learning methodology for automated anatomical labeling of a given region of interest (ROI) in brain computed tomography (CT) scans. We combine both local and global context to obtain a…

Computer Vision and Pattern Recognition · Computer Science 2018-01-23 Srikrishna Varadarajan , Muktabh Mayank Srivastava , Monika Grewal , Pulkit Kumar

Recently, large, high-quality public datasets have led to the development of convolutional neural networks that can detect lymph node metastases of breast cancer at the level of expert pathologists. Many cancers, regardless of the site of…

Image and Video Processing · Electrical Eng. & Systems 2022-07-14 Péter Bándi , Maschenka Balkenhol , Marcory van Dijk , Bram van Ginneken , Jeroen van der Laak , Geert Litjens

Analysis of histopathology slides is a critical step for many diagnoses, and in particular in oncology where it defines the gold standard. In the case of digital histopathological analysis, highly trained pathologists must review vast…

Computer Vision and Pattern Recognition · Computer Science 2020-02-21 Pierre Courtiol , Eric W. Tramel , Marc Sanselme , Gilles Wainrib

This study presents an unsupervised domain adaptation method aimed at autonomously generating image masks outlining regions of interest (ROIs) for differentiating breast lesions in breast ultrasound (US) imaging. Our semi-supervised…

Computer Vision and Pattern Recognition · Computer Science 2024-04-22 Ting-Ruen Wei , Michele Hell , Dang Bich Thuy Le , Aren Vierra , Ran Pang , Mahesh Patel , Young Kang , Yuling Yan
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