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Physical and functional constraints on biological networks lead to complex topological patterns across multiple scales in their organization. A particular type of higher-order network feature that has received considerable interest is…

Quantitative Methods · Quantitative Biology 2024-10-15 Alexis Bénichou , Jean-Baptiste Masson , Christian L. Vestergaard

We introduce a method to find network motifs in knowledge graphs. Network motifs are useful patterns or meaningful subunits of the graph that recur frequently. We extend the common definition of a network motif to coincide with a basic…

Machine Learning · Statistics 2021-04-19 Peter Bloem

Motivated by applications in social network community analysis, we introduce a new clustering paradigm termed motif clustering. Unlike classical clustering, motif clustering aims to minimize the number of clustering errors associated with…

Social and Information Networks · Computer Science 2017-01-31 Pan Li , Hoang Dau , Gregory Puleo , Olgica Milenkovic

Topological network motifs represent functional relationships within and between regulatory and protein-protein interaction networks. Enriched motifs often aggregate into self-contained units forming functional modules. Theoretical models…

Molecular Networks · Quantitative Biology 2011-09-12 Tom Michoel , Anagha Joshi , Bruno Nachtergaele , Yves Van de Peer

Studying the topology of so-called real networks, that is networks obtained from sociological or biological data for instance, has become a major field of interest in the last decade. One way to deal with it is to consider that networks are…

Applications · Statistics 2010-07-27 Etienne Birmele

Networks are a fundamental tool for modeling complex systems in a variety of domains including social and communication networks as well as biology and neuroscience. Small subgraph patterns in networks, called network motifs, are crucial to…

Social and Information Networks · Computer Science 2018-01-08 Ashwin Paranjape , Austin R. Benson , Jure Leskovec

This paper looks at the task of network topology inference, where the goal is to learn an unknown graph from nodal observations. One of the novelties of the approach put forth is the consideration of prior information about the density of…

Signal Processing · Electrical Eng. & Systems 2022-07-12 Samuel Rey , T. Mitchell Roddenberry , Santiago Segarra , Antonio G. Marques

Many real world networks contain a statistically surprising number of certain subgraphs, called network motifs. In the prevalent approach to motif analysis, network motifs are detected by comparing subgraph frequencies in the original…

Social and Information Networks · Computer Science 2014-11-25 Anatol E. Wegner

We interpret the subgraph centrality as the partition function of a network. The entropy, the internal energy and the Helmholtz free energy are defined for networks and molecular graphs on the basis of graph spectral theory. Various…

Physics and Society · Physics 2009-05-27 Ernesto Estrada , Naomichi Hatano

A growing set of applications consider the process of network formation by using subgraphs as a tool for generating the network topology. One of the pressing research challenges is thus to be able to use these subgraphs to understand the…

Social and Information Networks · Computer Science 2019-04-11 Soumajyoti Sarkar , Hamidreza Alvari , Paulo Shakarian

Studying the topology of so-called {\em real networks}, that is networks obtained from sociological or biological data for instance, has become a major field of interest in the last decade. One way to deal with it is to consider that…

Applications · Statistics 2010-11-23 Etienne Birmele

The local structure of unweighted networks can be characterized by the number of times a subgraph appears in the network. The clustering coefficient, reflecting the local configuration of triangles, can be seen as a special case of this…

Statistical Mechanics · Physics 2009-11-10 J. -P. Onnela , J. Saramäki , J. Kertész , K. Kaski

Motifs are thought to be some fundamental components of social face-to-face interaction temporal networks. However, the motifs previously considered are either limited to a handful of nodes and edges, or do not include triangles, which are…

Physics and Society · Physics 2025-05-19 Didier Le Bail

Motif counting plays a crucial role in understanding the structural properties of networks. By computing motif frequencies, researchers can draw key insights into the structural properties of the underlying network. As networks become…

Social and Information Networks · Computer Science 2025-03-26 Haozhe Yin , Kai Wang , Wenjie Zhang , Yizhang He , Ying Zhang , Xuemin Lin

Several natural and theoretical networks can be broken down into smaller portions, or subgraphs corresponding to neighborhoods. The more frequent of these neighborhoods can then be understood as motifs of the network, being therefore…

Physics and Society · Physics 2022-04-21 Guilherme S. Domingues , Eric K. Tokuda , Luciano da F. Costa

We introduce a new method for finding network motifs: interesting or informative subgraph patterns in a network. Subgraphs are motifs when their frequency in the data is high compared to the expected frequency under a null model. To compute…

Machine Learning · Computer Science 2021-04-19 Peter Bloem , Steven de Rooij

Network structures are extremely important to the study of political science. Much of the data in its subfields are naturally represented as networks. This includes trade, diplomatic and conflict relationships. The social structure of…

Methodology · Statistics 2011-05-05 Drew Conway

Networks are a fundamental model of complex systems throughout the sciences, and network datasets are typically analyzed through lower-order connectivity patterns described at the level of individual nodes and edges. However, higher-order…

Social and Information Networks · Computer Science 2018-02-21 Austin R. Benson

Many real-world networks describe systems in which interactions decay with the distance between nodes. Examples include systems constrained in real space such as transportation and communication networks, as well as systems constrained in…

Statistical Mechanics · Physics 2009-11-10 Shalev Itzkovitz , Uri Alon

Exploring statistics of locally connected subgraph patterns (also known as network motifs) has helped researchers better understand the structure and function of biological and online social networks (OSNs). Nowadays the massive size of…

Social and Information Networks · Computer Science 2014-03-28 Pinghui Wang , John C. S. Lui , Bruno Ribeiro , Don Towsley , Junzhou Zhao , Xiaohong Guan
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