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We present Glioma C6, a new open dataset for instance segmentation of glioma C6 cells, designed as both a benchmark and a training resource for deep learning models. The dataset comprises 75 high-resolution phase-contrast microscopy images…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Roman Malashin , Svetlana Pashkevich , Daniil Ilyukhin , Arseniy Volkov , Valeria Yachnaya , Andrey Denisov , Maria Mikhalkova

Mining gene expression profiles has proven valuable for identifying signatures serving as surrogates of cancer phenotypes. However, the similarities of such signatures across different cancer types have not been strong enough to conclude…

Genomics · Quantitative Biology 2020-01-01 Yingcheng Sun , Xiangru Liang , Kenneth Loparo

Lung cancer has been one of the most prevalent disease in recent years. According to the research of this field, more than 200,000 cases are identified each year in the US. Uncontrolled multiplication and growth of the lung cells result in…

Image and Video Processing · Electrical Eng. & Systems 2022-01-04 Hesamoddin Hosseini , Reza Monsefi , Shabnam Shadroo

The distribution and appearance of nuclei are essential markers for the diagnosis and study of cancer. Despite the importance of nuclear morphology, there is a lack of large scale, accurate, publicly accessible nucleus segmentation data. To…

Image and Video Processing · Electrical Eng. & Systems 2020-12-02 Le Hou , Rajarsi Gupta , John S. Van Arnam , Yuwei Zhang , Kaustubh Sivalenka , Dimitris Samaras , Tahsin M. Kurc , Joel H. Saltz

Cancer analysis and prediction is the utmost important research field for well-being of humankind. The Cancer data are analyzed and predicted using machine learning algorithms. Most of the researcher claims the accuracy of the predicted…

Machine Learning · Computer Science 2019-03-19 Ripon Patgiri , Sabuzima Nayak , Tanya Akutota , Bishal Paul

We propose a novel computational framework leveraging hypergraph theory to analyse cancer stem cell markers (CSCMs) across multiple organs. Hypergraphs provide a robust representation of CSCM co-expression patterns, capturing their complex…

Biological Physics · Physics 2025-08-01 David H. Margarit , Gustavo Paccosi , Marcela V. Reale , Lilia M. Romanelli

Predicting drug responses using genetic and transcriptomic features is crucial for enhancing personalized medicine. In this study, we implemented an ensemble of machine learning algorithms to analyze the correlation between genetic and…

Genomics · Quantitative Biology 2025-07-04 Johannes Schlüter , Alexander Schönhuth

Elucidating the genetic basis of human diseases is a central goal of genetics and molecular biology. While traditional linkage analysis and modern high-throughput techniques often provide long lists of tens or hundreds of disease gene…

Quantitative Methods · Quantitative Biology 2011-06-03 Fantine Mordelet , Jean-Philippe Vert

The breakthrough in Deep Learning neural networks has transformed the use of AI and machine learning technologies for the analysis of very large experimental datasets. These datasets are typically generated by large-scale experimental…

Machine Learning · Computer Science 2021-10-26 Jeyan Thiyagalingam , Mallikarjun Shankar , Geoffrey Fox , Tony Hey

Genomics are rapidly transforming medical practice and basic biomedical research, providing insights into disease mechanisms and improving therapeutic strategies, particularly in cancer. The ability to predict the future course of a…

Neural and Evolutionary Computing · Computer Science 2016-09-29 Safoora Yousefi , Congzheng Song , Nelson Nauata , Lee Cooper

The application of deep learning methods, particularly foundation models, in biological research has surged in recent years. These models can be text-based or trained on underlying biological data, especially omics data of various types.…

Artificial Intelligence · Computer Science 2024-12-06 Yoav Kan-Tor , Michael Morris Danziger , Eden Zohar , Matan Ninio , Yishai Shimoni

With recent advancements in the development of artificial intelligence applications using theories and algorithms in machine learning, many accurate models can be created to train and predict on given datasets. With the realization of the…

Machine Learning · Computer Science 2024-03-29 Pei Xi , Lin

Transcriptional profiling on microarrays to obtain gene expressions has been used to facilitate cancer diagnosis. We propose a deep generative machine learning architecture (called DeepCancer) that learn features from unlabeled microarray…

Artificial Intelligence · Computer Science 2016-12-14 Rajendra Rana Bhat , Vivek Viswanath , Xiaolin Li

As much as data science is playing a pivotal role everywhere, healthcare also finds it prominent application. Breast Cancer is the top rated type of cancer amongst women; which took away 627,000 lives alone. This high mortality rate due to…

Machine Learning · Computer Science 2019-02-26 Vivek Kumar , Brojo Kishore Mishra , Manuel Mazzara , Dang N. H. Thanh , Abhishek Verma

Machine learning provides a valuable tool for analyzing high-dimensional functional neuroimaging data, and is proving effective in predicting various neurological conditions, psychiatric disorders, and cognitive patterns. In functional…

Machine Learning · Computer Science 2024-11-25 Anwar Said , Roza G. Bayrak , Tyler Derr , Mudassir Shabbir , Daniel Moyer , Catie Chang , Xenofon Koutsoukos

According to the National Cancer Institute, there were 9.5 million cancer-related deaths in 2018. A challenge in improving treatment is resistance in genetically unstable cells. The purpose of this study is to evaluate unsupervised machine…

Genomics · Quantitative Biology 2021-08-12 Anastasia Dunca , Frederick R. Adler

Cancer is a term that denotes a group of diseases caused by abnormal growth of cells that can spread in different parts of the body. According to the World Health Organization (WHO), cancer is the second major cause of death after…

Machine Learning · Computer Science 2023-01-31 Fadi Alharbi , Aleksandar Vakanski

This research focuses on evaluating and enhancing data readiness for the development of an Artificial Intelligence (AI)-based Clinical Decision Support System (CDSS) in the context of skin cancer treatment. The study, conducted at the Skin…

Artificial Intelligence · Computer Science 2025-03-13 Joscha Grüger , Tobias Geyer , Tobias Brix , Michael Storck , Sonja Leson , Laura Bley , Carsten Weishaupt , Ralph Bergmann , Stephan A. Braun

Collectively, lung cancer, breast cancer and melanoma was diagnosed in over 535,340 people out of which, 209,400 deaths were reported [13]. It is estimated that over 600,000 people will be diagnosed with these forms of cancer in 2015. Most…

Machine Learning · Computer Science 2015-09-29 Mohnish Chakravarti , Tanay Kothari

Tumor volume segmentation on MRI is a challenging and time-consuming process that is performed manually in typical clinical settings. This work presents an approach to automated delineation of head and neck tumors on MRI scans, developed in…

Image and Video Processing · Electrical Eng. & Systems 2025-01-10 Andrei Iantsen