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Phase-separated biomolecular condensates exhibit a wide range of dynamical properties, which depend on the sequences of the constituent proteins and RNAs. However, it is unclear to what extent condensate dynamics can be tuned without also…

Biomolecules · Quantitative Biology 2024-07-31 Yaxin An , Michael A. Webb , William M. Jacobs

The equilibrium phase behaviour of hard spheres with size polydispersity is studied theoretically. We solve numerically the exact phase equilibrium equations that result from accurate free energy expressions for the fluid and solid phases,…

Soft Condensed Matter · Physics 2007-05-23 M. Fasolo , P. Sollich

Microphase separated structure consisting of the periodic alternation of the layers of stretched homopolymer chains surrounded by perpendicularly oriented oligomeric tails is studied for both, strongly bonded (ionic) systems and weakly…

Statistical Mechanics · Physics 2007-05-23 A. Olemskoi , I. Krakovsky , A. Savelyev

Four scenarios have been proposed for the low--temperature phase behavior of liquid water, each predicting different thermodynamics. The physical mechanism which leads to each is debated. Moreover, it is still unclear which of the scenarios…

Soft Condensed Matter · Physics 2009-08-27 Kevin Stokely , Marco G. Mazza , H. Eugene Stanley , Giancarlo Franzese

The phase-field-crystal model for liquid crystals is solved numerically in two spatial dimensions. This model is formulated with three position-dependent order parameters, namely the reduced translational density, the local nematic order…

Soft Condensed Matter · Physics 2014-01-28 Cristian Vasile Achim , Raphael Wittkowski , Hartmut Löwen

We present a dynamical model of lipoprotein metabolism derived by combining a cascading process in the blood stream and cellular level regulatory dynamics. We analyse the existence and stability of equilibria and show that this…

Quantitative Methods · Quantitative Biology 2007-05-23 Elias August , Kim H. Parker , Mauricio Barahona

Complex coacervation, known as the liquid-liquid phase separation of solutions with oppositely charged polyelectrolytes, has attracted substantial interest in recent years. We study the effect of the charge regulation (CR) mechanism on the…

Soft Condensed Matter · Physics 2021-07-23 Bin Zheng , Yael Avni , David Andelman , Rudolf Podgornik

We investigate the phase behavior of a single-component system in 3 dimensions with spherically-symmetric, pairwise-additive, soft-core interactions with an attractive well at a long distance, a repulsive soft-core shoulder at an…

Soft Condensed Matter · Physics 2009-11-07 G. Franzese , G. Malescio , A. Skibinsky , S. V. Buldyrev , H. E. Stanley

Motility-induced phase separation (MIPS) is a well-studied nonequilibrium collective phenomenon observed in active particles. Recently, there has been growing interest in how coupling the self-propulsion of active particles to chemical…

Soft Condensed Matter · Physics 2025-07-14 Euijoon Kwon , Yongjae Oh , Yongjoo Baek

We use a continuum model to examine the effect of activity on a phase separating mixture of an extensile active nematic and a passive fluid. We highlight the distinct role of previously considered interfacial active stresses and bulk active…

Soft Condensed Matter · Physics 2022-12-26 Fernando Caballero , M. Cristina Marchetti

We study the phase equilibrium between liquid water and ice Ih modeled by the TIP4P/Ice interatomic potential using enhanced sampling molecular dynamics simulations. Our approach is based on the calculation of ice Ih-liquid free energy…

Statistical Mechanics · Physics 2020-06-24 Pablo M. Piaggi , Roberto Car

The separation of substances into different phases is ubiquitous in nature and important scientifically and technologically. This phenomenon may become drastically different if the species involved, whether molecules or supramolecular…

The self-organization of proteins into enriched compartments and the formation of complex patterns are crucial processes for life on the cellular level. Liquid-liquid phase separation is one mechanism for forming such enriched compartments.…

Soft Condensed Matter · Physics 2025-04-07 Antonia Winter , Yuhao Liu , Alexander Ziepke , George Dadunashvili , Erwin Frey

The distinctive characteristics of water, evident in its thermodynamic anomalies, have implications across disciplines from biology to geophysics. Considered a valid hypothesis to rationalize its unique properties, a liquid-liquid phase…

Soft Condensed Matter · Physics 2025-12-08 Maria Grazia Izzo , John Russo , Giorgio Pastore

We study dynamic heterogeneities in a model glass-former whose overlap with a reference configuration is constrained to a fixed value. The system phase-separates into regions of small and large overlap, so that dynamical correlations remain…

Disordered Systems and Neural Networks · Physics 2012-07-19 C. Cammarota , A. Cavagna , I. Giardina , G. Gradenigo , T. S. Grigera , G. Parisi , P. Verrocchio

We study the problem of phase separation in systems with a positive definite order parameter, and in particular, in systems with absorbing states. Owing to the presence of a single minimum in the free energy driving the relaxation kinetics,…

Condensed Matter · Physics 2009-10-31 M. A. Munoz , U. Marini Bettolo Marconi , R. Cafiero

The phase behaviour and dynamics of molecular ionic liquids are studied using primitive models and extensive computer simulations. The models account for size disparity between cation and anion, charge location on the cation, and…

Soft Condensed Matter · Physics 2012-02-23 G. C. Ganzenmüller , P. J. Camp

Phase separation, i.e., the coexistence of two different phases, is observed in many systems away from the coexistence curve of a first-order transition, leading to a stable heterogeneous phase or region. Examples include various quantum…

Strongly Correlated Electrons · Physics 2016-04-27 T. R. Kirkpatrick , D. Belitz

Conventional phase segregation is controlled by a positive interfacial tension, which implies that the system relaxes towards a state in which the interfacial area (or length) is minimized, typically manifesting as a single droplet that…

Soft Condensed Matter · Physics 2025-09-24 Kathrin Hertäg , Joshua F. Robinson , Thomas Speck

In this study we use non-equilibrium thermodynamics to systematically derive a phase-field model of a polyelectrolyte gel coupled to a hydrodynamic model for a salt solution surrounding the gel. The governing equations for the gel account…

Soft Condensed Matter · Physics 2022-03-02 Giulia L. Celora , Matthew G. Hennessy , Andreas Münch , Barbara Wagner , Sarah L. Waters