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Deep learning has been successfully applied to low-dose CT (LDCT) image denoising for reducing potential radiation risk. However, the widely reported supervised LDCT denoising networks require a training set of paired images, which is…

Machine Learning · Computer Science 2023-02-09 Yuhui Ruan , Qiao Yuan , Chuang Niu , Chen Li , Yudong Yao , Ge Wang , Yueyang Teng

The extensive use of medical CT has raised a public concern over the radiation dose to the patient. Reducing the radiation dose leads to increased CT image noise and artifacts, which can adversely affect not only the radiologists judgement…

Image and Video Processing · Electrical Eng. & Systems 2021-07-13 Jiajin Zhang , Hanqing Chao , Xuanang Xu , Chuang Niu , Ge Wang , Pingkun Yan

Background: Dual-energy CT (DECT) and material decomposition play vital roles in quantitative medical imaging. However, the decomposition process may suffer from significant noise amplification, leading to severely degraded image…

Mask-based lensless imagers are smaller and lighter than traditional lensed cameras. In these imagers, the sensor does not directly record an image of the scene; rather, a computational algorithm reconstructs it. Typically, mask-based…

Image and Video Processing · Electrical Eng. & Systems 2019-09-27 Kristina Monakhova , Joshua Yurtsever , Grace Kuo , Nick Antipa , Kyrollos Yanny , Laura Waller

We present a method that lowers the dose required for a ptychographic reconstruction by adaptively scanning the specimen, thereby providing the required spatial information redundancy in the regions of highest importance. The proposed…

Computational Physics · Physics 2022-03-30 Marcel Schloz , Johannes Müller , Thomas C. Pekin , Wouter Van den Broek , Christoph T. Koch

We propose a model-based deep learning architecture for the reconstruction of highly accelerated diffusion magnetic resonance imaging (MRI) that enables high resolution imaging. The proposed reconstruction jointly recovers all the diffusion…

Image and Video Processing · Electrical Eng. & Systems 2020-01-24 Merry P. Mani , Hemant K. Aggarwal , Sanjay Ghosh , Mathews Jacob

Diffusion models (DMs) have recently been introduced as a regularizing prior for PET image reconstruction, integrating DMs trained on high-quality PET images with unsupervised schemes that condition on measured data. While these approaches…

Medical Physics · Physics 2026-03-18 George Webber , Alexander Hammers , Andrew P King , Andrew J Reader

X-ray computed tomographic infrastructures are medical imaging modalities that rely on the acquisition of rays crossing examined objects while measuring their intensity decrease. Physical measurements are post-processed by mathematical…

Image and Video Processing · Electrical Eng. & Systems 2022-01-25 Attila Juhos

Recently, compressed sensing (CS) computed tomography (CT) using sparse projection views has been extensively investigated to reduce the potential risk of radiation to patient. However, due to the insufficient number of projection views, an…

Computer Vision and Pattern Recognition · Computer Science 2016-11-28 Yo Seob Han , Jaejun Yoo , Jong Chul Ye

Obtaining accurate and reliable images from low-dose computed tomography (CT) is challenging. Regression convolutional neural network (CNN) models that are learned from training data are increasingly gaining attention in low-dose CT…

Image and Video Processing · Electrical Eng. & Systems 2019-08-06 Il Yong Chun , Xuehang Zheng , Yong Long , Jeffrey A. Fessler

Deep learning based computed tomography (CT) reconstruction has demonstrated outstanding performance on simulated 2D low-dose CT data. This applies in particular to domain adapted neural networks, which incorporate a handcrafted physics…

Image and Video Processing · Electrical Eng. & Systems 2023-11-30 Jevgenija Rudzusika , Buda Bajić , Thomas Koehler , Ozan Öktem

Multi-energy computed tomography (CT) with photon counting detectors (PCDs) enables spectral imaging as PCDs can assign the incoming photons to specific energy channels. However, PCDs with many spectral channels drastically increase the…

Image and Video Processing · Electrical Eng. & Systems 2022-11-03 Satu I. Inkinen , Mikael A. K. Brix , Miika T. Nieminen , Simon Arridge , Andreas Hauptmann

In PET, the amount of relative (signal-dependent) noise present in different body regions can be significantly different and is inherently related to the number of counts present in that region. The number of counts in a region depends, in…

Image and Video Processing · Electrical Eng. & Systems 2022-12-20 Ye Li , Jianan Cui , Junyu Chen , Guodong Zeng , Scott Wollenweber , Floris Jansen , Se-In Jang , Kyungsang Kim , Kuang Gong , Quanzheng Li

The Computed Tomography (CT) for diagnosis of lesions in human internal organs is one of the most fundamental topics in medical imaging. Low-dose CT, which offers reduced radiation exposure, is preferred over standard-dose CT, and therefore…

Image and Video Processing · Electrical Eng. & Systems 2023-09-26 Wenjie Liu

In clinical CT, the x-ray source emits polychromatic x-rays, which are detected in the current-integrating mode. This physical process is accurately described by an energy-dependent non-linear integral model on the basis of the Beer-Lambert…

Medical Physics · Physics 2018-01-11 Wenxiang Cong , Ge Wang

The development of computed tomography (CT) image reconstruction methods that significantly reduce patient radiation exposure while maintaining high image quality is an important area of research in low-dose CT (LDCT) imaging. We propose a…

Machine Learning · Statistics 2019-06-14 Xuehang Zheng , Saiprasad Ravishankar , Yong Long , Jeffrey A. Fessler

Computed tomography is widely used as an imaging tool to visualize three-dimensional structures with expressive bone-soft tissue contrast. However, CT resolution and radiation dose are tightly entangled, highlighting the importance of…

This work is concerned with applying iterative image reconstruction, based on constrained total-variation minimization, to low-intensity X-ray CT systems that have a high sampling rate. Such systems pose a challenge for iterative image…

Medical Physics · Physics 2016-11-17 Emil Y. Sidky , Rick Chartrand , Yuval Duchin , Christer Ullberg , Xiaochuan Pan

Low-dose computed tomography (CT) has attracted a major attention in the medical imaging field, since CT-associated x-ray radiation carries health risks for patients. The reduction of CT radiation dose, however, compromises the…

Computer Vision and Pattern Recognition · Computer Science 2019-07-16 Hongming Shan , Yi Zhang , Qingsong Yang , Uwe Kruger , Mannudeep K. Kalra , Ling Sun , Wenxiang Cong , Ge Wang

Recently, deep learning-based compressed sensing (CS) has achieved great success in reducing the sampling and computational cost of sensing systems and improving the reconstruction quality. These approaches, however, largely overlook the…

Computer Vision and Pattern Recognition · Computer Science 2023-04-25 Yu Zhou , Yu Chen , Xiao Zhang , Pan Lai , Lei Huang , Jianmin Jiang