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Spatial patterns arising from the collective behavior of individual agents are present across biological systems. While agent-based models offer a natural framework for uncovering unknown agent (e.g., cell) interactions, these stochastic…

Quantitative Methods · Quantitative Biology 2026-05-19 Yue Liu , Alexandria Volkening

Mathematical models come in many forms across biological applications. In the case of complex, spatial dynamics and pattern formation, stochastic models also face two main challenges: pattern data is largely qualitative, and model…

Cell Behavior · Quantitative Biology 2022-12-26 Electa Cleveland , Angela Zhu , Bjorn Sandstede , Alexandria Volkening

Complex patterns emerge across a wide range of biological systems. While such patterns often exhibit remarkable robustness, variation and irregularity exist at multiple scales and can carry important information about the underlying agent…

Quantitative Methods · Quantitative Biology 2025-09-16 Nour Khoudari , John Nardini , Alexandria Volkening

From flocking birds to schooling fish, organisms interact to form collective dynamics across the natural world. Self-organization is present at smaller scales as well: cells interact and move during development to produce patterns in fish…

Quantitative Methods · Quantitative Biology 2024-07-16 Alexandria Volkening

Collective motion provides a spectacular example of self-organization in Nature. Visual information plays a crucial role among various types of information in determining interactions. Recently, experiments have revealed that organisms such…

Adaptation and Self-Organizing Systems · Physics 2024-07-26 Susumu Ito , Nariya Uchida

Collective motion is one of the most ubiquitous behaviours displayed by social organisms and has led to the development of numerous models. Recent advances in the understanding of sensory system and information processing by animals impel…

Biological Physics · Physics 2016-01-28 Bertrand Collignon , Axel Séguret , José Halloy

Individual computations and social interactions underlying collective behavior in groups of animals are of great ethological, behavioral, and theoretical interest. While complex individual behaviors have successfully been parsed into small…

Neurons and Cognition · Quantitative Biology 2022-06-08 Roy Harpaz , Gašper Tkačik , Elad Schneidman

Collective behaviour in living systems is observed across many scales, from bacteria to insects, to fish shoals. Zebrafish have emerged as a model system amenable to laboratory study. Here we report a three-dimensional study of the…

Statistical Mechanics · Physics 2024-05-16 Yushi Yang , Francesco Turci , Erika Kague , Chrissy L. Hammond , John Russo , C. Patrick Royall

During the last two decades, various models have been proposed for fish collective motion. These models are mainly developed to decipher the biological mechanisms of social interaction between animals. They consider very simple homogeneous…

Neural and Evolutionary Computing · Computer Science 2019-07-23 Leo Cazenille , Nicolas Bredeche , José Halloy

Collective movements are pervasive behaviours among social organisms and have led to the development of many models. However, modelling animal trajectories and social interactions in simple bounded environments remains a challenge.…

Neurons and Cognition · Quantitative Biology 2018-11-28 Leo Cazenille , Nicolas Bredeche , José Halloy

Different cell types aggregate and sort into hierarchical architectures during the formation of animal tissues. The resulting spatial organization depends (in part) on the strength of adhesion of one cell type to itself relative to other…

Quantitative Methods · Quantitative Biology 2023-08-02 Dhananjay Bhaskar , William Y. Zhang , Alexandria Volkening , Björn Sandstede , Ian Y. Wong

Self-organisation of individuals within large collectives occurs throughout biology. Mathematical models can help elucidate the individual-level mechanisms behind these dynamics, but analytical tractability often comes at the cost of…

As zebrafish develop, black and gold stripes form across their skin due to the interactions of brightly colored pigment cells. These characteristic patterns emerge on the growing fish body, as well as on the anal and caudal fins. While…

In this work, we present a computational framework for exploring and analyzing the macroscopic dynamics of complex agent-based network models by integrating Topological Data Analysis with the Equation-Free Method. To demonstrate the…

Dynamical Systems · Mathematics 2026-02-17 Konstantinos Spiliotis , Ole Sönnerborn , Haralampos Hatzikirou , Nikos I. Kavallaris

The real world is awash with multi-agent problems that require collective action by self-interested agents, from the routing of packets across a computer network to the management of irrigation systems. Such systems have local incentives…

Multiagent Systems · Computer Science 2021-02-16 Michiel A. Bakker , Richard Everett , Laura Weidinger , Iason Gabriel , William S. Isaac , Joel Z. Leibo , Edward Hughes

This chapter provides a comprehensive overview of controlling collective behavior in complex systems comprising large ensembles of interacting dynamical agents. Building upon traditional control theory's foundation in individual systems, we…

Systems and Control · Electrical Eng. & Systems 2025-07-01 Marco Coraggio , Davide Salzano , Mario di Bernardo

We use topological data analysis and machine learning to study a seminal model of collective motion in biology [D'Orsogna et al., Phys. Rev. Lett. 96 (2006)]. This model describes agents interacting nonlinearly via attractive-repulsive…

Von Neuman's work on universal machines and the hardware development have allowed the simulation of dynamical systems through a large set of interacting agents. This is a bottom-up approach which tries to derive global properties of a…

Graphics · Computer Science 2007-05-23 Gilson A. Giraldi , Luis C. da Costa , Adilson V. Xavier , Paulo S. Rodrigues

Agent-based modeling is a powerful simulation technique to understand the collective behavior and microscopic interaction in complex financial systems. Recently, the concept for determining the key parameters of the agent-based models from…

Statistical Finance · Quantitative Finance 2017-03-21 T. T. Chen , B. Zheng , Y. Li , X. F. Jiang

Spatial relationships in multi-species data can indicate and affect system outcomes and behaviors, ranging from disease progression in cancer to coral reef resilience in ecology; therefore, quantifying these relationships is an important…

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