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Cross-modal fusion of different types of neuroimaging data has shown great promise for predicting the progression of Alzheimer's Disease(AD). However, most existing methods applied in neuroimaging can not efficiently fuse the functional and…

Image and Video Processing · Electrical Eng. & Systems 2022-07-15 Junren Pan , Shuqiang Wang

Functional connectivity refers to the temporal statistical relationship between spatially distinct brain regions and is usually inferred from the time series coherence/correlation in brain activity between regions of interest. In human…

Machine Learning · Statistics 2015-03-02 Shaurabh Nandy , Richard M. Golden

Brain function emerges from coordinated activity across anatomically connected regions, where structural connectivity (SC) -- the network of white matter pathways - provides the physical substrate for functional connectivity (FC) -- the…

Neurons and Cognition · Quantitative Biology 2025-07-09 Sam Frank Kelemen , Joaquín Gõni , Sérgio Pequito , Arian Ashourvan

Major depressive disorder (MDD) is a common neuropsychiatric condition whose accurate diagnosis from resting-state functional magnetic resonance imaging (rs-fMRI) remains difficult. Dynamic functional connectivity (DFC) captures…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Muhammad Asif Hasan , Yanming Zhu , Xuefei Yin , Alan Wee-Chung Liew

Brain network analysis has emerged as pivotal method for gaining a deeper understanding of brain functions and disease mechanisms. Despite the existence of various network construction approaches, shortcomings persist in the learning of…

Computer Vision and Pattern Recognition · Computer Science 2023-11-10 Yongcheng Zong , Shuqiang Wang

Experimental fMRI studies have shown that spontaneous brain activity i.e. in the absence of any external input, exhibit complex spatial and temporal patterns of co-activity between segregated brain regions. These so-called large-scale…

Adaptation and Self-Organizing Systems · Physics 2015-06-23 Vesna Vuksanović , Philipp Hövel

Functional magnetic resonance imaging (fMRI) has become one of the most common imaging modalities for brain function analysis. Recently, graph neural networks (GNN) have been adopted for fMRI analysis with superior performance.…

Neurons and Cognition · Quantitative Biology 2022-11-02 Yue Yu , Xuan Kan , Hejie Cui , Ran Xu , Yujia Zheng , Xiangchen Song , Yanqiao Zhu , Kun Zhang , Razieh Nabi , Ying Guo , Chao Zhang , Carl Yang

Brain activity is intrinsically a neural dynamic process constrained by anatomical space. This leads to significant variations in spatial distribution patterns and correlation patterns of neural activity across variable and heterogeneous…

Machine Learning · Computer Science 2026-03-10 Hongjie Jiang , Yifei Tang , Shuqiang Wang

This study introduces a pioneering approach in brain-computer interface (BCI) technology, featuring our novel concept of high-level visual imagery for non-invasive electroencephalography (EEG)-based communication. High-level visual imagery,…

Human-Computer Interaction · Computer Science 2025-11-03 Byoung-Hee Kwon , Minji Lee , Seong-Whan Lee

Background: Recent studies have indicated that functional connectivity is dynamic even during rest. A common approach to modeling the dynamic functional connectivity in whole-brain resting-state fMRI is to compute the correlation between…

Neurons and Cognition · Quantitative Biology 2019-11-05 Shih-Gu Huang , S. Balqis Samdin , Chee-Ming Ting , Hernando Ombao , Moo K. Chung

Multimodal neuroimaging modeling has becomes a widely used approach but confronts considerable challenges due to heterogeneity, which encompasses variability in data types, scales, and formats across modalities. This variability…

Neurons and Cognition · Quantitative Biology 2025-04-15 Gang Qu , Ziyu Zhou , Vince D. Calhoun , Aiying Zhang , Yu-Ping Wang

Dynamic functional connectivity (dFC) derived from resting-state functional magnetic resonance imaging (fMRI) has been extensively utilized in brain science research. The sliding window correlation (SWC) method is a widely used approach for…

Neurons and Cognition · Quantitative Biology 2026-03-27 Jinlong Hu , Jiatong Huang , Zijian Cai

To characterize atypical brain dynamics under diseases, prevalent studies investigate functional magnetic resonance imaging (fMRI). However, most of the existing analyses compress rich spatial-temporal information as the brain functional…

Image and Video Processing · Electrical Eng. & Systems 2023-05-08 Xiaozhao Liu , Mianxin Liu , Lang Mei , Yuyao Zhang , Feng Shi , Han Zhang , Dinggang Shen

Nearly one in five adolescents currently live with a diagnosed mental or behavioral health condition, such as anxiety, depression, or conduct disorder, underscoring the urgency of developing accurate and interpretable diagnostic tools.…

Machine Learning · Computer Science 2025-10-07 Song Wang , Zhenyu Lei , Zhen Tan , Jundong Li , Javier Rasero , Aiying Zhang , Chirag Agarwal

The joint analysis of multimodal neuroimaging data is critical in the field of brain research because it reveals complex interactive relationships between neurobiological structures and functions. In this study, we focus on investigating…

Methodology · Statistics 2025-03-25 Tong Lu , Yuan Zhang , Vince Lyzinski , Chuan Bi , Peter Kochunov , Elliot Hong , Shuo Chen

Functional brain networks can change rapidly as a function of stimuli or cognitive shifts. Tracking dynamic functional connectivity is particularly challenging as it requires estimating the structure of the network at each moment as well as…

Methodology · Statistics 2024-04-30 Wan-Chi Hsin , Uri T. Eden , Emily P. Stephen

This work considers a continuous framework to characterize the population-level variability of structural connectivity. Our framework assumes the observed white matter fiber tract endpoints are driven by a latent random function defined…

Computation · Statistics 2022-07-19 William Consagra , Martin Cole , Zhengwu Zhang

Recent studies in neuroscience highlight the significant potential of brain connectivity networks, which are commonly constructed from functional magnetic resonance imaging (fMRI) data for brain disorder diagnosis. Traditional brain…

Simultaneous modeling of the spatio-temporal variation patterns of brain functional network from 4D fMRI data has been an important yet challenging problem for the field of cognitive neuroscience and medical image analysis. Inspired by the…

Computer Vision and Pattern Recognition · Computer Science 2021-03-24 Yu Zhao , Xiang Li , Wei Zhang , Shijie Zhao , Milad Makkie , Mo Zhang , Quanzheng Li , Tianming Liu

Elucidating the intricate relationship between brain structure and function, both in healthy and pathological conditions, is a key challenge for modern neuroscience. Recent technical and methodological progress in neuroimaging has helped…

Neurons and Cognition · Quantitative Biology 2015-05-01 Ibai Diez , Paolo Bonifazi , Iñaki Escudero , Beatriz Mateos , Miguel A. Muñoz , Sebastiano Stramaglia , Jesus M. Cortes