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Molecular similarity plays a central role in ligand-based drug discovery, such as virtual screening, analog searching, and goal-directed molecular generation. However, traditional similarity measures, ranging from fingerprint-based Tanimoto…

Machine Learning · Computer Science 2026-04-28 Shiyun Wa , Yifei Wang , Simone Sciabola , Ye Wang

In many practical cases, a sensitivity analysis or an optimization of a complex time consuming computer code requires to build a fast running approximation of it - also called surrogate model. We consider in this paper the problem of…

Statistics Theory · Mathematics 2013-01-14 Loic Le Gratiet

We present a novel reduced-order fluid simulation technique leveraging Dynamic Mode Decomposition (DMD) to achieve fast, memory-efficient, and user-controllable subspace simulation. We demonstrate that our approach combines the strengths of…

Transfer learning leverages pre-trained model features from a large dataset to save time and resources when training new models for various tasks, potentially enhancing performance. Due to the lack of large datasets in the medical imaging…

Image and Video Processing · Electrical Eng. & Systems 2023-11-10 Gabriel Efrain Humpire-Mamani , Colin Jacobs , Mathias Prokop , Bram van Ginneken , Nikolas Lessmann

Over the past few years, the rapid development of deep learning technologies for computer vision has significantly improved the performance of medical image segmentation (MedISeg). However, the diverse implementation strategies of various…

Computer Vision and Pattern Recognition · Computer Science 2023-05-09 Dong Zhang , Yi Lin , Hao Chen , Zhuotao Tian , Xin Yang , Jinhui Tang , Kwang Ting Cheng

Next generation robots will need to understand intricate and articulated objects as they cooperate in human environments. To do so, these robots will need to move beyond their current abilities--- working with relatively simple objects in a…

Computer Vision and Pattern Recognition · Computer Science 2018-03-30 Abhishek Venkataraman , Brent Griffin , Jason J. Corso

Medical image segmentation plays a pivotal role in clinical diagnostics and treatment planning, yet existing models often face challenges in generalization and in handling both 2D and 3D data uniformly. In this paper, we introduce Medical…

Computer Vision and Pattern Recognition · Computer Science 2024-12-06 Jiayuan Zhu , Abdullah Hamdi , Yunli Qi , Yueming Jin , Junde Wu

Function fitting/approximation plays a fundamental role in computer graphics and other engineering applications. While recent advances have explored neural networks to address this task, these methods often rely on architectures with many…

Graphics · Computer Science 2025-05-28 Biao Zhang , Peter Wonka

Printing has drawn a lot of attention as a means of low per-unit cost and high throughput patterning of graphene inks for scaled-up thin-form factor device manufacturing. However, traditional printing processes require a flat surface and…

Accurate kinetic analysis of [$^{18}$F]FDG distribution in dynamic positron emission tomography (PET) requires anatomically constrained modelling of image-derived input functions (IDIFs). Traditionally, IDIFs are obtained from the aorta,…

Image and Video Processing · Electrical Eng. & Systems 2025-04-25 Valentin Langer , Kartikay Tehlan , Thomas Wendler

Rapid, reliable, and accurate interpretation of medical time-series signals is crucial for high-stakes clinical decision-making. Deep learning methods offered unprecedented performance in medical signal processing but at a cost: they were…

Signal Processing · Electrical Eng. & Systems 2024-10-08 Sully F. Chen , Zhicheng Guo , Cheng Ding , Xiao Hu , Cynthia Rudin

Accurate and computationally efficient 3D medical image segmentation remains a critical challenge in clinical workflows. Transformer-based architectures often demonstrate superior global contextual modeling but at the expense of excessive…

Image and Video Processing · Electrical Eng. & Systems 2026-02-19 Kavyansh Tyagi , Vishwas Rathi , Puneet Goyal

While three-dimensional imaging is essential for clinical diagnosis, its high cost and long wait times have motivated the use of image-to-3D foundation models to infer volume from two-dimensional modalities. However, because these models…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Yan Luo , Advaith Ravishankar , Serena Liu , Yutong Yang , Mengyu Wang

Semantic segmentation and activity classification are key components to creating intelligent surgical systems able to understand and assist clinical workflow. In the Operating Room, semantic segmentation is at the core of creating robots…

Computer Vision and Pattern Recognition · Computer Science 2024-07-09 Idris Hamoud , Alexandros Karargyris , Aidean Sharghi , Omid Mohareri , Nicolas Padoy

Open-vocabulary panoptic reconstruction is essential for advanced robotics perception and simulation. However, existing methods based on 3D Gaussian Splatting (3DGS) often struggle to simultaneously achieve geometric accuracy, coherent…

Robotics · Computer Science 2026-04-14 Xuan Yu , Yuxuan Xie , Changjian Jiang , Shichao Zhai , Rong Xiong , Yu Zhang , Yue Wang

Minimally invasive surgery (MIS) requires high-fidelity, real-time visual feedback of dynamic and low-texture surgical scenes. To address these requirements, we introduce FeatureEndo-4DGS (FE-4DGS), the first real time pipeline leveraging…

Computer Vision and Pattern Recognition · Computer Science 2025-11-14 Kai Li , Junhao Wang , William Han , Ding Zhao

Medical image segmentation is vital for clinical diagnosis, yet current deep learning methods often demand extensive expert effort, i.e., either through annotating large training datasets or providing prompts at inference time for each new…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Xingjian Li , Qifeng Wu , Adithya S. Ubaradka , Yiran Ding , Colleen Que , Runmin Jiang , Jianhua Xing , Tianyang Wang , Min Xu

This study investigates the effects of geometric model reduction on blood flow simulations in the patient-specific descending aorta, followed by speed-accuracy trade-off analysis using 3D simulations. We demonstrate how wall shear stresses…

Fluid Dynamics · Physics 2025-12-12 Rishi Kumar , K. Muralidhar , Indranil Saha Dalal

In this paper, we introduce S3D: A Spatial Steerable Surgical Drilling Framework for Robotic Spinal Fixation Procedures. S3D is designed to enable realistic steerable drilling while accounting for the anatomical constraints associated with…

While existing methods for 3D face reconstruction from in-the-wild images excel at recovering the overall face shape, they commonly miss subtle, extreme, asymmetric, or rarely observed expressions. We improve upon these methods with SMIRK…

Computer Vision and Pattern Recognition · Computer Science 2025-03-14 George Retsinas , Panagiotis P. Filntisis , Radek Danecek , Victoria F. Abrevaya , Anastasios Roussos , Timo Bolkart , Petros Maragos
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