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We consider a class of elasticity equations in ${\mathbb R}^d$ whose elastic moduli depend on $n$ separated microscopic scales, are random and expressed as a linear expansion of a countable sequence of random variables which are…

Analysis of PDEs · Mathematics 2016-06-29 Viet Ha Hoang , Thanh Chung Nguyen , Bingxing Xia

In this paper, we study uncertainty quantification (UQ) in forward problems. Our objective is to construct accurate and robust surrogate models by incorporating the seventh-order central weighted essentially non-oscillatory (CWENO7) scheme…

Numerical Analysis · Mathematics 2025-11-04 Alina Chertock , Arsen S. Iskhakov , Alexander Kurganov

Understanding the complex and stochastic nature of Gene Regulatory Networks (GRNs) remains a central challenge in systems biology. Existing modeling paradigms often struggle to effectively capture the intricate, multi-factor regulatory…

Molecular Networks · Quantitative Biology 2025-08-20 Yiyang Jia , Zheng Wei , Zheng Yang , Guohong Peng

This paper considers a class of uncertain linear quantum systems subject to uncertain perturbations in the system Hamiltonian. We present a method to design a coherent robust H-infinity controller so that the closed loop system is robustly…

Systems and Control · Computer Science 2015-09-10 Chengdi Xiang , Ian R. Petersen , Daoyi Dong

We demonstrate that final-state uncertainty is ubiquitous in multistable systems of coupled neuronal maps, meaning that predicting whether one such system will eventually be chaotic or nonchaotic is often nearly impossible. We propose a…

Neurons and Cognition · Quantitative Biology 2025-07-22 Brandon B. Le , Bennett Lamb , Luke Benfer , Sriharsha Sambangi , Nisal Geemal Vismith , Akshaj Jagarapu

Neuronal systems often preserve their characteristic functions and signalling patterns, also referred to as regimes, despite parametric uncertainties and variations. For neural models having uncertain parameters with a known probability…

Neurons and Cognition · Quantitative Biology 2026-02-19 Uros Sutulovic , Daniele Proverbio , Rami Katz , Giulia Giordano

We present a novel approach to determine the evolution of level sets under uncertainties in the velocity fields. This leads to a stochastic description of the level sets. To compute the quantiles of random level sets, we use the stochastic…

Probability · Mathematics 2023-05-10 Markus Bambach , Stephan Gerster , Michael Herty , Aleksey Sikstel

A general class of stochastic gene expression models with self regulation is considered. One or more genes randomly switch between regulatory states, each having a different mRNA transcription rate. The gene or genes are self regulating…

Molecular Networks · Quantitative Biology 2014-12-30 Jay Newby

A discontinuous Galerkin pressure correction numerical method for solving the incompressible Navier-Stokes equations is formulated and analyzed. We prove unconditional stability of the propose scheme. Convergence of the discrete velocity is…

Numerical Analysis · Mathematics 2021-09-24 Rami Masri , Chen Liu , Beatrice Riviere

Wave propagation problems for heterogeneous media are known to have many applications in physics and engineering. Recently, there has been an increasing interest in stochastic effects due to the uncertainty, which may arise from impurities…

Numerical Analysis · Mathematics 2019-02-20 Ching-Shan Chou , Yukun Li , Dongbin Xiu

This brief paper proposes an uncertainty quantification method for the periodic steady-state (PSS) analysis with both Gaussian and non-Gaussian variations. Our stochastic testing formulation for the PSS problem provides superior efficiency…

Computational Engineering, Finance, and Science · Computer Science 2016-11-18 Zheng Zhang , Tarek A. El-Moselhy , Paolo Maffezzoni , Ibrahim , M. Elfadel , Luca Daniel

Dynamical systems in biology are complex, and one often does not have comprehensive knowledge about the interactions involved. Chemical reaction network (CRN) inference aims to identify, from observing species concentrations over time, the…

Methodology · Statistics 2026-04-15 Yong See Foo , Adriana Zanca , Jennifer A. Flegg , Ivo Siekmann

Exploiting the information provided by the molecular noise of a biological process has proven to be valuable in extracting knowledge about the underlying kinetic parameters and sources of variability from single cell measurements. However,…

Quantitative Methods · Quantitative Biology 2013-08-30 Jakob Ruess , Andreas Milias-Argeitis , John Lygeros

Mathematical modeling at the level of the full cardiovascular system requires the numerical approximation of solutions to a one-dimensional nonlinear hyperbolic system describing flow in a single vessel. This model is often simulated by…

Computational Physics · Physics 2015-04-22 Sebastian Acosta , Charles Puelz , Beatrice Riviere , Daniel J. Penny , Craig G. Rusin

The goal of this paper is to outline a scenario of emerging stochasticity in high-dimensional highly nonlinear systems, such as genetic regulatory networks (GRN). We focus attention on the fact that in such systems confluence of all the…

Molecular Networks · Quantitative Biology 2007-09-19 Simon Rosenfeld

Gene expression analysis aims at identifying the genes able to accurately predict biological parameters like, for example, disease subtyping or progression. While accurate prediction can be achieved by means of many different techniques,…

Methodology · Statistics 2008-09-11 Christine De Mol , Sofia Mosci , Magali Traskine , Alessandro Verri

We investigate numerical behaviour of a convection diffusion equation with random coefficients by approximating statistical moments of the solution. Stochastic Galerkin approach, turning the original stochastic problem to a system of…

Numerical Analysis · Mathematics 2021-10-19 Pelin Çiloğlu , Hamdullah Yücel

A time discretization method is called strongly stable, if the norm of its numerical solution is nonincreasing. It is known that, even for linear semi-negative problems, many explicit Runge--Kutta (RK) methods fail to preserve this…

Numerical Analysis · Mathematics 2019-12-30 Zheng Sun , Chi-Wang Shu

Benchmark rankings are routinely used to justify scientific claims about method quality in gene regulatory network (GRN) inference, yet the stability of these rankings under plausible evaluation protocol choices is rarely examined. We…

Molecular Networks · Quantitative Biology 2026-03-05 Ihor Kendiukhov

The post-Moore era casts a shadow of uncertainty on many aspects of computer system design. Managing that uncertainty requires new algorithmic tools to make quantitative assessments. While prior uncertainty quantification methods, such as…

Signal Processing · Electrical Eng. & Systems 2019-10-22 Zichang He , Weilong Cui , Chunfeng Cui , Timothy Sherwood , Zheng Zhang
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