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General results from statistical learning theory suggest to understand not only brain computations, but also brain plasticity as probabilistic inference. But a model for that has been missing. We propose that inherently stochastic features…

Neural and Evolutionary Computing · Computer Science 2016-02-17 David Kappel , Stefan Habenschuss , Robert Legenstein , Wolfgang Maass

Thanks to the availability of large scale digital datasets and massive amounts of computational power, deep learning algorithms can learn representations of data by exploiting multiple levels of abstraction. These machine learning methods…

Disordered Systems and Neural Networks · Physics 2018-10-01 Alberto Testolin , Michele Piccolini , Samir Suweis

The impressive lifelong learning in animal brains is primarily enabled by plastic changes in synaptic connectivity. Importantly, these changes are not passive, but are actively controlled by neuromodulation, which is itself under the…

Neural and Evolutionary Computing · Computer Science 2021-07-06 Thomas Miconi , Aditya Rawal , Jeff Clune , Kenneth O. Stanley

The aim of the present paper is to study the effects of Hebbian learning in random recurrent neural networks with biological connectivity, i.e. sparse connections and separate populations of excitatory and inhibitory neurons. We furthermore…

Neurons and Cognition · Quantitative Biology 2007-06-19 Benoit Siri , Mathias Quoy , Bruno Delord , Bruno Cessac , Hugues Berry

Synaptic plasticity typically produces heavy-tailed distributions of synaptic strengths, consisting of a few strong connections among many weaker ones. Meanwhile, structural plasticity relies on distinct signaling cascades to reshape…

Neurons and Cognition · Quantitative Biology 2026-01-06 Jia Li , Cees van Leeuwen , Roman Bauer , Ilias Rentzeperis

Generating functionals may guide the evolution of a dynamical system and constitute a possible route for handling the complexity of neural networks as relevant for computational intelligence. We propose and explore a new objective function,…

Neurons and Cognition · Quantitative Biology 2017-11-27 Rodrigo Echeveste , Claudius Gros

The adaptive changes in synaptic efficacy that occur between spiking neurons have been demonstrated to play a critical role in learning for biological neural networks. Despite this source of inspiration, many learning focused applications…

Neural and Evolutionary Computing · Computer Science 2022-05-30 Samuel Schmidgall , Julia Ashkanazy , Wallace Lawson , Joe Hays

Correlation-based Hebbian plasticity is thought to shape neuronal connectivity during development and learning, whereas homeostatic plasticity would stabilize network activity. Here we investigate another, new aspect of this dichotomy: Can…

Neurons and Cognition · Quantitative Biology 2018-03-02 Júlia V Gallinaro , Stefan Rotter

Deep learning has achieved impressive prediction accuracies in a variety of scientific and industrial domains. However, the nested non-linear feature of deep learning makes the learning highly non-transparent, i.e., it is still unknown how…

Machine Learning · Computer Science 2020-10-26 Chan Li , Haiping Huang

The success of deep learning sparked interest in whether the brain learns by using similar techniques for assigning credit to each synaptic weight for its contribution to the network output. However, the majority of current attempts at…

Deep continual learning requires models to adapt to new tasks without retraining from scratch. However, neural networks can lose their ability to adapt to new tasks after training on previous ones, a phenomenon known as loss of plasticity.…

Machine Learning · Computer Science 2026-05-12 Jiuqi Wang , Jayanth Srinivasa , Claire Chen , Shuze Daniel Liu , Ali Payani , Shangtong Zhang

On the basis of the general form for the energy needed to adapt the connection strengths of a network in which learning takes place, a local learning rule is found for the changes of the weights. This biologically realizable learning rule…

Disordered Systems and Neural Networks · Physics 2009-10-31 M. Heerema , W. A. van Leeuwen

Cortical populations of neurons develop sparse representations adapted to the statistics of the environment. While existing synaptic plasticity models reproduce some of the observed receptive-field properties, a major obstacle is the…

Neurons and Cognition · Quantitative Biology 2022-09-16 Carlos Stein N. Brito , Wulfram Gerstner

Bayesian inference provides a principled framework for understanding brain function, while neural activity in the brain is inherently spike-based. This paper bridges these two perspectives by designing spiking neural networks that simulate…

Neurons and Cognition · Quantitative Biology 2026-01-01 Sepideh Adamiat , Wouter M. Kouw , Bert de Vries

Animal behaviour depends on learning to associate sensory stimuli with the desired motor command. Understanding how the brain orchestrates the necessary synaptic modifications across different brain areas has remained a longstanding puzzle.…

Neurons and Cognition · Quantitative Biology 2018-01-03 João Sacramento , Rui Ponte Costa , Yoshua Bengio , Walter Senn

This review explores biologically inspired learning as a model for intelligent robot control and sensing technology on the basis of specific examples. Hebbian synaptic learning is discussed as a functionally relevant model for machine…

Robotics · Computer Science 2022-02-28 Birgitta Dresp-Langley

The cortex learns to make associations between stimuli and spiking activity which supports behaviour. It does this by adjusting synaptic weights. The complexity of these transformations implies that synapses have to change without access to…

Neurons and Cognition · Quantitative Biology 2019-11-04 Johnatan Aljadeff , James D'amour , Rachel E. Field , Robert C. Froemke , Claudia Clopath

Neural networks are commonly trained to make predictions through learning algorithms. Contrastive Hebbian learning, which is a powerful rule inspired by gradient backpropagation, is based on Hebb's rule and the contrastive divergence…

Machine Learning · Computer Science 2018-06-21 Georgios Detorakis , Travis Bartley , Emre Neftci

The high computational complexity and increasing parameter counts of deep neural networks pose significant challenges for deployment in resource-constrained environments, such as edge devices or real-time systems. To address this, we…

Machine Learning · Computer Science 2025-06-17 Laura Erb , Tommaso Boccato , Alexandru Vasilache , Juergen Becker , Nicola Toschi

The brain learns abstract representations of high-dimensional sensory input, but the plasticity rules that enable such learning are unknown. We study biologically plausible algorithms on the Random Hierarchy Model (RHM), an artificial…

Machine Learning · Computer Science 2026-05-19 Ariane Delrocq , Wu S. Zihan , Guillaume Bellec , Wulfram Gerstner