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Nanoscale and microscale confinement of biopolymers naturally occurs in cells and has been recently achieved in artificial structures designed for nanotechnological applications. Here, we present an extensive theoretical investigation of…

Soft Condensed Matter · Physics 2007-06-13 Frederik Wagner , Gianluca Lattanzi , Erwin Frey

Many variants of RNA, DNA, and even proteins can be considered semiflexible polymers, where bending stiffness, as a type of energetic penalty, competes with attractive van der Waals forces in structure formation processes. Here, we…

Soft Condensed Matter · Physics 2023-06-07 Dilimulati Aierken , Michael Bachmann

Molecular dynamics simulation of a generic polymer model is applied to study melts of polymers with different types of intrinsic stiffness. Important static observables of the single chain such as gyration radius or persistence length are…

Soft Condensed Matter · Physics 2017-09-13 Roland Faller , Alexander Kolb , Florian Müller-Plathe

We analyse the nature of the confinement of an infinitely long (and finite) linear semiflexible homo-polymer chain confined in between two geometrical constraints (A&B) under good solvent condition in two dimensions. The constraints are…

Soft Condensed Matter · Physics 2017-10-16 Pramod Kumar Mishra

We make use of the previously developed formalism for a monomer ensemble and include angular dependence of the segments of the polymer chains thus described. In particular we show how to deal with stiffness when the polymer chain is…

Soft Condensed Matter · Physics 2015-06-24 K. K. Muller-Nedebock , H. L. Frisch , J. K. Percus

We use Wang-Landau and replica exchange techniques to study the effect of an increasing stiffness on the formation of secondary structures in protein-like systems. Two possible models are considered. In both models, a polymer chain is…

Soft Condensed Matter · Physics 2016-09-21 Tatjana Skrbic , Trinh X. Hoang , Achille Giacometti

The shape of a polymer plays an important role in determining its interactions with other molecules and with the environment, and is in turn affected by both of them. As a consequence, in the literature the shape properties of a chain in…

Soft Condensed Matter · Physics 2017-07-26 Alberto S. Sassi , Salvatore Assenza , Paolo De Los Rios

Semiflexible polymers in poor solvents exhibit a rich variety of collapsed morphologies, including globules, toroids, and rodlike bundles, arising from the competition between attractive interactions and chain stiffness. Computer…

Statistical Mechanics · Physics 2026-01-22 Biman Bagchi

The paper develops the stiffness relationship between the movements and forces among a system of discrete interacting grains. The approach is similar to that used in structural analysis, but the stiffness matrix of granular material is…

Soft Condensed Matter · Physics 2019-05-01 Matthew R. Kuhn , Florent Prunier , Ali Daouadji

Active polymers possess numerous unique properties that are quite different from those observed in the system of small active molecule due to the intricate interplay between their activity and topological constraints. This study focuses on…

Soft Condensed Matter · Physics 2024-07-09 Jing Li , Bokai Zhang , Zhi-Yong Wang

A formula is derived for stiffness of a polymer chain in terms of the distribution function of end-to-end vectors. This relationship is applied to calculate the stiffness of Gaussian chains (neutral and carrying electric charges at the…

Statistical Mechanics · Physics 2007-05-23 A. D. Drozdov

Synthetic copolymers and biopolymers, such as polypeptides and double-stranded DNA, often exhibit strong variations in bending stiffness along their contour, which can significantly impact conformational behavior at larger scales. To…

Soft Condensed Matter · Physics 2025-11-04 Yannick Witzky , Friederike Schmid , Arash Nikoubashman

We present the results of analytic calculations and numerical simulations of the behaviour of a new class of chain molecules which we call thick polymers. The concept of the thickness of such a polymer, viewed as a tube, is encapsulated by…

Soft Condensed Matter · Physics 2015-06-25 D. Marenduzzo , A. Flammini , A. Trovato , J. R. Banavar , A. Maritan

Chain-like macromolecules in solution, whether biological or synthetic, transform from an extended conformation to a compact one when temperature or other system parameters change. This collapse transition is relevant in various phenomena,…

Soft Condensed Matter · Physics 2026-05-18 Yanyan Zhu , Haim Diamant , David Andelman

Polymeric single-chain nanoparticles (SCNPs) are soft nano-objects synthesized by purely intramolecular cross-linking of single polymer chains. By means of computer simulations, we investigate the conformational properties of SCNPs as a…

Soft Condensed Matter · Physics 2018-01-17 Angel J. Moreno , Petra Bacova , Federica Lo Verso , Arantxa Arbe , Juan Colmenero , Jose A. Pomposo

We have studied the thermodynamics of isolated homopolymer chains of varying stiffness using a lattice model. A complex phase behaviour is found; phases include chain-folded `crystalline' structures, the disordered globule and the coil. It…

Soft Condensed Matter · Physics 2008-02-03 Jonathan Doye , Richard Sear , Daan Frenkel

We constrast the dynamics in model unentangled polymer melts of chains of three different stiffnesses: flexible, intermediate, and rodlike. Flexible and rodlike chains, which readily solidify into close-packed crystals (respectively with…

Soft Condensed Matter · Physics 2016-11-23 Hong T. Nguyen , Robert S. Hoy

Chain molecules play a key role in the polymer field and in living cells. Our focus is on a new homopolymer model of a linear chain molecule subject to an attractive self-interaction promoting compactness. We analyze the model using simple…

Statistical Mechanics · Physics 2021-07-14 Tatjana Škrbić , Trinh Xuan Hoang , Achille Giacometti , Amos Maritan , Jayanth R. Banavar

Using a combination of the replica-exchange Monte Carlo algorithm and the multicanonical method, we investigate the influence of bending stiffness on the conformational phases of a bead-stick homopolymer model and present the pseudo-phase…

Soft Condensed Matter · Physics 2016-03-30 Martin Marenz , Wolfhard Janke

Using Langevin dynamics complemented by Wang-Landau Monte Carlo simulations, we study the phase behavior of single and multiple semiflexible polymer chains in solution under poor-solvent conditions. In the case of a single chain, we obtain…

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