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Functional connectivity (FC) refers to the investigation of interactions between brain regions to understand integration of neural activity in several regions. FC is often estimated using functional magnetic resonance images (fMRI). There…

Applications · Statistics 2023-01-24 Nathan Tung , Jerome Sanes , Eli Upfal , Ani Eloyan

Dynamic functional connectivity is an effective measure for the brain's responses to continuous stimuli. We propose an inferential method to detect the dynamic changes of brain networks based on time-varying graphical models. Whereas most…

Applications · Statistics 2020-06-23 Dingjue Ji , Junwei Lu , Yiliang Zhang , Hongyu Zhao , Siyuan Gao

Dynamic functional connectivity (dFC) using resting-state functional magnetic resonance imaging (rs-fMRI) is an advanced technique for capturing the dynamic changes of neural activities, and can be very useful in the studies of brain…

Image and Video Processing · Electrical Eng. & Systems 2025-01-29 Jing Zhang , Yanjun Lyu , Xiaowei Yu , Lu Zhang , Chao Cao , Tong Chen , Minheng Chen , Yan Zhuang , Tianming Liu , Dajiang Zhu

Understanding the evolution of brain functional networks over time is of great significance for the analysis of cognitive mechanisms and the diagnosis of neurological diseases. Existing methods often have difficulty in capturing the…

Machine Learning · Computer Science 2025-10-30 Tianqi Guo , Liping Chen , Ciyuan Peng , Jingjing Zhou , Jing Ren

Dynamic functional connectivity (DFC) analysis involves measuring correlated neural activity over time across multiple brain regions. Significant regional correlations among neural signals, such as those obtained from resting-state…

Dynamic functional connectivity analysis provides valuable information for understanding brain functional activity underlying different cognitive processes. Besides sliding window based approaches, a variety of methods have been developed…

Computer Vision and Pattern Recognition · Computer Science 2018-09-18 Hongming Li , Yong Fan

Most generally, dynamic functional connectivity (FC) refers to the non-instantaneous couplings across timeseries from a set of brain areas, here as measured by fMRI. This is in contrast to static FC, which is defined as purely instantaneous…

Neurons and Cognition · Quantitative Biology 2023-01-10 Christine Ahrends , Diego Vidaurre

Time Varying Functional Connectivity (TVFC) investigates how the interactions among brain regions vary over the course of an fMRI experiment. The transitions between different individual connectivity states can be modulated by changes in…

In recent years, there has been strong interest in neuroscience studies to investigate brain organization through networks of brain regions that demonstrate strong functional connectivity (FC). These networks are extracted from observed…

Applications · Statistics 2017-03-14 Phebe Brenne Kemmer , F. DuBois Bowman , Helen Mayberg , Ying Guo

Resting-state functional magnetic resonance imaging (rs-fMRI) is a noninvasive technique pivotal for understanding human neural mechanisms of intricate cognitive processes. Most rs-fMRI studies compute a single static functional…

Neurons and Cognition · Quantitative Biology 2025-02-25 Bishal Thapaliya , Robyn Miller , Jiayu Chen , Yu-Ping Wang , Esra Akbas , Ram Sapkota , Bhaskar Ray , Pranav Suresh , Santosh Ghimire , Vince Calhoun , Jingyu Liu

Human brain functional connectivity (FC) is often measured as the similarity of functional MRI responses across brain regions when a brain is either resting or performing a task. This paper aims to statistically analyze the dynamic nature…

Computer Vision and Pattern Recognition · Computer Science 2024-10-30 Mengyu Dai , Zhengwu Zhang , Anuj Srivastava

MRI-based modeling of brain networks has been widely used to understand functional and structural interactions and connections among brain regions, and factors that affect them, such as brain development and disease. Graph mining on brain…

Machine Learning · Computer Science 2022-05-18 Haoteng Tang , Xiyao Fu , Lei Guo , Yalin Wang , Scott Mackin , Olusola Ajilore , Alex Leow , Paul Thompson , Heng Huang , Liang Zhan

The study of dynamic functional connectomes has provided valuable insights into how patterns of brain activity change over time. Neural networks process information through artificial neurons, conceptually inspired by patterns of activation…

Neurons and Cognition · Quantitative Biology 2025-08-12 Yutong Wu , Peilin He , Tananun Songdechakraiwut

Understanding the dynamic reorganization of brain networks is critical for predicting cognitive decline, neurological progression, and individual variability in clinical outcomes. This work proposes a multimodal graph neural network…

Machine Learning · Computer Science 2026-02-11 Preksha Girish , Rachana Mysore , Kiran K. N. , Hiranmayee R. , Shipra Prashanth , Shrey Kumar

Understanding the relationship between the dynamics of neural processes and the anatomical substrate of the brain is a central question in neuroscience. On the one hand, modern neuroimaging technologies, such as diffusion tensor imaging,…

Objective motor skill assessment plays a critical role in fields such as surgery, where proficiency is vital for certification and patient safety. Existing assessment methods, however, rely heavily on subjective human judgment, which…

Neurons and Cognition · Quantitative Biology 2025-02-20 Anil Kamat , Rahul Rahul , Anirban Dutta , Lora Cavuoto , Uwe Kruger , Harry Burke , Matthew Hackett , Jack Norfleet , Steven Schwaitzberg , Suvranu De

With the advances in high resolution neuroimaging, there has been a growing interest in the detection of functional brain connectivity. Complex network theory has been proposed as an attractive mathematical representation of functional…

Neural and Evolutionary Computing · Computer Science 2018-09-18 Arash Golibagh Mahyari , Selin Aviyente

Finding an appropriate representation of dynamic activities in the brain is crucial for many downstream applications. Due to its highly dynamic nature, temporally averaged fMRI (functional magnetic resonance imaging) can only provide a…

Machine Learning · Computer Science 2022-08-18 Sikun Lin , Shuyun Tang , Scott Grafton , Ambuj Singh

Brain functional connectivity (FC) extracted from resting-state fMRI (RS-fMRI) has become a popular approach for disease diagnosis, where discriminating subjects with mild cognitive impairment (MCI) from normal controls (NC) is still one of…

Computer Vision and Pattern Recognition · Computer Science 2018-08-31 Weizheng Yan , Han Zhang , Jing Sui , Dinggang Shen

Human brains exhibit highly organized multiscale neurophysiological dynamics. Understanding those dynamic changes and the neuronal networks involved is critical for understanding how the brain functions in health and disease. Functional…

Neurons and Cognition · Quantitative Biology 2024-09-09 Manuel Morante , Kristian Frølich , Naveed ur Rehman
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