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Recent development of quantitative myocardial blood flow (MBF) mapping allows direct evaluation of absolute myocardial perfusion, by computing pixel-wise flow maps. Clinical studies suggest quantitative evaluation would be more desirable…

Quantitative Methods · Quantitative Biology 2020-06-01 Hui Xue , Rhodri Davies , Louis AE Brown , Kristopher D Knott , Tushar Kotecha , Marianna Fontana , Sven Plein , James C Moon , Peter Kellman

Perfusion imaging is crucial in acute ischemic stroke for quantifying the salvageable penumbra and irreversibly damaged core lesions. As such, it helps clinicians to decide on the optimal reperfusion treatment. In perfusion CT imaging,…

Image and Video Processing · Electrical Eng. & Systems 2022-04-27 Ezequiel de la Rosa , Diana M. Sima , Bjoern Menze , Jan S. Kirschke , David Robben

Objective: This paper proposes a novel approach for automatic left ventricle (LV) quantification using convolutional neural networks (CNN). Methods: The general framework consists of one CNN for detecting the LV, and another for tissue…

Computer Vision and Pattern Recognition · Computer Science 2018-12-17 Ariel H. Curiale , Flavio D. Colavecchia , German Mato

Dynamic positron emission tomography (PET) imaging combined with radiotracer kinetic modeling is a powerful technique for visualizing biological processes in the brain, offering valuable insights into brain functions and neurological…

Image and Video Processing · Electrical Eng. & Systems 2025-11-26 Junyu Chen , Zirui Jiang , Jennifer M. Coughlin , Ian Cheong , Kelly A. Mills , Martin G. Pomper , Yong Du

Background. With the rise of highly portable, wireless, and low-cost ultrasound devices and automatic ultrasound acquisition techniques, an automated interpretation method requiring only a limited set of views as input could make…

Image and Video Processing · Electrical Eng. & Systems 2025-04-29 Li-Hsin Cheng , Pablo B. J. Bosch , Rutger F. H. Hofman , Timo B. Brakenhoff , Eline F. Bruggemans , Rob J. van der Geest , Eduard R. Holman

Perfusion imaging is the current gold standard for acute ischemic stroke analysis. It allows quantification of the salvageable and non-salvageable tissue regions (penumbra and core areas respectively). In clinical settings, the singular…

Image and Video Processing · Electrical Eng. & Systems 2021-04-01 Ezequiel de la Rosa , David Robben , Diana M. Sima , Jan S. Kirschke , Bjoern Menze

Dynamic positron emission tomography (PET) and kinetic modeling are pivotal in advancing tracer development research in small animal studies. Accurate kinetic modeling requires precise input function estimation, traditionally achieved via…

Automatic segmentation of left ventricle (LV) myocardium in cardiac short-axis cine MR images acquired on subjects with myocardial infarction is a challenging task, mainly because of the various types of image inhomogeneity caused by the…

Computer Vision and Pattern Recognition · Computer Science 2018-11-16 Dongqing Zhang , Ilknur Icke , Belma Dogdas , Sarayu Parimal , Smita Sampath , Joseph Forbes , Ansuman Bagchi , Chih-Liang Chin , Antong Chen

Myocardial characterization is essential for patients with myocardial infarction and other myocardial diseases, and the assessment is often performed using cardiac magnetic resonance (CMR) sequences. In this study, we propose a fully…

Image and Video Processing · Electrical Eng. & Systems 2020-08-19 Xiaoran Zhang , Michelle Noga , Kumaradevan Punithakumar

Purpose: Identifying intravenous (IV) contrast use within CT scans is a key component of data curation for model development and testing. Currently, IV contrast is poorly documented in imaging metadata and necessitates manual correction and…

Image and Video Processing · Electrical Eng. & Systems 2021-10-22 Zezhong Ye , Jack M. Qian , Ahmed Hosny , Roman Zeleznik , Deborah Plana , Jirapat Likitlersuang , Zhongyi Zhang , Raymond H. Mak , Hugo J. W. L. Aerts , Benjamin H. Kann

The echocardiographic measurement of left ventricular ejection fraction (LVEF) is fundamental to the diagnosis and classification of patients with heart failure (HF). In order to quantify LVEF automatically and accurately, this paper…

Arterial spin labeling (ASL) allows to quantify the cerebral blood flow (CBF) by magnetic labeling of the arterial blood water. ASL is increasingly used in clinical studies due to its noninvasiveness, repeatability and benefits in…

Computer Vision and Pattern Recognition · Computer Science 2018-06-13 Cagdas Ulas , Giles Tetteh , Stephan Kaczmarz , Christine Preibisch , Bjoern H. Menze

Kinetic modeling enables \textit{in vivo} quantification of tracer uptake and glucose metabolism in [${}^{18}$F]Fluorodeoxyglucose ([${}^{18}$F]FDG) dynamic positron emission tomography (dPET) imaging of mice. However, kinetic modeling…

Quantitative Methods · Quantitative Biology 2025-10-27 Christian Salomonsen , Kristoffer K. Wickstrøm , Samuel Kuttner , Elisabeth Wetzer

We propose a fully automated algorithm based on a deep learning framework enabling screening of a coronary computed tomography angiography (CCTA) examination for confident detection of the presence or absence of coronary artery…

Image and Video Processing · Electrical Eng. & Systems 2020-06-09 Sema Candemir , Richard D. White , Mutlu Demirer , Vikash Gupta , Matthew T. Bigelow , Luciano M. Prevedello , Barbaros S. Erdal

In patients with coronary artery stenoses of intermediate severity, the functional significance needs to be determined. Fractional flow reserve (FFR) measurement, performed during invasive coronary angiography (ICA), is most often used in…

Computer Vision and Pattern Recognition · Computer Science 2018-08-21 Majd Zreik , Nikolas Lessmann , Robbert W. van Hamersvelt , Jelmer M. Wolterink , Michiel Voskuil , Max A. Viergever , Tim Leiner , Ivana Išgum

Remarkable progress has been made in image recognition, primarily due to the availability of large-scale annotated datasets and the revival of deep CNN. CNNs enable learning data-driven, highly representative, layered hierarchical image…

Computer Vision and Pattern Recognition · Computer Science 2016-02-11 Hoo-Chang Shin , Holger R. Roth , Mingchen Gao , Le Lu , Ziyue Xu , Isabella Nogues , Jianhua Yao , Daniel Mollura , Ronald M. Summers

Cardiac left ventricle (LV) quantification provides a tool for diagnosing cardiac diseases. Automatic calculation of all relevant LV indices from cardiac MR images is an intricate task due to large variations among patients and deformation…

Image and Video Processing · Electrical Eng. & Systems 2020-02-04 Nils Gessert , Alexander Schlaefer

Left ventricular ejection fraction (LVEF) is a key indicator of cardiac function and plays a central role in the diagnosis and management of cardiovascular disease. Echocardiography, as a readily accessible and non-invasive imaging…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Shravan Saranyan , Pramit Saha

Lacunes of presumed vascular origin (lacunes) are associated with an increased risk of stroke, gait impairment, and dementia and are a primary imaging feature of the small vessel disease. Quantification of lacunes may be of great importance…

Invasive coronary angiography (ICA) is the gold standard in Coronary Artery Disease (CAD) imaging. Detection of the end-diastolic frame (EDF) and, in general, cardiac phase detection on each temporal frame of a coronary angiography…

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