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Reaction networks are a general formalism for describing collections of classical entities interacting in a random way. While reaction networks are mainly studied by chemists, they are equivalent to Petri nets, which are used for similar…

Mathematical Physics · Physics 2021-11-23 John C. Baez

Reinforcement Learning (RL) controllers have generated excitement within the control community. The primary advantage of RL controllers relative to existing methods is their ability to optimize uncertain systems independently of explicit…

Machine Learning · Computer Science 2021-12-07 Max Mowbray , Panagiotis Petsagkourakis , Ehecatl Antonio del Río Chanona , Dongda Zhang

We present a data-driven verification approach that determines whether or not a given chemical reaction network (CRN) satisfies a given property, expressed as a formula in a modal logic. Our approach consists of three phases, integrating…

Computational Engineering, Finance, and Science · Computer Science 2020-04-24 Gareth W. Molyneux , Viraj B. Wijesuriya , Alessandro Abate

Cells are regulated by networks of controllers having many targets, and targets affected by many controllers, but these "many-to-many" combinatorial control systems are poorly understood. Here we analyze distinct cellular networks…

Molecular Networks · Quantitative Biology 2012-01-06 Jacob D. Feala , Jorge Cortes , Phillip M. Duxbury , Andrew D. McCulloch , Carlo Piermarocchi , Giovanni Paternostro

We introduce a novel self-supervised deep clustering approach tailored for unstructured data without requiring prior knowledge of the number of clusters, termed Adaptive Self-supervised Robust Clustering (ASRC). In particular, ASRC…

Machine Learning · Computer Science 2024-07-31 Chen-Lu Ding , Jiancan Wu , Wei Lin , Shiyang Shen , Xiang Wang , Yancheng Yuan

Wasserstein distributionally robust control (DRC) recently emerges as a principled paradigm for handling uncertainty in stochastic dynamical systems. However, it constructs data-driven ambiguity sets via uniform distribution shifts before…

Optimization and Control · Mathematics 2025-10-14 Jingyi Wu , Chao Ning , Yang Shi

In this paper, the issue of mixed-triggered reliable dissipative control is investigated for singular networked cascade control systems (NCCSs) with actuator saturation and randomly occurring cyber attacks. In order to utilize the limited…

Optimization and Control · Mathematics 2019-03-05 Sathishkumar Murugesan , Yen-Chen Liu

Distributionally robust control is a well-studied framework for optimal decision making under uncertainty, with the objective of minimizing an expected cost function over control actions, assuming the most adverse probability distribution…

Systems and Control · Electrical Eng. & Systems 2025-08-12 Alexandros E. Tzikas , Lukas Fiechtner , Arec Jamgochian , Mykel J. Kochenderfer

Stochastic model predictive control has been a successful and robust control framework for many robotics tasks where the system dynamics model is slightly inaccurate or in the presence of environment disturbances. Despite the successes, it…

Robotics · Computer Science 2022-04-07 Rel Guzman , Rafael Oliveira , Fabio Ramos

We construct two error feedback controllers for robust output tracking and disturbance rejection of a regular linear system with nonsmooth reference and disturbance signals. We show that for sufficiently smooth signals the output converges…

Optimization and Control · Mathematics 2023-03-01 Lassi Paunonen

Genetic regulatory networks (GRNs) have been widely studied, yet there is a lack of understanding with regards to the final size and properties of these networks, mainly due to no network currently being complete. In this study, we analyzed…

Molecular Networks · Quantitative Biology 2019-03-13 Adrian I. Campos-González , Julio A. Freyre-González

We propose a learning-based, distributionally robust model predictive control approach towards the design of adaptive cruise control (ACC) systems. We model the preceding vehicle as an autonomous stochastic system, using a hybrid model with…

Systems and Control · Electrical Eng. & Systems 2020-05-07 Mathijs Schuurmans , Alexander Katriniok , Hongtei Eric Tseng , Panagiotis Patrinos

In this paper, the applicability of the entropy method for the trend towards equilibrium for reaction-diffusion systems arising from first order chemical reaction networks is studied. In particular, we present a suitable entropy structure…

Analysis of PDEs · Mathematics 2016-12-19 Klemens Fellner , Wolfgang Prager , Bao Q. Tang

We study continuity and robustness properties of infinite-horizon average expected cost problems with respect to (controlled) transition kernels, and applications of these results to the problem of robustness of control policies designed…

Systems and Control · Electrical Eng. & Systems 2020-12-22 Ali Devran Kara , Maxim Raginsky , Serdar Yuksel

In this essay, we investigate some relations between Chemical Reaction Networks (CRN) and Mathematical Epidemiology (ME) and report on several pleasant surprises which we had simply by putting these two topics together. Firstly, we propose…

Molecular Networks · Quantitative Biology 2025-05-22 Florin Avram , Rim Adenane , Andrei D. Halanay , Matthew D. Johnston

Network controllability robustness reflects how well a networked system can maintain its controllability against destructive attacks. Its measure is quantified by a sequence of values that record the remaining controllability of the network…

Physics and Society · Physics 2022-10-14 Yang Lou , Yaodong He , Lin Wang , Kim Fung Tsang , Guanrong Chen

We propose novel chemical reaction networks to translate levels of concentration into unique DNA strand species, which we call concentration translators. Our design of the concentration translators is based on combination of two chemical…

Molecular Networks · Quantitative Biology 2021-02-23 Toshiyuki Yamane , Eiji Nakamura , Koji Masuda

Chemical reactions occur in energy, environmental, biological, and many other natural systems, and the inference of the reaction networks is essential to understand and design the chemical processes in engineering and life sciences. Yet,…

Molecular Networks · Quantitative Biology 2021-01-22 Weiqi Ji , Sili Deng

The control of nonlinear systems with unknown dynamics has been a significant field of research for many years. This paper presents a novel data-driven optimal adaptive control structure with less control effort and faster adaptation than…

Systems and Control · Electrical Eng. & Systems 2022-06-28 Mohammad Mahmoudi , Nasser Sadati

This paper considers the robustness of event-triggered control of general linear systems against additive or multiplicative frequency-domain uncertainties. It is revealed that in static or dynamic event triggering mechanisms, the sampling…

Systems and Control · Electrical Eng. & Systems 2022-03-07 Shiqi Zhang , Zhongkui Li
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