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Growing uncertainty from renewable energy integration and distributed energy resources motivate the need for advanced tools to quantify the effect of uncertainty and assess the risks it poses to secure system operation. Polynomial chaos…

Optimization and Control · Mathematics 2019-10-16 David Métivier , Marc Vuffray , Sidhant Misra

In this paper, we develop a stochastic Asymptotic-Preserving (sAP) scheme for the kinetic chemotaxis system with random inputs, which will converge to the modified Keller-Segel model with random inputs in the diffusive regime. Based on the…

Numerical Analysis · Mathematics 2017-10-17 Shi Jin , Hanqing Lu , Lorenzo Pareschi

The processes, resulting in the transcription of RNA, are intrinsically noisy. It was observed experimentally that the synthesis of mRNA molecules is driven by short, burst-like, events. An accurate prediction of the protein level often…

Populations and Evolution · Quantitative Biology 2009-10-14 Vlad Elgart

Gene expression is a central process to any form of life. It involves multiple temporal and functional scales that extend from specific protein-DNA interactions to the coordinated regulation of multiple genes in response to intracellular…

Molecular Networks · Quantitative Biology 2013-07-11 Jose M. G. Vilar , Leonor Saiz

In this paper, a physics-oriented stochastic kinetic scheme will be developed that includes random inputs from both flow and electromagnetic fields via a hybridization of stochastic Galerkin and collocation methods. Based on the BGK-type…

Computational Physics · Physics 2021-03-17 Tianbai Xiao , Martin Frank

We study a multigrid method for solving large linear systems of equations with tensor product structure. Such systems are obtained from stochastic finite element discretization of stochastic partial differential equations such as the…

Numerical Analysis · Mathematics 2017-04-11 Howard C. Elman , Tengfei Su

Neutron noise analysis is a predominant technique for fissile matter identification with passive methods. Quantifying the uncertainties associated with the estimated nuclear parameters is crucial for decision-making. A conservative…

Applications · Statistics 2024-10-03 Paul Lartaud , Philippe Humbert , Josselin Garnier

Molecular signals are abundant in engineering and biological contexts, and undergo stochastic propagation in fluid dynamic channels. The received signal is sensitive to a variety of input and channel parameter variations. Currently we do…

Computational Physics · Physics 2019-02-04 Mahmoud Abbaszadeh , Giannis Moutsinas , Peter J. Thomas , Weisi Guo

We propose, and illustrate via a neural network example, two different approaches to coarse-graining large heterogeneous networks. Both approaches are inspired from, and use tools developed in, methods for uncertainty quantification in…

Adaptation and Self-Organizing Systems · Physics 2016-11-03 Minseok Choi , Tom Bertalan , Carlo R. Laing , Ioannis G. Kevrekidis

We study the Vlasov-Poisson-Fokker-Planck system with uncertainty and multiple scales. Here the uncertainty, modeled by random variables, enters the solution through initial data, while the multiple scales lead the system to its high-field…

Analysis of PDEs · Mathematics 2017-10-18 Shi Jin , Yuhua Zhu

Identifying and quantifying $\gamma$-emitting radionuclides, considering spectral deformation from $\gamma$-interactions in radioactive source surroundings, present a significant challenge in $\gamma$-ray spectrometry. In that context, a…

Data Analysis, Statistics and Probability · Physics 2026-04-23 Dinh Triem Phan , Jérôme Bobin , Cheick Thiam , Christophe Bobin

Background: The availability of high throughput methods for measurement of mRNA concentrations makes the reliability of conclusions drawn from the data and global quality control of samples and hybridization important issues. We address…

Quantitative Methods · Quantitative Biology 2007-05-23 S. Bilke , T. Breslin , M. Sigvardsson

One of the focus areas of modern scientific research is to reveal mysteries related to genes and their interactions. The dynamic interactions between genes can be encoded into a gene regulatory network (GRN), which can be used to gain…

Optimization and Control · Mathematics 2020-07-16 Atte Aalto , Lauri Viitasaari , Pauliina Ilmonen , Laurent Mombaerts , Jorge Goncalves

In two and three dimension we analyze discontinuous Galerkin methods for the acoustic problem. The acoustic fluid that we consider on this paper is inviscid, leading to a linear eigenvalue problem. The acoustic problem is written, in first…

Numerical Analysis · Mathematics 2022-12-09 Felipe Lepe , David Mora , Jesus Vellojin

In the last years, tens of thousands gene expression profiles for cells of several organisms have been monitored. Gene expression is a complex transcriptional process where mRNA molecules are translated into proteins, which control most of…

Biomolecules · Quantitative Biology 2009-11-11 T. Ochiai , J. C. Nacher , T. Akutsu

Generalized Polynomial Chaos (gPC) theory has been widely used for representing parametric uncertainty in a system, thanks to its ability to propagate uncertainty evolution. In an optimal control context, gPC can be combined with several…

Optimization and Control · Mathematics 2021-10-05 Yuichiro Aoyama , Augustinos D. Saravanos , Evangelos A. Theodorou

Biochemical reaction networks are subjected to large fluctuations attributable to small molecule numbers, yet underlie reliable biological functions. Most theoretical approaches describe them as purely deterministic or stochastic dynamical…

Molecular Networks · Quantitative Biology 2013-06-11 Jingkui Wang , Marc Lefranc , Quentin Thommen

We propose a computational approach to modeling the collective dynamics of populations of coupled heterogeneous biological oscillators. In contrast to Monte Carlo simulation, this approach utilizes generalized Polynomial Chaos (gPC) to…

Quantitative Methods · Quantitative Biology 2007-05-23 Katherine A. Bold , Yu Zou , Ioannis G. Kevrekidis , Michael A. Henson

We introduce a framework for the control of discrete-time switched stochastic systems with uncertain distributions. In particular, we consider stochastic dynamics with additive noise whose distribution lies in an ambiguity set of…

Systems and Control · Electrical Eng. & Systems 2024-05-21 Ibon Gracia , Dimitris Boskos , Morteza Lahijanian , Luca Laurenti , Manuel Mazo

We present a novel approach for solving the shallow water equations using a discontinuous Galerkin spectral element method. The method we propose has three main features. First, it enjoys a discrete well-balanced property, in a spirit…

Numerical Analysis · Mathematics 2023-09-15 Yogiraj Mantri , Philipp Öffner , Mario Ricchiuto