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Gaining insights from realistic dynamical models of biochemical systems can be challenging given their large number of state variables. Model reduction techniques can mitigate this by decreasing complexity by mapping the model onto a…

Computational Engineering, Finance, and Science · Computer Science 2024-11-22 Alexander Leguizamon-Robayo , Antonio Jiménez-Pastor , Micro Tribastone , Max Tschaikowski , Andrea Vandin

We simulate the collective dynamics in spin lattices with long range interactions and collective decay in one, two and three dimensions. Starting from a dynamical mean-field approach derived by local factorization of the density operator we…

Quantum Physics · Physics 2016-01-20 S. Krämer , H. Ritsch

Simulated Annealing (SA) is a widely used stochastic optimization algorithm, yet much of its theoretical understanding is limited to asymptotic convergence guarantees or general spectral bounds. In this paper, we develop a finite-time…

Systems and Control · Electrical Eng. & Systems 2026-02-11 Hansini Ramachandran , Bhaskar Krishnamachari

Gaussian processes (GPs) are important probabilistic tools for inference and learning in spatio-temporal modelling problems such as those in climate science and epidemiology. However, existing GP approximations do not simultaneously support…

Machine Learning · Computer Science 2021-06-21 Will Tebbutt , Arno Solin , Richard E. Turner

In a number of applications, particularly in financial and actuarial mathematics, it is of interest to characterize the tail distribution of a random variable $V$ satisfying the distributional equation $V\stackrel{\mathcal{D}}{=}f(V)$,…

Probability · Mathematics 2014-07-04 Jeffrey F. Collamore , Guoqing Diao , Anand N. Vidyashankar

Uncertainty propagation of large scale discrete supply chains can be prohibitive when a large number of events occur during the simulated period and discrete event simulations (DES) are costly. We present a time bucket method to approximate…

Computation · Statistics 2019-01-17 Nai-Yuan Chiang , Yinqing Lin , Quan Long

In this paper we consider the problem of parameter inference for Markov jump process (MJP) representations of stochastic kinetic models. Since transition probabilities are intractable for most processes of interest yet forward simulation is…

Computation · Statistics 2014-09-16 Andrew Golightly , Darren J. Wilkinson

Discrete-state, continuous-time Markov models are becoming commonplace in the modelling of biochemical processes. The mathematical formulations that such models lead to are opaque, and, due to their complexity, are often considered…

Quantitative Methods · Quantitative Biology 2017-10-31 Christopher Lester

We are interested in the connection between a metastable continuous state space Markov process (satisfying e.g. the Langevin or overdamped Langevin equation) and a jump Markov process in a discrete state space. More precisely, we use the…

Probability · Mathematics 2017-02-08 Giacomo Di Gesù , Tony Lelièvre , Dorian Le Peutrec , Boris Nectoux

Let X_t, 0<=t<=T be a one-dimensional stochastic process with independent and stationary increments. This paper considers the problem of stopping the process X_t "as close as possible" to its eventual supremum M_T:=sup{X_t: 0<=t<=T}, when…

Probability · Mathematics 2012-03-21 Pieter C. Allaart

The study of animal movement is challenging because it is a process modulated by many factors acting at different spatial and temporal scales. Several models have been proposed which differ primarily in the temporal conceptualization,…

We report a novel hybrid method of simultaneous atomistic simulation of solids in critical regions (contacts surfaces, cracks areas, etc.), along with continuum modeling of other parts. The continuum is treated in terms of quasi-atoms of…

Materials Science · Physics 2026-02-17 Artem Chuprov , Egor E. Nuzhin , Alexey A. Tsukanov , Nikolay V. Brilliantov

This paper presents a novel approach to level set estimation for any function/simulation with an arbitrary number of continuous inputs and arbitrary numbers of continuous responses. We present a method that uses existing data from computer…

Methodology · Statistics 2024-07-09 David Edwards , Julie Bessac , Franck Cappello , Scotland Leman

The computer simulation of many molecular processes is complicated by long time scales caused by rare transitions between long-lived states. Here, we propose a new approach to simulate such rare events, which combines transition path…

Computational Physics · Physics 2023-03-23 Sebastian Falkner , Alessandro Coretti , Christoph Dellago

Elliptical slice sampling, when adapted to linearly truncated multivariate normal distributions, is a rejection-free Markov chain Monte Carlo method. At its core, it requires analytically constructing an ellipse-polytope intersection. The…

Machine Learning · Computer Science 2024-07-16 Kaiwen Wu , Jacob R. Gardner

We investigate a generic, parallel replica-exchange framework for Monte Carlo simulations based on the Wang-Landau method. To demonstrate its advantages and general applicability for massively parallel simulations of complex systems, we…

Computational Physics · Physics 2015-06-22 Thomas Vogel , Ying Wai Li , Thomas Wüst , David P. Landau

Stochastic sampling based trackers have shown good performance for abrupt motion tracking so that they have gained popularity in recent years. However, conventional methods tend to use a two-stage sampling paradigm, in which the search…

Computer Vision and Pattern Recognition · Computer Science 2015-03-11 Tianfei Zhou , Yao Lu , Feng Lv , Huijun Di , Qingjie Zhao , Jian Zhang

We introduce $(\varepsilon, \delta)$-bisimulation, a novel type of approximate probabilistic bisimulation for continuous-time Markov chains. In contrast to related notions, $(\varepsilon, \delta)$-bisimulation allows the use of different…

Logic in Computer Science · Computer Science 2025-05-23 Timm Spork , Christel Baier , Joost-Pieter Katoen , Sascha Klüppelholz , Jakob Piribauer

Simulating time evolution under quantum Hamiltonians is one of the most natural applications of quantum computers. We introduce TE-PAI, which simulates time evolution exactly by sampling random quantum circuits for the purpose of estimating…

Quantum Physics · Physics 2025-10-24 Chusei Kiumi , Bálint Koczor

We present approaches to quickly simulate systematics affecting CMB observations, including the effects of the scanning strategy. Using summary properties of the scan we capture features of full time ordered data (TOD) simulations, allowing…

Cosmology and Nongalactic Astrophysics · Physics 2022-03-14 Nialh McCallum , Daniel B. Thomas , Michael L. Brown