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This work proposes a novel framework for analyzing disease progression using time-aware neural ordinary differential equations (NODE). We introduce a "time-aware head" in a framework trained through self-supervised learning (SSL) to…

Convolutional Neural Network models have successfully detected retinal illness from optical coherence tomography (OCT) and fundus images. These CNN models frequently rely on vast amounts of labeled data for training, difficult to obtain,…

Computer Vision and Pattern Recognition · Computer Science 2022-01-28 Sourya Dipta Das , Saikat Dutta , Nisarg A. Shah , Dwarikanath Mahapatra , Zongyuan Ge

Medical imaging data suffers from the limited availability of annotation because annotating 3D medical data is a time-consuming and expensive task. Moreover, even if the annotation is available, supervised learning-based approaches suffer…

Image and Video Processing · Electrical Eng. & Systems 2020-11-12 Abinav Ravi Venkatakrishnan , Seong Tae Kim , Rami Eisawy , Franz Pfister , Nassir Navab

This study introduces a groundbreaking optical coherence tomography (OCT) imaging system dedicated for high-throughput screening applications using ex vivo tissue culture. Leveraging OCT's non-invasive, high-resolution capabilities, the…

Accurate assessment of spheno-occipital synchondrosis (SOS) maturation is a key indicator of craniofacial growth and a critical determinant for orthodontic and surgical timing. However, SOS staging from cone-beam CT (CBCT) relies on subtle,…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Omid Halimi Milani , Amanda Nikho , Marouane Tliba , Lauren Mills , Emadeldeen Hamdan , Ahmet Enis Cetin , Mohammed H. Elnagar

Algorithmic image-based diagnosis and prognosis of neurodegenerative diseases on longitudinal data has drawn great interest from computer vision researchers. The current state-of-the-art models for many image classification tasks are based…

Computer Vision and Pattern Recognition · Computer Science 2017-09-04 Jie Zhang , Qingyang Li , Richard J. Caselli , Jieping Ye , Yalin Wang

The ability to predict the future trajectory of a patient is a key step toward the development of therapeutics for complex diseases such as Alzheimer's disease (AD). However, most machine learning approaches developed for prediction of…

Optical Coherence Tomography (OCT) is a non-invasive imaging modality essential for diagnosing various eye diseases. Despite its clinical significance, developing OCT-based diagnostic tools faces challenges, such as limited public datasets,…

Computer Vision and Pattern Recognition · Computer Science 2025-01-30 Mohammadreza Saraei , Igor Kozak , Eung-Joo Lee

Optical coherence tomography (OCT) has stimulated a wide range of medical image-based diagnosis and treatment in fields such as cardiology and ophthalmology. Such applications can be further facilitated by deep learning-based…

Medical Physics · Physics 2023-07-24 Xueshen Li , Zhenxing Dong , Hongshan Liu , Jennifer J. Kang-Mieler , Yuye Ling , Yu Gan

Three-dimensional (3D) medical images, such as Computed Tomography (CT) and Magnetic Resonance Imaging (MRI), are essential for clinical applications. However, the need for diverse and comprehensive representations is particularly…

Computer Vision and Pattern Recognition · Computer Science 2025-05-26 Siwen Wang , Churan Wang , Fei Gao , Lixian Su , Fandong Zhang , Yizhou Wang , Yizhou Yu

Optical coherence tomography (OCT) is a commonly-used method of extracting high resolution retinal information. Moreover there is an increasing demand for the automated retinal layer segmentation which facilitates the retinal disease…

Image and Video Processing · Electrical Eng. & Systems 2020-09-30 Zeyu Fu , Yang Sun , Xiangyu Zhang , Scott Stainton , Shaun Barney , Jeffry Hogg , William Innes , Satnam Dlay

Deep learning has transformed computer vision but relies heavily on large labeled datasets and computational resources. Transfer learning, particularly fine-tuning pretrained models, offers a practical alternative; however, models…

Computer Vision and Pattern Recognition · Computer Science 2025-05-23 Iván Matas , Carmen Serrano , Miguel Nogales , David Moreno , Lara Ferrándiz , Teresa Ojeda , Begoña Acha

The automatic detection of disease related entities in retinal imaging data is relevant for disease- and treatment monitoring. It enables the quantitative assessment of large amounts of data and the corresponding study of disease…

This work explores the effectiveness of masked image modelling for learning representations of retinal OCT images. To this end, we leverage Masked Autoencoders (MAE), a simple and scalable method for self-supervised learning, to obtain a…

Computer Vision and Pattern Recognition · Computer Science 2024-05-24 Theodoros Pissas , Pablo Márquez-Neila , Sebastian Wolf , Martin Zinkernagel , Raphael Sznitman

Longitudinal MRIs are often used to capture the gradual deterioration of brain structure and function caused by aging or neurological diseases. Analyzing this data via machine learning generally requires a large number of ground-truth…

Computer Vision and Pattern Recognition · Computer Science 2021-06-21 Jiahong Ouyang , Qingyu Zhao , Ehsan Adeli , Edith V Sullivan , Adolf Pfefferbaum , Greg Zaharchuk , Kilian M Pohl

This work presents a novel label-efficient selfsupervised representation learning-based approach for classifying diabetic retinopathy (DR) images in cross-domain settings. Most of the existing DR image classification methods are based on…

Image and Video Processing · Electrical Eng. & Systems 2023-04-25 Ekta Gupta , Varun Gupta , Muskaan Chopra , Prakash Chandra Chhipa , Marcus Liwicki

Segmentation of retinal layers from Optical Coherence Tomography (OCT) volumes is a fundamental problem for any computer aided diagnostic algorithm development. This requires preprocessing steps such as denoising, region of interest…

Computer Vision and Pattern Recognition · Computer Science 2018-06-26 Karthik Gopinath , Samrudhdhi B Rangrej , Jayanthi Sivaswamy

The ultra-wide optical coherence tomography angiography (OCTA) has become an important imaging modality in diabetic retinopathy (DR) diagnosis. However, there are few researches focusing on automatic DR analysis using ultra-wide OCTA. In…

Image and Video Processing · Electrical Eng. & Systems 2022-10-04 Junlin Hou , Fan Xiao , Jilan Xu , Yuejie Zhang , Haidong Zou , Rui Feng

In this paper, we propose a deep generative time series approach using latent temporal processes for modeling and holistically analyzing complex disease trajectories. We aim to find meaningful temporal latent representations of an…

Forecasting motion of a specific target object is a common problem for surgical interventions, e.g. for localization of a target region, guidance for surgical interventions, or motion compensation. Optical coherence tomography (OCT) is an…

Image and Video Processing · Electrical Eng. & Systems 2020-06-02 Marcel Bengs , Nils Gessert , Alexander Schlaefer
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