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In recent years, machine learning-based clinical decision support systems (CDSS) have played a key role in the analysis of several medical conditions. Despite their promising capabilities, the lack of transparency in AI models poses…
Lymph node metastasis (LNM) is a significant prognostic factor in patients with head and neck cancer, and the ability to predict it accurately is essential for treatment optimization. PET and CT imaging are routinely used for LNM…
Artificial intelligence (AI) enabled radiomics has evolved immensely especially in the field of oncology. Radiomics provide assistancein diagnosis of cancer, planning of treatment strategy, and predictionof survival. Radiomics in…
We present a hybrid algorithm to estimate lung nodule malignancy that combines imaging biomarkers from Radiologist's annotation with image classification of CT scans. Our algorithm employs a 3D Convolutional Neural Network (CNN) as well as…
Computer Aided Diagnosis has emerged as an indispensible technique for validating the opinion of radiologists in CT interpretation. This paper presents a deep 3D Convolutional Neural Network (CNN) architecture for automated CT scan-based…
Despite the unprecedented performance of deep neural networks (DNNs) in computer vision, their practical application in the diagnosis and prognosis of cancer using medical imaging has been limited. One of the critical challenges for…
Lymph node metastasis (LNM) is a significant prognostic factor in patients with head and neck cancer, and the ability to predict it accurately is essential for treatment optimization. PET and CT imaging are routinely used for LNM…
Lung cancer is the leading cause for cancer related deaths. As such, there is an urgent need for a streamlined process that can allow radiologists to provide diagnosis with greater efficiency and accuracy. A powerful tool to do this is…
Timely brain tumor diagnosis remains challenging in low-resource clinical environments where expert neuroradiology interpretation, high-end MRI hardware, and invasive biopsy procedures may be limited. Although deep learning has achieved…
Recent radiomic studies have witnessed promising performance of deep learning techniques in learning radiomic features and fusing multimodal imaging data. Most existing deep learning based radiomic studies build predictive models in a…
Automatic pulmonary nodules classification is significant for early diagnosis of lung cancers. Recently, deep learning techniques have enabled remarkable progress in this field. However, these deep models are typically of high computational…
Background and Objective:Computer-aided diagnosis (CAD) systems promote diagnosis effectiveness and alleviate pressure of radiologists. A CAD system for lung cancer diagnosis includes nodule candidate detection and nodule malignancy…
Recent advancements in signal processing and machine learning coupled with developments of electronic medical record keeping in hospitals and the availability of extensive set of medical images through internal/external communication…
While deep learning methods are increasingly being applied to tasks such as computer-aided diagnosis, these models are difficult to interpret, do not incorporate prior domain knowledge, and are often considered as a "black-box." The lack of…
Radiomics with deep learning models have become popular in computer-aided diagnosis and have outperformed human experts on many clinical tasks. Specifically, radiomic models based on artificial intelligence (AI) are using medical data…
Computer-aided diagnosis (CADx) systems have been shown to assist radiologists by providing classifications of all kinds of medical images like Computed tomography (CT) and Magnetic resonance (MR). Currently, convolutional neural networks…
We propose DeepMiner, a framework to discover interpretable representations in deep neural networks and to build explanations for medical predictions. By probing convolutional neural networks (CNNs) trained to classify cancer in mammograms,…
Prostate cancer is one of the most common causes of cancer deaths in men. There is a growing demand for noninvasively and accurately diagnostic methods that facilitate the current standard prostate cancer risk assessment in clinical…
Characterization of lung nodules as benign or malignant is one of the most important tasks in lung cancer diagnosis, staging and treatment planning. While the variation in the appearance of the nodules remains large, there is a need for a…
Incorporation of prior knowledge about organ shape and location is key to improve performance of image analysis approaches. In particular, priors can be useful in cases where images are corrupted and contain artefacts due to limitations in…