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The use of massive survival data has become common in survival analysis. In this study, a subsampling algorithm is proposed for the Cox proportional hazards model with time-dependent covariates when the sample is extraordinarily large but…

Computation · Statistics 2023-02-07 Nan Qiao , Wangcheng Li , Feng Xiao , Cunjie Lin , Yong Zhou

Accurately predicting early recurrence in brain tumor patients following surgical resection remains a clinical challenge. This study proposes a multi-modal machine learning framework that integrates structural MRI features with clinical…

Machine Learning · Computer Science 2025-09-03 Cheng Cheng , Zeping Chen , Rui Xie , Peiyao Zheng , Xavier Wang

Quantitative medical image computing (radiomics) has been widely applied to build prediction models from medical images. However, overfitting is a significant issue in conventional radiomics, where a large number of radiomic features are…

Image and Video Processing · Electrical Eng. & Systems 2020-01-07 Jianan Chen , Laurent Milot , Helen M. C. Cheung , Anne L. Martel

Pre-trained segmentation models are a powerful and flexible tool for segmenting images. Recently, this trend has extended to medical imaging. Yet, often these methods only produce a single prediction for a given image, neglecting inherent…

Computer Vision and Pattern Recognition · Computer Science 2025-03-14 Benjamin Towle , Xin Chen , Ke Zhou

Machine-based brain tumor segmentation can help doctors make better diagnoses. However, the complex structure of brain tumors and expensive pixel-level annotations present challenges for automatic tumor segmentation. In this paper, we…

Computer Vision and Pattern Recognition · Computer Science 2024-08-05 Ruitao Xie , Limai Jiang , Xiaoxi He , Yi Pan , Yunpeng Cai

In the last few years, deep learning classifiers have shown promising results in image-based medical diagnosis. However, interpreting the outputs of these models remains a challenge. In cancer diagnosis, interpretability can be achieved by…

Computer Vision and Pattern Recognition · Computer Science 2021-06-16 Kangning Liu , Yiqiu Shen , Nan Wu , Jakub Chłędowski , Carlos Fernandez-Granda , Krzysztof J. Geras

Histopathological image segmentation is a challenging and important topic in medical imaging with tremendous potential impact in clinical practice. State of the art methods rely on hand-crafted annotations which hinder clinical translation…

Traditional survival models such as the Cox proportional hazards model are typically based on scalar or categorical clinical features. With the advent of increasingly large image datasets, it has become feasible to incorporate quantitative…

Computer Vision and Pattern Recognition · Computer Science 2020-01-09 Christoph Haarburger , Philippe Weitz , Oliver Rippel , Dorit Merhof

Building a large image dataset with high-quality object masks for semantic segmentation is costly and time consuming. In this paper, we introduce a principled semi-supervised framework that only uses a small set of fully supervised images…

Computer Vision and Pattern Recognition · Computer Science 2020-02-27 Mostafa S. Ibrahim , Arash Vahdat , Mani Ranjbar , William G. Macready

In this paper, we present a novel cross-consistency based semi-supervised approach for semantic segmentation. Consistency training has proven to be a powerful semi-supervised learning framework for leveraging unlabeled data under the…

Computer Vision and Pattern Recognition · Computer Science 2020-06-11 Yassine Ouali , Céline Hudelot , Myriam Tami

A cascade of fully convolutional neural networks is proposed to segment multi-modal Magnetic Resonance (MR) images with brain tumor into background and three hierarchical regions: whole tumor, tumor core and enhancing tumor core. The…

Computer Vision and Pattern Recognition · Computer Science 2018-07-23 Guotai Wang , Wenqi Li , Sebastien Ourselin , Tom Vercauteren

In this paper, we describe a dataset relating to cellular and physical conditions of patients who are operated upon to remove colorectal tumours. This data provides a unique insight into immunological status at the point of tumour removal,…

Machine Learning · Computer Science 2016-11-15 Chris Roadknight , Uwe Aickelin , John Scholefield , Lindy Durrant

We present the development of a semi-supervised regression method using variational autoencoders (VAE), which is customized for use in soft sensing applications. We motivate the use of semi-supervised learning considering the fact that…

Machine Learning · Computer Science 2022-12-12 Yilin Zhuang , Zhuobin Zhou , Burak Alakent , Mehmet Mercangöz

Semi-supervised learning is a model training method that uses both labeled and unlabeled data. This paper proposes a fully Bayes semi-supervised learning algorithm that can be applied to any multi-category classification problem. We assume…

Machine Learning · Statistics 2024-07-22 Rui Zhu , Shuvrarghya Ghosh , Subhashis Ghosal

Robust and generalizable segmentation of brain tumors on multi-parametric magnetic resonance imaging (MRI) remains difficult because tumor types differ widely. The BraTS 2025 Lighthouse Challenge benchmarks segmentation methods on diverse…

Brain tumor segmentation is a challenging problem in medical image analysis. The endpoint is to generate the salient masks that accurately identify brain tumor regions in an fMRI screening. In this paper, we propose a novel attention gate…

Image and Video Processing · Electrical Eng. & Systems 2021-07-08 Tim Cvetko

With nearly one million new cases diagnosed worldwide in 2020, head \& neck cancer is a deadly and common malignity. There are challenges to decision making and treatment of such cancer, due to lesions in multiple locations and outcome…

Image and Video Processing · Electrical Eng. & Systems 2023-05-17 Angel Victor Juanco Muller , Joao F. C. Mota , Keith A. Goatman , Corne Hoogendoorn

Deep co-training has recently been proposed as an effective approach for image segmentation when annotated data is scarce. In this paper, we improve existing approaches for semi-supervised segmentation with a self-paced and self-consistent…

Computer Vision and Pattern Recognition · Computer Science 2021-07-15 Ping Wang , Jizong Peng , Marco Pedersoli , Yuanfeng Zhou , Caiming Zhang , Christian Desrosiers

We propose a single neural probabilistic model based on variational autoencoder that can be conditioned on an arbitrary subset of observed features and then sample the remaining features in "one shot". The features may be both real-valued…

Machine Learning · Statistics 2019-07-01 Oleg Ivanov , Michael Figurnov , Dmitry Vetrov

Colorectal liver metastases (CLM) significantly impact colon cancer patients, influencing survival based on systemic chemotherapy response. Traditional methods like tumor grading scores (e.g., tumor regression grade - TRG) for prognosis…