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The development of personalized human head models from medical images has become an important topic in the electromagnetic dosimetry field, including the optimization of electrostimulation, safety assessments, etc. Human head models are…

Image and Video Processing · Electrical Eng. & Systems 2020-02-24 Essam A. Rashed , Jose Gomez-Tames , Akimasa Hirata

Electro-stimulation or modulation of deep brain regions is commonly used in clinical procedures for the treatment of several nervous system disorders. In particular, transcranial direct current stimulation (tDCS) is widely used as an…

Image and Video Processing · Electrical Eng. & Systems 2020-04-29 Essam A. Rashed , Jose Gomez-Tames , Akimasa Hirata

Transcranial magnetic stimulation (TMS) is a technique for noninvasively stimulating a brain area for therapeutic, rehabilitation treatments and neuroscience research. Despite our understanding of the physical principles and experimental…

Neurons and Cognition · Quantitative Biology 2020-12-30 Jose Gomez-Tames , Ilkka Laakso , Akimasa Hirata

Objective. Personalized transcranial electrical stimulation (tES) has gained growing attention due to the substantial inter-individual variability in brain anatomy and physiology. While previous reviews have discussed the physiological…

Neurons and Cognition · Quantitative Biology 2025-11-06 Mo Wang , Kexin Zheng , Yingyue Xin , Xiang Chen , Yiling Liu , Huichun Luo , Jingsheng Tang , Tifei Yuan , Hongkai Wen , Pengfei Wei , Quanying Liu

In several diagnosis and therapy procedures based on electrostimulation effect, the internal physical quantity related to the stimulation is the induced electric field. To estimate the induced electric field in an individual human model,…

Medical Physics · Physics 2021-02-03 Essam A. Rashed , Jose Gomez-Tames , Akimasa Hirata

A major shortcoming of medical practice is the lack of an objective measure of conscious level. Impairment of consciousness is common, e.g. following brain injury and seizures, which can also interfere with sensory processing and volitional…

Neurons and Cognition · Quantitative Biology 2025-12-24 Alexis Pomares Pastor , Ines Ribeiro Violante , Gregory Scott

Accurate electromagnetic modeling of the head of a subject is of main interest in the fields of source reconstruction and brain stimulation. Those processes rely heavily on the quality of the model and, even though the geometry of the…

Medical Physics · Physics 2022-02-15 Martin Grignard , Christophe Geuzaine , Christophe Phillips

Assigning accurate conductivity values in human head models is an essential factor for performing precise electroencephalographic (EEG) source localization and targeting of transcranial electrical stimulation (TES). Unfortunately, the…

Neurons and Cognition · Quantitative Biology 2022-03-11 Hamza Altakroury , Laurent Koessler , Radu Ranta , Janis Hofmanis , Sophie Colnat Coulbois , Louis Maillard , Valérie Louis Dorr

We propose a noninvasive and dispersive framework for estimating the spatially nonuniform conductivity of brain tumors using MR images. The method consists of two components: (i) voxel-wise assignment of tumor conductivity based on…

Medical Physics · Physics 2025-09-19 Yoshiki Kubota , Yosuke Nagata , Manabu Tamura , Akimasa Hirata

For decades, focal non-invasive neuromodulation of deep brain regions has not been possible because of the steep depth-focality trade-off of conventional non-invasive brain stimulation (NIBS) techniques, such as transcranial magnetic…

Neurons and Cognition · Quantitative Biology 2025-12-17 Pierre Vassiliadis , Elena Beanato , Maximilian J. Wessel , Friedhelm C. Hummel

Purpose: Conventional automated segmentation of the head anatomy in MRI distinguishes different brain and non-brain tissues based on image intensities and prior tissue probability maps (TPM). This works well for normal head anatomies, but…

Image and Video Processing · Electrical Eng. & Systems 2021-05-20 Lukas Hirsch , Yu Huang , Lucas C Parra

Background: Transcranial magnetic stimulation (TMS) is a powerful tool to investigate neurophysiology of the human brain and treat brain disorders. Traditionally, therapeutic TMS has been applied in a one-size-fits-all approach,…

Transcranial magnetic stimulation (TMS) is a popular method for the noninvasive stimulation of neurons in the brain. It has become a standard instrument in experimental brain research and is approved for a range of diagnostic and…

Medical Physics · Physics 2023-12-27 Max Koehler , Stefan Goetz

At the group-level, deep brain stimulation leads to significant therapeutic benefit in a multitude of neurological and neuropsychiatric disorders. At the single-patient level, however, symptoms may sometimes persist despite "optimal"…

Objective: Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique used to generate conduction currents in the head and disrupt brain functions. To rapidly evaluate the tDCS-induced current density in…

Quantitative Methods · Quantitative Biology 2022-10-07 Xiaofan Jia , Sadeed Bin Sayed , Nahian Ibn Hasan , Luis J. Gomez , Guang-Bin Huang , Abdulkadir C. Yucel

Transcranial electric stimulation (TES) can modulate intrinsic neural activity in the brain by injecting weak currents through electrodes attached to the scalp. TES has been widely used as a neuroscience tool to investigate how behavioural…

Brains with complex distortion of cerebral anatomy present several challenges to automatic tissue segmentation methods of T1-weighted MR images. First, the very high variability in the morphology of the tissues can be incompatible with the…

Tissues and Organs · Quantitative Biology 2020-03-25 Gabriele Amorosino , Denis Peruzzo , Pietro Astolfi , Daniela Redaelli , Paolo Avesani , Filippo Arrigoni , Emanuele Olivetti

We present a real-time visualization system for Transcranial Magnetic Stimulation (TMS), a non-invasive neuromodulation technique for treating various brain disorders and mental health diseases. Our solution targets the current challenges…

Signal Processing · Electrical Eng. & Systems 2024-03-14 Loraine Franke , Tae Young Park , Jie Luo , Yogesh Rathi , Steve Pieper , Lipeng Ning , Daniel Haehn

Segmenting a structural magnetic resonance imaging (MRI) scan is an important pre-processing step for analytic procedures and subsequent inferences about longitudinal tissue changes. Manual segmentation defines the current gold standard in…

Computer Vision and Pattern Recognition · Computer Science 2017-06-07 Alex Fedorov , Jeremy Johnson , Eswar Damaraju , Alexei Ozerin , Vince Calhoun , Sergey Plis

In this study, we propose a neural network approach to capture the functional connectivities among anatomic brain regions. The suggested approach estimates a set of brain networks, each of which represents the connectivity patterns of a…

Computer Vision and Pattern Recognition · Computer Science 2018-07-24 Baran Baris Kivilcim , Itir Onal Ertugrul , Fatos T. Yarman Vural
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