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Over the long history of machine learning, which dates back several decades, recurrent neural networks (RNNs) have been used mainly for sequential data and time series and generally with 1D information. Even in some rare studies on 2D…

Computer Vision and Pattern Recognition · Computer Science 2021-03-05 Nguyen Huu Phong , Bernardete Ribeiro

Mathematical modeling offers a valuable approach to understanding Alzheimers disease (AD) given its complexity, unknown causes, and lack of effective treatments. Models, once validated, offer a powerful tool to test medical hypotheses that…

Analysis of PDEs · Mathematics 2026-03-20 G. Landi , A. Scaravelli , M. C. Tesi , C. Testa

This paper presents a new algorithm, Evolutionary eXploration of Augmenting Memory Models (EXAMM), which is capable of evolving recurrent neural networks (RNNs) using a wide variety of memory structures, such as Delta-RNN, GRU, LSTM, MGU…

Neural and Evolutionary Computing · Computer Science 2019-02-12 Alexander Ororbia , Ahmed Ahmed Elsaid , Travis Desell

Applying network science approaches to investigate the functions and anatomy of the human brain is prevalent in modern medical imaging analysis. Due to the complex network topology, for an individual brain, mining a discriminative network…

Computer Vision and Pattern Recognition · Computer Science 2020-07-21 Wen Zhang , Liang Zhan , Paul Thompson , Yalin Wang

This paper presents a general framework for obtaining interpretable multivariate discriminative models that allow efficient statistical inference for neuroimage analysis. The framework, termed generative discriminative machine (GDM),…

Applications · Statistics 2019-06-04 Erdem Varol , Aristeidis Sotiras , Ke Zeng , Christos Davatzikos

Alzheimer's Disease (AD) is an irreversible neurodegenerative disease characterized by progressive cognitive decline as its main symptom. In the research field of deep learning-assisted diagnosis of AD, traditional convolutional neural…

Image and Video Processing · Electrical Eng. & Systems 2025-07-15 Yang Ming , Jiang Shi Zhong , Zhou Su Juan

As societies around the world are ageing, the number of Alzheimer's disease (AD) patients is rapidly increasing. To date, no low-cost, non-invasive biomarkers have been established to advance the objectivization of AD diagnosis and…

Data-driven modeling of human motions is ubiquitous in computer graphics and computer vision applications, such as synthesizing realistic motions or recognizing actions. Recent research has shown that such problems can be approached by…

Graphics · Computer Science 2019-08-21 He Wang , Edmond S. L. Ho , Hubert P. H. Shum , Zhanxing Zhu

A model of associative memory is studied, which stores and reliably retrieves many more patterns than the number of neurons in the network. We propose a simple duality between this dense associative memory and neural networks commonly used…

Neural and Evolutionary Computing · Computer Science 2017-03-28 Dmitry Krotov , John J Hopfield

As aliasing artefacts are highly structural and non-local, many MRI reconstruction networks use pooling to enlarge filter coverage and incorporate global context. However, this inadvertently impedes fine detail recovery as downsampling…

Image and Video Processing · Electrical Eng. & Systems 2023-12-01 Wendi Ma , Marlon Bran Lorenzana , Wei Dai , Hongfu Sun , Shekhar S. Chandra

Recently, growth in our understanding of the computations performed in both biological and artificial neural networks has largely been driven by either low-level mechanistic studies or global normative approaches. However, concrete…

Neurons and Cognition · Quantitative Biology 2023-12-25 Michael Kuoch , Chi-Ning Chou , Nikhil Parthasarathy , Joel Dapello , James J. DiCarlo , Haim Sompolinsky , SueYeon Chung

At present, the vast majority of building blocks, techniques, and architectures for deep learning are based on real-valued operations and representations. However, recent work on recurrent neural networks and older fundamental theoretical…

Clinical data from electronic medical records, registries or trials provide a large source of information to apply machine learning methods in order to foster precision medicine, e.g. by finding new disease phenotypes or performing…

Machine Learning · Computer Science 2020-08-17 Maria Hügle , Gabriel Kalweit , Thomas Huegle , Joschka Boedecker

Complex-valued Neural Networks (CVNNs) are often motivated by domains where information is naturally encoded in magnitude and phase. Yet complex-valued inputs alone do not determine when complex arithmetic improves learning: the label…

Machine Learning · Computer Science 2026-05-28 Ashutosh Kumar

In this study, we propose a neural network approach to capture the functional connectivities among anatomic brain regions. The suggested approach estimates a set of brain networks, each of which represents the connectivity patterns of a…

Computer Vision and Pattern Recognition · Computer Science 2018-07-24 Baran Baris Kivilcim , Itir Onal Ertugrul , Fatos T. Yarman Vural

Unveiling pathological brain changes associated with Alzheimer's disease (AD) is a challenging task especially that people do not show symptoms of dementia until it is late. Over the past years, neuroimaging techniques paved the way for…

Quantitative Methods · Quantitative Biology 2018-08-07 Mayssa Soussia , Islem Rekik

Machine learning methods have shown large potential for the automatic early diagnosis of Alzheimer's Disease (AD). However, some machine learning methods based on imaging data have poor interpretability because it is usually unclear how…

Neuronal systems need to process temporal signals. We here show how higher-order temporal (co-)fluctuations can be employed to represent and process information. Concretely, we demonstrate that a simple biologically inspired feedforward…

Neurons and Cognition · Quantitative Biology 2023-09-13 Sandra Nestler , Moritz Helias , Matthieu Gilson

Graph neural network (GNN) models are increasingly being used for the classification of electroencephalography (EEG) data. However, GNN-based diagnosis of neurological disorders, such as Alzheimer's disease (AD), remains a relatively…

Neurons and Cognition · Quantitative Biology 2023-12-21 Dominik Klepl , Fei He , Min Wu , Daniel J. Blackburn , Ptolemaios G. Sarrigiannis

Alzheimer's disease (AD), a degenerative brain condition, can benefit from early prediction to slow its progression. As the disease progresses, patients typically undergo brain atrophy. Current prediction methods for Alzheimers disease…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Xin Honga , Jie Lin , Minghui Wang