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X-ray phase-contrast imaging can provide greatly improved contrast over conventional absorption-based imaging for weakly absorbing samples, such as biological soft tissues and fibre composites. In this manuscript, we introduce an easy and…

Software Engineering · Computer Science 2015-04-21 Shenghao Wang , Huajie Han , Kun Gao , Zhili Wang , Can Zhang , Meng Yang , Zhao Wu , Augusto Marcelli , Ziyu Wu

New lensless diffractive X-ray technic for micro-scale imaging of biological tissue is based on quantitative phase retrieval schemes. By incorporating refraction, this method yields improved contrast compared to purely absorption-based…

Numerical Analysis · Mathematics 2018-03-28 Victor Palamodov

X-ray interferometry provides valuable information in terms of attenuation, small-angle scatter, and differential phase contrast. This multi-modal contrast can aid in many clinical applications, such as lung diseases and breast cancer.…

Optics · Physics 2026-03-12 Murtuza S. Taqi , Joyoni Dey , Hunter C. Meyer

Optical microscopy is without a doubt an essential component of life science research, but many objects of interest in biology are transparent. Chemical or immunological dyes, which can often be toxic, fluorescent transgenes, which require…

Optics · Physics 2012-09-11 Quintin Tyrell Davis

Phase-contrast X-ray imaging can improve the visibility of weakly absorbing objects (e.g. soft tissues) by an order of magnitude or more compared to conventional radiographs. Previously, it has been shown that combining phase retrieval with…

X-ray phase-contrast imaging enhances soft tissue visualization by leveraging the phase shift of X-rays passing through materials. It permits to minimize radiation exposure due to high contrast, as well as high resolution imaging limited by…

Optics · Physics 2024-03-13 Emilie Pietersoone , Jean Michel Létang , Simon Rit , Max Langer

X-ray Fluorescence Computed Tomography(XFCT) is a prevalent experimental technique which is utilized to investigate the spatial distribution of elements in sample. The sensitivity of L-shell XFCT of some elements is lower than that of…

Instrumentation and Detectors · Physics 2014-04-30 Liu Long , Huang Yang , Ma Bo , Xu Qing , Yan Lingtong , Li Li , Feng Songlin , Feng Xiangqian

X-ray phase-contrast imaging has recently led to a revolution in resolving power and tissue contrast in biomedical imaging, microscopy and materials science. The necessary high spatial coherence is currently provided by either large-scale…

Plasma Physics · Physics 2019-06-26 J. Wenz , S. Schleede , K. Khrennikov , M. Bech , P. Thibault , M. Heigoldt , F. Pfeiffer , S. Karsch

Inferior soft-tissue contrast resolution is a major limitation of current CT scanners. The aim of the study is to improve the contrast resolution of CT scanners using dual-energy acquisition. Based on dual-energy material decomposition, the…

Medical Physics · Physics 2016-11-15 Wei Zhao , Lu Wan , Bo Zhang , Qiude Zhang , Tianye Niu

Spectroscopic techniques are essential for studying material properties, but the small cross-sections of some methods may result in low signal-to-noise ratios (SNRs) in the collected spectra. In this article we present methods, based on…

In this paper we study the reconstruction of moving object densities from undersampled dynamic X-ray tomography in two dimensions. A particular motivation of this study is to use realistic measurement protocols for practical applications,…

Numerical Analysis · Mathematics 2018-03-28 Martin Burger , Hendrik Dirks , Lena Frerking , Andreas Hauptmann , Tapio Helin , Samuli Siltanen

In this paper we report a spectrometric approach to dual-energy digital radiography that has been developed and applied to identify specific organic substances and discern small differences in their effective atomic number. An experimental…

Instrumentation and Detectors · Physics 2008-10-06 S. V. Naydenov , V. D. Ryzhikov , G. M. Onyshchenko , P. Lecoq , C. Smith

Dark-field radiography is a novel X-ray imaging modality that enables complementary diagnostic information by visualizing the microstructural properties of lung tissue. Implemented via a Talbot-Lau interferometer integrated into a…

The problem of optimization of propagation-based phase-contrast imaging setups is considered in the case of projection X-ray imaging and three-dimensional tomography with phase retrieval. For two-dimensional imaging, a simple model for a…

Medical Physics · Physics 2026-03-03 T. E. Gureyev , D. M. Paganin , H. M. Quiney

The translation of an early (1957), Russian article on the development of x-ray computed tomography is provided. The article demonstrates a principle possibility of determining the local attenuation coefficient in every element of a…

History and Philosophy of Physics · Physics 2020-01-14 Alex Gustschin

X-ray speckles have been used for a wide variety of experiments, ranging from imaging (and tomography), wavefront sensing, spatial coherence measurements all the way to x-ray photon correlation spectroscopy (XPCS) and ptychography. In the…

Medical Physics · Physics 2024-04-19 Rafael Celestre , Laurene Quenot , Christopher Ninham , Emmanuel Brun , Luca Fardin

Propagation-based phase-contrast X-ray imaging is a promising technique for in~vivo medical imaging, offering lower radiation doses than traditional attenuation-based imaging. Previous studies have focused on X-ray energies below 50 keV for…

X-ray phase contrast tomography (XPCT) is widely used for 3D imaging of objects with weak contrast in X-ray absorption index but strong contrast in refractive index decrement. To reconstruct an object imaged using XPCT, phase retrieval…

Image and Video Processing · Electrical Eng. & Systems 2020-09-23 K. Aditya Mohan , Dilworth Y. Parkinson , Jefferson A. Cuadra

Photon-counting CT (PCCT) offers improved diagnostic performance through better spatial and energy resolution, but developing high-quality image reconstruction methods that can deal with these large datasets is challenging. Model-based…

Medical Physics · Physics 2022-08-09 Alma Eguizabal , Ozan Öktem , Mats U. Persson

Intrinsic imaging or intrinsic image decomposition has traditionally been described as the problem of decomposing an image into two layers: a reflectance, the albedo invariant color of the material; and a shading, produced by the…

Computer Vision and Pattern Recognition · Computer Science 2021-12-08 Elena Garces , Carlos Rodriguez-Pardo , Dan Casas , Jorge Lopez-Moreno
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