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We have carried out extensive Monte Carlo simulations of the fusion of tense apposed bilayers formed by amphiphilic molecules within the framework of a coarse grained lattice model. The fusion pathway differs from the usual stalk mechanism.…

Soft Condensed Matter · Physics 2016-08-31 M. Mueller , K. Katsov , M. Schick

We extend previous work on homogeneous bilayers to calculate the barriers to fusion of planar bilayers which contain two different amphiphiles, a lamellae-former and a hexagonal former, with different compositions of the twoin each leaf.…

Soft Condensed Matter · Physics 2009-11-11 Jae Youn Lee , Michael Schick

Self-consistent field theory is used to determine structural and energetic properties of metastable intermediates and unstable transition states involved in the standard stalk mechanism of bilayer membrane fusion. A microscopic model of…

Soft Condensed Matter · Physics 2016-08-31 Kirill Katsov , Marcus Mueller , Michael Schick

We have carried out Monte Carlo simulation of the fusion of bilayers of single chain amphiphiles which show phase behavior similar to that of biological lipids. The fusion mechanism we observe is very different from the ``stalk''…

Soft Condensed Matter · Physics 2009-11-07 M. Mueller , K. Katsov , M. Schick

We use self-consistent field theory to determine structural and energetic properties of intermediates and transition states involved in bilayer membrane fusion. In particular, we extend our original calculations from those of the standard…

Soft Condensed Matter · Physics 2009-11-11 Kirill Katsov , Marcus Mueller , Michael Schick

Bilayer membranes self-assembled from amphiphilic molecules such as lipids, surfactants and block copolymers are ubiquitous in biological and physiochemical systems. The shape and structure of bilayer membranes depend crucially on their…

Soft Condensed Matter · Physics 2016-01-20 Pingwen Zhang , An-Chang Shi

We use a simple and efficient computer model to investigate the physical properties of bilayer membranes. The amphiphilic molecules are modeled as short rigid trimers with finite range pair interactions between them. The pair potentials…

Soft Condensed Matter · Physics 2009-11-10 Oded Farago

Binary mixtures of amphiphiles in solution can self-assemble into a wide range of structures when the two species individually form aggregates of different curvatures. A specific example of this is seen in solutions of lipid mixtures where…

Soft Condensed Matter · Physics 2015-03-17 M. J. Greenall , G. Gompper

In the present article we study diffuse interface models for two-phase biomembranes. We will do so by starting off with a diffuse interface model on $\mathbb{R}^n$ defined by two coupled phase fields $u,v$. The first phase field $u$ is the…

Analysis of PDEs · Mathematics 2024-07-24 Benjamin Lledos , Roberta Marziani , Heiner Olbermann

Computer simulations of coarse-grained molecular models for amphiphilic systems can provide insight into the the structure of amphiphiles at interfaces. They can help to identify the factors that determine the phase behavior, and they can…

Soft Condensed Matter · Physics 2007-05-23 Friederike Schmid , Dominik Düchs , Olaf Lenz , Claire Loison

We provide a detailed mathematical analysis of a model for phase separation on biological membranes which was recently proposed by Garcke, R\"atz, R\"oger and the second author. The model is an extended Cahn-Hilliard equation which contains…

Analysis of PDEs · Mathematics 2019-02-06 Helmut Abels , Johannes Kampmann

We study the minimizers of a degenerate case of the Ohta-Kawasaki energy, defined as the sum of the perimeter and a Coulombic nonlocal term. We start by investigating radially symmetric candidates which give us insights into the asymptotic…

Optimization and Control · Mathematics 2024-09-16 Qiang Du , James M. Scott , Zirui Xu

While biological crystallization processes have been studied on the microscale extensively, models addressing the mesoscale aspects of such phenomena are rare. In this work, we investigate whether the phase-field theory developed in…

In this paper, phase field models are developed for multi-component vesicle membranes with different lipid compositions and membranes with free boundary. These models are used to simulate the deformation of membranes under the elastic…

Biological Physics · Physics 2007-05-23 Xiaoqiang Wang , Qiang Du

We consider a phase field crystal modeling approach for binary mixtures of interacting active and passive particles. The approach allows to describe generic properties for such systems within a continuum model. We validate the approach by…

Soft Condensed Matter · Physics 2018-09-19 Francesco Alaimo , Axel Voigt

We investigate pores in fluid membranes by molecular dynamics simulations of an amphiphile-solvent mixture, using a molecular coarse-grained model. The amphiphilic membranes self-assemble into a lamellar stack of amphiphilic bilayers…

Soft Condensed Matter · Physics 2009-11-11 Claire Loison , Michel Mareschal , Friederike Schmid

Understanding the morphology formation process of solution-cast photoactive layers (PALs) is crucial to derive design rules for optimized and reliable third generation solar cell fabrication. For this purpose, a Phase-Field (PF)…

Materials Science · Physics 2023-10-19 Maxime Siber , Olivier J. J. Ronsin , Jens Harting

Phase field method is playing an increasingly important role in understanding and predicting morphological evolution in materials and biological systems. Here, we develop a new analytical approach based on bifurcation analysis to explore…

Numerical Analysis · Mathematics 2022-10-14 Xinyue Evelyn Zhao , Long-Qing Chen , Wenrui Hao , Yanxiang Zhao

Bilayer graphene has been a subject of intense study in recent years. We extend a structural phase field crystal method to include an external potential from adjacent layer(s), which is generated by the corresponding phase field and changes…

Materials Science · Physics 2020-12-24 Kai Liu

The morphogenesis of cells and tissues involves an interplay between chemical signals and active forces on their surrounding surface layers. The complex interaction of hydrodynamics and material flows on such active surfaces leads to…

Cell Behavior · Quantitative Biology 2023-06-30 Sebastian Aland , Claudia Wohlgemuth
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