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Ultrasound Localization Microscopy (ULM) relies on the injection of microbubbles (MBs) to obtain highly resolved density maps of blood circulation in vivo, with a resolution that can reach 10 {\mu}m ~ {\lambda}/10 in the rodent brain.…

Image acquisition techniques such as micro-computed tomography are nowadays widely available. Quantitative analysis of the resulting 3D image data enables geometric characterization of the micro-structure of materials. Stochastic geometry…

Numerical Analysis · Mathematics 2025-01-28 Anne Jung , Claudia Redenbach , Katja Schladitz , Sarah Staub

Dislocations in a material will, when present in enough numbers, change the speed of propagation of elastic waves. Consequently, two material samples, differing only in dislocation density, will have different elastic constants, a quantity…

Diagnostic imaging plays a critical role in healthcare, serving as a fundamental asset for timely diagnosis, disease staging and management as well as for treatment choice, planning, guidance, and follow-up. Among the diagnostic imaging…

Signal Processing · Electrical Eng. & Systems 2021-09-24 Ruud JG van Sloun , Jong Chul Ye , Yonina C Eldar

Over almost five decades of development and improvement, Magnetic Resonance Imaging (MRI) has become a rich and powerful, non-invasive technique in medical imaging, yet not reaching its physical limits. Technical and physiological…

Metamaterials are constructed such that, for a narrow range of frequencies, the momentum density depends on the local displacement gradient, and the stress depends on the local velocity. In these models the momentum density generally…

Mathematical Physics · Physics 2009-11-13 Graeme W. Milton

In a systematic review, we investigate current applications of ultrasound in locomotion research. Shortcomings in the range of view of ultrasound systems affect the direct validation of musculoskeletal simulations as inverse approaches have…

Quantitative Methods · Quantitative Biology 2020-01-22 Christoph Leitner , Christian Baumgartner , Christian Peham , Markus Tilp

There is a growing mechanics literature concerning the macroscopic properties of mechanism-based mechanical metamaterials. This amounts mathematically to a homogenization problem involving nonlinear elasticity. A key goal is to identify the…

Analysis of PDEs · Mathematics 2025-11-10 Xuenan Li , Robert V. Kohn

Photoacoustic imaging systems offer a platform with high resolution to explore body tissues, food, and artwork. On the other hand, plasmonics constitutes a source of resonant heating and thermal expansion to generate acoustic waves.…

Applied Physics · Physics 2022-08-29 Ricardo Martín Abraham-Ekeroth

Characterizing the elastic properties of soft materials through bulge testing relies on accurate measurement of deformation, which is experimentally challenging. To avoid measuring deformation, we propose a hydrodynamic bulge test for…

Soft Condensed Matter · Physics 2020-03-17 Vishal Anand , Sanjan C. Muchandimath , Ivan C. Christov

3D ultrasound imaging provides more spatial information compared to conventional 2D frames by considering the volumes of data. One of the main bottlenecks of 3D imaging is the long data acquisition time which reduces practicality and can…

Pump-probe microscopy is an emerging nonlinear imaging technique based on high repetition rate lasers and fast intensity modulation. Here we present new methods for pump-probe microscopy that keep the beam intensity constant and instead…

Optics · Physics 2021-04-07 Jun Jiang , David Grass , Yue Zhou , Warren S. Warren , Martin C. Fischer

Ultrasound-matter interactions underpin numerous biomedical and soft-matter applications, yet simulating these phenomena is challenging due to the large separation of viscous and sonic time scales. Continuum methods capture large-scale wave…

Soft Condensed Matter · Physics 2026-02-18 Urban Čoko , Tilen Potisk , Matej Praprotnik

Recent improvements in additive manufacturing and high-throughput material synthesis have enabled the discovery of novel metallic materials for extreme environments. However, high-fidelity testing of advanced mechanical properties such as…

Materials Science · Physics 2025-02-20 C. Bean , M. Calvat , Y. Nie , R. L Black , N. Velisavljevic , D. Anjaria , M. A. Charpagne , J. C. Stinville

Major biological discoveries have been made by interrogating living organisms with light. However, the limited penetration of unscattered photons within biological tissues severely limits the depth range covered by optical methods.…

Dynamic elastography is a widely used, safe, convenient, and cost-effective method to aid in medical diagnosis. It visualizes the wave field propagating through living tissues and quantitatively determines the wave propagation speed from…

Analysis of PDEs · Mathematics 2026-04-15 Yu Jiang , Ching-Lung Lin , Gen Nakamura

The layering approach used in fused filament fabrication (FFF) enables creation of complex designs generated by topology optimization. Defects associated with the layer-by-layer process, introduce considerable random variability to the…

Materials Science · Physics 2024-09-04 Zahra Kazemi , Craig A. Steeves

Breast cancer is the most common invasive cancer in women. Besides the primary B-mode ultrasound screening, sonographers have explored the inclusion of Doppler, strain and shear-wave elasticity imaging to advance the diagnosis. However,…

Image and Video Processing · Electrical Eng. & Systems 2020-08-11 Wang Jian , Miao Juzheng , Yang Xin , Li Rui , Zhou Guangquan , Huang Yuhao , Lin Zehui , Xue Wufeng , Jia Xiaohong , Zhou Jianqiao , Huang Ruobing , Ni Dong

Extracting reliable and quantitative microstructure information of living tissue by non-invasive imaging is an outstanding challenge for understanding disease mechanisms and allowing early stage diagnosis of pathologies. Magnetic Resonance…

Medical Physics · Physics 2021-07-12 Milena Capiglioni , Analia Zwick , Pablo Jimenez , Gonzalo A. Alvarez

The MechElastic Python package evaluates the mechanical and elastic properties of bulk and 2D materials using the elastic coefficient matrix ($C_{ij}$) obtained from any ab-initio density-functional theory (DFT) code. The current version of…