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The COVID-19 disease has forced countries to make a considerable collaborative effort between scientists and governments to provide indicators to suitable follow-up the pandemic's consequences. Mathematical modeling plays a crucial role in…

Populations and Evolution · Quantitative Biology 2020-12-29 Patricio Cumsille , Oscar Rojas-Díaz , Pablo Moisset de Espanés

Propensity score methods have been shown to be powerful in obtaining efficient estimators of average treatment effect (ATE) from observational data, especially under the existence of confounding factors. When estimating, deciding which type…

Methodology · Statistics 2021-09-14 Kangjie Zhou , Jinzhu Jia

Due to the rapid geographic spread of the Aedes mosquito and the increase in dengue incidence, dengue fever has been an increasing concern for public health authorities in tropical and subtropical countries worldwide. Significant challenges…

For statistical inference on regression models with a diverging number of covariates, the existing literature typically makes sparsity assumptions on the inverse of the Fisher information matrix. Such assumptions, however, are often…

Methodology · Statistics 2021-06-08 Lu Xia , Bin Nan , Yi Li

Very unhealthy air quality is consistently connected with numerous diseases. Appropriate extreme analysis and accurate predictions are in rising demand for exploring potential linked causes and for providing suggestions for the…

Applications · Statistics 2023-08-25 Kai Wang , Chengxiu Ling , Ying Chen , Zhengjun Zhang

The analysis of case-control point pattern data is an important problem in spatial epidemiology. The spatial variation of cases if often compared to that of a set of controls to assess spatial risk variation as well as the detection of risk…

Methodology · Statistics 2025-03-20 Francisco Palmí-Perales , Finn Lindgren , Virgilio Gómez-Rubio

Governments and public health authorities use seroprevalence studies to guide responses to the COVID-19 pandemic. Seroprevalence surveys estimate the proportion of individuals who have detectable SARS-CoV-2 antibodies. However, serologic…

Applications · Statistics 2022-11-11 Samuel P. Rosin , Bonnie E. Shook-Sa , Stephen R. Cole , Michael G. Hudgens

Latent class analysis (LCA) is a useful tool to investigate the heterogeneity of a disease population with time-to-event data. We propose a new method based on non-parametric maximum likelihood estimator (NPMLE), which facilitates…

Methodology · Statistics 2022-02-03 Teng Fei , John Hanfelt , Limin Peng

In cohort studies, non-random medication use can pose barriers to estimation of the natural history trend in a mean biomarker value (namely, the association between a predictor of interest and a biomarker outcome that would be observed in…

Methodology · Statistics 2021-01-25 Andrew J. Spieker , Joseph A. C. Delaney , Robyn L. McClelland

This paper develops a large-scale Bayesian spatio-temporal binomial regression model for the purpose of investigating regional trends in antibody prevalence to Borrelia burgdorferi, the causative agent of Lyme disease. The proposed model…

In population studies on the etiology of disease, one goal is the estimation of the fraction of cases attributable to each of several causes. For example, pneumonia is a clinical diagnosis of lung infection that may be caused by viral,…

Applications · Statistics 2014-11-24 Zhenke Wu , Maria Deloria-Knoll , Laura L. Hammitt , Scott L. Zeger

Here we propose and implement a generalized mathematical model to find the time evolution of population in infectious diseases and apply the model to study the recent COVID-19 pandemic. Our model at the core is a non-local generalization of…

Populations and Evolution · Quantitative Biology 2020-05-01 Saumyak Mukherjee , Sayantan Mondal , Biman Bagchi

Stochastic compartmental models are important tools for understanding the course of infectious diseases epidemics in populations and in prospective evaluation of intervention policies. However, calculating the likelihood for discretely…

Computation · Statistics 2018-07-26 Lam Si Tung Ho , Forrest W. Crawford , Marc A. Suchard

We consider the SEIRS epidemiology model with such features of the COVID-19 outbreak as: abundance of unidentified infected individuals, limited time of immunity and a possibility of vaccination. The control of the pandemic dynamics is…

Populations and Evolution · Quantitative Biology 2026-03-31 J. Ilnytskyi , T. Patsahan

Insect species subject to infection, predation, and anisotropic environmental conditions may exhibit preferential movement patterns. Given the innate stochasticity of exogenous factors driving these patterns over short timescales,…

Machine Learning · Computer Science 2025-10-10 Seth Minor , Bret D. Elderd , Benjamin Van Allen , David M. Bortz , Vanja Dukic

Antimicrobial resistance (AMR) is a growing global crisis projected to cause 10 million deaths per year by 2050. While the WHO Global Antimicrobial Resistance and Use Surveillance System (GLASS) provides standardized surveillance data…

Machine Learning · Computer Science 2026-02-27 Md Tanvir Hasan Turja

We present an approach to studying and predicting the spatio-temporal progression of infectious diseases. We treat the problem by adopting a partial differential equation (PDE) version of the Susceptible, Infected, Recovered, Deceased…

Biological Physics · Physics 2021-04-30 Zhenlin Wang , Mariana Carrasco Teja , Xiaoxuan Zhang , Gregory Teichert , Krishna Garikipati

In this article we use global and regional data from the SARS epidemic in conjunction with a model of susceptible, exposed, infective, diagnosed, and recovered classes of people (``SEIJR'') to extract average properties and rate constants…

Other Quantitative Biology · Quantitative Biology 2007-05-23 Gerardo Chowell , Paul W. Fenimore , Melissa A. Castillo-Garsow , Carlos Castillo-Chavez

A demonstrated failure mode for operational solar flare forecasting is the inability to forecast flares that occur near, or just beyond, the solar limb. To address this shortcoming, we develop a "4pi" full-heliosphere event forecasting…

Solar and Stellar Astrophysics · Physics 2026-01-09 K. D. Leka , Eric L. Wagner , Lisa Upton , Bibhuti Kumar Jha , Kiran Jain , Sara Petty

Diffusion processes are governed by external triggers and internal dynamics in complex systems. Timely and cost-effective control of infectious disease spread critically relies on uncovering the underlying diffusion mechanisms, which is…

Populations and Evolution · Quantitative Biology 2022-02-09 Minkyoung Kim , Dean Paini , Raja Jurdak