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Reconstructing pathogen dynamics from genetic data as they become available during an outbreak or epidemic represents an important statistical scenario in which observations arrive sequentially in time and one is interested in performing…

Populations and Evolution · Quantitative Biology 2020-02-04 Mandev S. Gill , Philippe Lemey , Marc A. Suchard , Andrew Rambaut , Guy Baele

The ability to directly record human face-to-face interactions increasingly enables the development of detailed data-driven models for the spread of directly transmitted infectious diseases at the scale of individuals. Complete coverage of…

Cross-sectional incidence estimation based on recency testing has become a widely used tool in HIV research. Recently, this method has gained prominence in HIV prevention trials to estimate the "placebo" incidence that participants might…

Methodology · Statistics 2024-12-18 Jianan Pan , Marlena Bannick , Fei Gao

A stochastic epidemic model is defined in which each individual belongs to a household, a secondary grouping (typically school or workplace) and also the community as a whole. Moreover, infectious contacts take place in these three settings…

Applications · Statistics 2009-08-17 Tom Britton , Theodore Kypraios , Philip O'Neill

In vaccine studies for infectious diseases such as human immunodeficiency virus (HIV), the frequency and type of contacts between study participants and infectious sources are among the most informative risk factors, but are often not…

Applications · Statistics 2012-08-27 Yang Yang , Peter Gilbert , Ira M. Longini, , M. Elizabeth Halloran

In this paper, we construct a model to describe the transmission of HIV in a homogeneous host population. By considering the specific mechanism of HIV, we derive a model structured in three successive stages: (i) primary infection, (ii)…

Analysis of PDEs · Mathematics 2019-11-18 Mboya Ba , Ramsès Djidjou-Demasse , Mountaga Lam , Jean-Jules Tewa

The purpose of this study is to leverage modern technology (such as mobile or web apps in Beckman et al. (2014)) to enrich epidemiology data and infer the transmission of disease. Homogeneity related research on population level has been…

Applications · Statistics 2015-09-02 Kai Fan , Allison E. Aiello , Katherine A. Heller

The spread of infectious disease in a human community or the proliferation of fake news on social media can be modeled as a randomly growing tree-shaped graph. The history of the random growth process is often unobserved but contains…

Probability · Mathematics 2021-01-15 Harry Crane , Min Xu

In many cases, tainted information in a computer network can spread in a way similar to an epidemics in the human world. On the other had, information processing paths are often redundant, so a single infection occurrence can be easily…

Physics and Society · Physics 2024-03-07 Franco Bagnoli , Emanuele Bellini , Emanuele Massaro

The dynamics of contact networks and epidemics of infectious diseases often occur on comparable time scales. Ignoring one of these time scales may provide an incomplete understanding of the population dynamics of the infection process. We…

Populations and Evolution · Quantitative Biology 2021-02-09 Luis E C Rocha , Naoki Masuda

Background: High HIV transmission persists in many U.S. jurisdictions despite prevention efforts. HIV self-testing offers a means to overcome barriers associated with routine laboratory-based testing but carries a risk of increasing…

Dynamical Systems · Mathematics 2025-04-23 Alex Viguerie

Inference of the reproduction number through time is of vital importance during an epidemic outbreak. Typically, epidemiologists tackle this using observed prevalence or incidence data. However, prevalence and incidence data alone is often…

Methodology · Statistics 2026-03-16 Alicia Gill , Jere Koskela , Xavier Didelot , Richard G. Everitt

Acute infectious diseases are transmitted over networks of social contacts. Epidemic models are used to predict the spread of emergent pathogens and compare intervention strategies. Many of these models assume equal probability of contact…

Applications · Statistics 2016-11-25 Gail E. Potter , Niel Hens

In the study of infectious diseases on networks, researchers calculate epidemic thresholds to help forecast whether a disease will eventually infect a large fraction of a population. Because network structure typically changes in time,…

Social and Information Networks · Computer Science 2021-08-11 Qinyi Chen , Mason A. Porter

Epidemic models are invaluable tools to understand and implement strategies to control the spread of infectious diseases, as well as to inform public health policies and resource allocation. However, current modeling approaches have…

Methodology · Statistics 2026-05-12 Caitlin Ward , Rob Deardon , Alexandra M. Schmidt

Key populations at high risk of HIV infection are critical for understanding and monitoring HIV epidemics, but global estimation is hampered by sparse, uneven data. We analyze data from 199 countries for female sex workers (FSW), men who…

Applications · Statistics 2025-09-16 Jiahao Zhang , Keith Sabin , Le Bao

Identifying undocumented or potential future interactions among species is a challenge facing modern ecologists. Recent link prediction methods rely on trait data, however large species interaction databases are typically sparse and…

Applications · Statistics 2019-09-23 Mohamad Elmasri , Maxwell J. Farrell , T. Jonathan Davies , David A. Stephens

Phenotypic variability in a population of cells can work as the bet-hedging of the cells under an unpredictably changing environment, the typical example of which is the bacterial persistence. To understand the strategy to control such…

Populations and Evolution · Quantitative Biology 2019-12-02 So Nakashima , Yuki Sughiyama , Tetsuya J. Kobayashi

Epidemic disease spreading is conventionally often modelled and analyzed by means of rate and diffusion equations, following the paradigms of well-controlled chemical reactions and diffusive dynamics in a test tube. Yet, serious worries…

Physics and Society · Physics 2023-01-03 Klaus Kroy

The United Nations (UN) issued official probabilistic population projections for all countries to 2100 in July 2015. This was done by simulating future levels of total fertility and life expectancy from Bayesian hierarchical models, and…

Applications · Statistics 2016-09-15 David J. Sharrow , Jessica Godwin , Yanjun He , Samuel J. Clark , Adrian E. Raftery
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